Results 91 to 100 of about 9,215 (199)

The Curative Outcome of Radioimmunotherapy in a Mouse Breast Cancer Model Relies on mTOR Signaling

, 2014
Radiotherapy is a successful treatment modality for localized cancer. Our group has been exploring radiotherapy in combination with immunotherapy (radioimmunotherapy) to enhance systemic antitumor responses.
Verbrugge, Inge, W. Johnstone, Ricky, Verheij, Marcel, Neefjes, Jacques, Hagekyriakou, Jim, Gasparini, Alessia, Yagita, Hideo, Galli, Mara, I. Abrams, Scott, Stewart, Trina, M. Haynes, Nicole, Borst, Jannie   +11 more
core   +1 more source

Radioimmunotherapy in non-Hodgkin lymphoma: opinions of U.S. medical oncologists and hematologists

, 2010
Radioimmunotherapy is approved by the Food and Drug Administration for CD20 antigen-positive follicular and transformed non-Hodgkin lymphoma. The goal of this study was to obtain the opinion of hematologists and medical oncologists about CD20-directed ...
Schaefer, N G, Buchanan, J., Huang, P., Buchanan, J, Ma, J, Schaefer, N.G., Ma, J., Wahl, R.L., Huang, P, Wahl, R L   +9 more
core   +1 more source

Combination of 131I-anti-endoglin monoclonal antibody and 5-fluorouracil may be a promising combined-modality radioimmunotherapy strategy for the treatment of hepatocellular carcinoma

Biotechnology & Biotechnological Equipment, 2018
The present study aimed to investigate the therapeutic efficacy of combined radioimmunoconjugate 131I endoglin (ENG) and 5-fluorouracil (5-FU) in mouse model with hepatocellular carcinoma (HCC).
Chongling Duan, Yanxiang Li, Weifei Yang, Chao Zhang   +3 more
doaj   +1 more source

Radioimmunotherapy in Non-Hodgkin's Lymphoma: Retrospective Adverse Event Profiling of Zevalin and Bexxar. [PDF]

, 2019
The development of monoclonal antibodies has dramatically changed the outcome of patients with non-Hodgkin's lymphoma (NHL), the most common hematological malignancy.
Theodoros G. Soldatos, Sachpekidis, Christos, David B. Jackson, Jackson, David B, Soldatos, Theodoros G, Christos Sachpekidis, Sachpekidis C, Jackson DB, Soldatos TG   +8 more
core   +2 more sources

Pathogen-Specific Actinium-225 and Lutetium-177 Labeled Antibodies for Treatment of Biofilm-Associated Implant Infections: Initial In Vivo Proof-of-Concept

Antibiotics
Background: the primary challenge with implant infections is the formation of biofilm, which harbors dormant bacteria that reduce the effectiveness of antibiotics and amplify antibiotic resistance, exacerbating the global antimicrobial resistance crisis.
F. Ruben H. A. Nurmohamed, Kevin J. H. Allen, Mackenzie E. Malo, Connor Frank, J. Fred F. Hooning van Duvenbode, Berend van der Wildt, Alex J. Poot, Marnix G. E. H. Lam, Jos A. G. van Strijp, Peter G. J. Nikkels, H. Charles Vogely, Harrie Weinans, Ekaterina Dadachova, Bart C. H. van der Wal   +13 more
doaj   +1 more source

Combination Radioimmunotherapy Strategies for Solid Tumors

, 2019
Combination radioimmunotherapy is an emerging approach for the treatment of solid tumors where radio immunotherapy alone has proven to be reasonably ineffective. Radioimmunotherapy (RIT) using monoclonal antibodies (mAbs) labeled with radionuclides is an
Yong-Jin Lee, Javeria Zaheer, Jin Su Kim, Hyeongi Kim, Sang Moo Lim   +4 more
core   +1 more source

Radioimmunotherapy: A novel treatment of non-Hodgkin lymphoma [PDF]

, 2010
90Y-ibritumomab tiuxetan (Zevalin) and 131I-tositumomab (Bexxar) are current choices for radioimmunotherapy (RIT) of patients with follicular rituximab-relapsed or refractory CD20+ follicular B-cell NHL.
Tomislav Petrovic, Petrović Tomislav, Mihailović Jasna, Jasna Mihailovic   +3 more
core   +1 more source

Experimental and clinical approaches to a radioimmunotherapy in o

Сибирский онкологический журнал, 2016
Molecular nuclear medicine plays an important role in the diagnosis and therapy of cancer. Radioimmunodetection and radioimmunotherapy (RIT) involve the use of antibodies conjugated with diagnostic or therapeutic radionuclides, respectively.
E. V. Abakushina, D. N. Abakushin, Ju. N. Anohin   +2 more
doaj  

Radioimmunotherapy combating biofilm-associated infection in vitro

Frontiers in Medicine
BackgroundAddressing prosthetic joint infections poses a significant challenge within orthopedic surgery, marked by elevated morbidity and mortality rates. The presence of biofilms and infections attributed to Staphylococcus aureus (S.
Zijian Ye, Berend van der Wildt, F. Ruben H. A. Nurmohamed, J. Fred F. Hooning van Duyvenbode, Jos van Strijp, H. Charles Vogely, Marnix G. E. H. Lam, Ekaterina Dadachova, Harrie Weinans, Harrie Weinans, Bart C. H. van der Wal, Alex J. Poot   +11 more
doaj   +1 more source

Radioimmunotherapy of Ovarian Cancer

The International Journal of Biological Markers, 1993
Radioimmunotherapy (RIT) is a new therapeutical approach where radiolabeled monoclonal antibodies (MAb) against tumor-associated antigens are administered to treat tumor lesions. Ovarian cancer is one of the most promising fields for RIT. This paper gives an overview of some biodistribution studies in animal models and in patients with radiolabeled ...
openaire   +2 more sources