Results 51 to 60 of about 12,381 (205)
Bench to Bedside: Stability Studies of GMP Produced Trastuzumab-TCMC in Support of a Clinical Trial
Pharmaceuticals, 2015 The first-in-human phase 1 clinical radioimmunotherapy (RIT) trial with 212Pb-1,4,7,10-tetraaza-1,4,7,10-tetra-(2-carbamoylmethyl)-cyclododecane-trastuzumab (212Pb-TCMC-trastuzumab) was completed in October 2014 as a joint effort at the University of ...
Diane E. Milenic +2 more
doaj +1 more source
Nanotechnology and cancer [PDF]
, 2008 The biological picture of cancer is rapidly advancing from models built from phenomenological descriptions to network models derived from systems biology, which can capture the evolving pathophysiology of the disease at the molecular level.
Davis, Mark E., Heath, James R.
core +2 more sources
Intratumoral bacteria engineered for tumor therapy
Interdisciplinary Medicine, EarlyView.This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang +7 more
wiley +1 more source
Diagnostics, 2019 18F-FDG Positron Emission Tomography (PET) is used to monitor tumor response to 131I-therapy, but is confounded by prompt emissions (284, 364, 637, and 723 keV) from 131I, particularly in animal PET imaging.
Young Sub Lee +2 more
doaj +1 more source
Early Diagnosis of Alzheimer's disease by NIRF Spectroscopy and Nuclear Medicine [PDF]
, 2011 There is an urgent need for the early detection of diseases such as Alzheimer’s (AD) and Cancers in order to enable their successful treatment. Cancer is the second major cause of death after Heart Disease, and AD is the third major cause of death
I. C. Baianu
core +1 more source
Generation and in vivo characterization of a chimeric αvβ5-targeting antibody 14C5 and its derivatives [PDF]
, 2013 Background: Previous studies showed that radiolabeled murine monoclonal antibody (mAb) 14C5 and its Fab and F(ab')2 fragments, targeting αvβ5 integrin, have promising properties for diagnostic and therapeutic applications in cancer.
De Vos, Filip +5 more
core +2 more sources
Molecular theranostics: principles, challenges and controversies
Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley +1 more source
Aggregate, 2022 Therapeutic vaccines, an exciting development in cancer immunotherapy, share the goal of priming of personalized antigen‐specific T‐cell response by precise antigen presentation of dendritic cells (DCs), but major obstacles include insufficient antigen ...
Huan Yu +7 more
doaj +1 more source
Radioimmunotherapy for Acute Leukemia [PDF]
Cancer Control, 2002 The use of monoclonal antibodies to deliver radioactive isotopes directly to tumor cells has become a promising strategy to enhance the antitumor effects of native monoclonal antibodies. In this article, we summarize the role of radioimmunotherapy in the treatment of leukemia.The authors reviewed the published clinical trials of radioimmunotherapy in ...
John M, Burke +2 more
openaire +2 more sources
Early Diagnosis of Alzheimer's disease by NIRF Spectroscopy and Nuclear Medicine-v.4.0 [PDF]
, 2011 There is an urgent need for the early detection of diseases such as Alzheimer’s (AD) and Cancers in order to enable their successful treatment. Cancer is the second major cause of death after Heart Disease, and AD is the third major cause of death
I Baianu
core +1 more source