Results 101 to 110 of about 12,534 (220)

Radioimmunotherapy in Non-Hodgkin’s Lymphoma: Retrospective Adverse Event Profiling of Zevalin and Bexxar

Pharmaceuticals, 2019
The development of monoclonal antibodies has dramatically changed the outcome of patients with non-Hodgkin’s lymphoma (NHL), the most common hematological malignancy.
Christos Sachpekidis, David B. Jackson, Theodoros G. Soldatos   +2 more
doaj   +1 more source

Biological intratumoral therapy for the high-grade glioma part II: vector- and cell-based therapies and radioimmunotherapy

CNS Oncology, 2019
Management of high-grade gliomas (HGGs) remains a complex challenge with an overall poor prognosis despite aggressive multimodal treatment. New translational research has focused on maximizing tumor cell eradication through improved tumor cell targeting ...
Joshua Loya, Charlie Zhang, Emily Cox, Achal S Achrol, Santosh Kesari   +4 more
doaj   +1 more source

Experimental and clinical approaches to a radioimmunotherapy in o

Сибирский онкологический журнал, 2016
Molecular nuclear medicine plays an important role in the diagnosis and therapy of cancer. Radioimmunodetection and radioimmunotherapy (RIT) involve the use of antibodies conjugated with diagnostic or therapeutic radionuclides, respectively.
E. V. Abakushina, D. N. Abakushin, Ju. N. Anohin   +2 more
doaj  

Radioimmunotherapy combating biofilm-associated infection in vitro

Frontiers in Medicine
BackgroundAddressing prosthetic joint infections poses a significant challenge within orthopedic surgery, marked by elevated morbidity and mortality rates. The presence of biofilms and infections attributed to Staphylococcus aureus (S.
Zijian Ye, Berend van der Wildt, F. Ruben H. A. Nurmohamed, J. Fred F. Hooning van Duyvenbode, Jos van Strijp, H. Charles Vogely, Marnix G. E. H. Lam, Ekaterina Dadachova, Harrie Weinans, Harrie Weinans, Bart C. H. van der Wal, Alex J. Poot   +11 more
doaj   +1 more source

Copper-67 as a therapeutic nuclide for radioimmunotherapy [PDF]

, 2018
.: The application of the beta particle-emitting nuclide 67Cu in radioimmunotherapy is reviewed. The production of the nuclide is outlined, and different production modes are discussed with an emphasis on cyclotron production.
Novak-Hofer, Ilse, Schubiger, August
core  

Cancer immunotherapy: current progress and applications [PDF]

, 2006
Cancer immunotherapy is a form of treatment protocol for cancer patients that have been studied intensively over the last two decades. The undesirable side effects during the course of conventional treatment have lead to the development of immunotherapy ...
Leong, Pooi Pooi, Seow, Heng Fong
core  

Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using 149Tb-rituximab [PDF]

, 2018
This study demonstrates high-efficiency sterilisation of single cancer cells in a SCID mouse model of leukaemia using rituximab, a monoclonal antibody that targets CD20, labelled with terbium-149, an alpha-emitting radionuclide.
Beyer, G.-J, Buchegger, F., Hartley, O., Künzi, G., Miederer, M., Senekowitsch-Schmidtke, R., Soloviev, D., Vranješ-Đurić, S., Čomor, J.   +8 more
core  

Targeting Cancer Stem Cells with Radioimmunotherapy: The Case of the Ovarian Cancer Stemness-Associated Biomarker L1CAM

International Journal of Translational Medicine
Cancer stem cells (CSCs) are a dynamic population of tumor cells characterized by long-term self-renewal, high tumorigenicity, resistance to conventional therapies such as radio- and chemotherapy, and capacity to recapitulate the tumor heterogeneity ...
Tihomir Zh. Todorov, Roger Schibli, Martin Béhé, Jürgen Grünberg   +3 more
doaj   +1 more source

In vitro characterization of 177Lu-radiolabelled chimeric anti-CD20 monoclonal antibody and a preliminary dosimetry study [PDF]

, 2018
Purpose: 131I- and 90Y-labelled anti-CD20 antibodies have been shown to be effective in the treatment of low-grade, B-cell non-Hodgkin's lymphoma (NHL).
Chen, Jianhua, Fani, Melpomeni, Forrer, Flavio, Lohri, Andreas, Maecke, Helmut, Moldenhauer, Gerhard, Müller-Brand, Jan, Powell, Pia   +7 more
core  

Recent preclinical and clinical advances in radioimmunotherapy for non-Hodgkin’s lymphoma

Exploration of Targeted Anti-tumor Therapy
Radioimmunotherapy (RIT) is a therapy that combines a radioactive nucleotide with a monoclonal antibody (mAb). RIT enhances the therapeutic effect of mAb and reduces toxicity compared with conventional treatment.
Hiroki Goto, Yoshioki Shiraishi, Seiji Okada   +2 more
doaj   +1 more source