Results 121 to 130 of about 5,403 (175)
Evaluation of RC48-ADC in Combination with PRaG Regimen: An Open-Label, Prospective, Multicentre Study Assessing Efficacy and Safety for Advanced Refractory HER2-Expressing Solid Tumors (PRaG3.0 Study Protocol). [PDF]
Xu M +9 more
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Dosimetry and preclinical evaluation of long-term radiotoxicity following treatment with <sup>212</sup>Pb alpha-radioimmunotherapy targeting CD20. [PDF]
Quelven I +6 more
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PD-1 inhibitor improves radiosensitivity by tumor vessel normalization. [PDF]
Hao S +12 more
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Comparative In Vitro and In Vivo Evaluation of Anti-CCR8 Full-Sized IgG and Its Fab Fragments in Murine Colorectal Cancer Models. [PDF]
Hu T +5 more
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Cancer Radioimmunotherapy [PDF]
Targeting of radionuclides with antibodies, or radioimmunotherapy, has been an active field of research spanning nearly 50 years, evolving with advancing technologies in molecular biology and chemistry, and with many important preclinical and clinical studies illustrating the benefits, but also the challenges, which all forms of targeted therapies face.
David M Goldenberg
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An overview of radioimmunotherapy
Cancer Immunology Immunotherapy, 1991In reviewing the current state of affairs in radioimmunotherapy the paper focuses on the main difficulties thus far encountered and the procedures designed to avoid or circumvent these problems. The long range beta-emitters 90Y and 188Re have replaced 131I as the isotopes currently receiving most attention for use in radioimmunotherapy, and a range of ...
A, Maraveyas, A A, Epenetos
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Radioimmunodetection and Radioimmunotherapy
Cancer Investigation, 1984The development of monoclonal antibodies that recognize tumor-associated antigens has led to significantly greater practical possibilities for producing highly specific radiolabeled antibodies for diagnosis and therapy of human tumors. A number of problems remain before this technique will be ready for routine clinical application however.
S M, Larson +2 more
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Experimental radioimmunotherapy
Medical Physics, 1993Radiolabeled monoclonal antibodies have been used for radioimmunotherapy studies with human tumor spheroids and murine and human tumor xenografts in experimental animals. This paper reviews the work that has been performed in these models with different types of cancer, and highlights those papers that have presented dosimetry estimates and attempts to
D J, Buchsbaum +2 more
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