Results 51 to 60 of about 13,452 (195)

Evaluation of novel highly specific antibodies to cancer testis antigen Centrin‐1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer

open access: yesCancer Medicine, 2019
Background Pancreatic ductal adenocarcinoma (PDAC) accounts for >90% of pancreatic malignancies, and has median survival of 
Rubin Jiao   +9 more
doaj   +1 more source

Multifunctional Au@AgBiS2 Nanoparticles as High‐Efficiency Radiosensitizers to Induce Pyroptosis for Cancer Radioimmunotherapy

open access: yesAdvanced Science, 2023
Radiotherapy (RT), a widely used clinical treatment modality for cancer, uses high‐energy irradiation for reactive oxygen species (ROS) production and DNA damage.
Liang Xiao   +6 more
doaj   +1 more source

Radioimmunotherapy of Pancreatic Ductal Adenocarcinoma: A Review of the Current Status of Literature

open access: yesCancers, 2020
Pancreatic ductal adenocarcinoma (PDAC) has long been associated with low survival rates. A lack of accurate diagnostic tests and limited treatment options contribute to the poor prognosis of PDAC.
Ashleigh Hull   +5 more
semanticscholar   +1 more source

RADIOIMMUNOTHERAPY IN THE TREATMENT OF MALIGNANCIES

open access: yesСибирский онкологический журнал, 2016
This review presents information about one of the promising areas of targeted therapy in modern oncology, which is called radioimmunotherapy. Particular attention is paid to the possibility of clinical application of this type of systemic treatment for ...
V. I. Chernov   +4 more
doaj   +1 more source

90Yttrium Ibritumomab Tiuxetan (Zevalin) for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Report of 5 Cases

open access: yesBlood and Lymphatic Cancer: Targets and Therapy, 2023
Jing Wang,1 Firas Baidoun,2 Han W Tun,2 Muhamad Alhaj Moustafa2 1Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL, 32224, USA; 2Division of Hematology and Medical Oncology, Mayo Clinic Florida, Jacksonville, FL, 32224 ...
Wang J   +3 more
doaj  

From netrin‐1‐targeted SPECT/CT to internal radiotherapy for management of advanced solid tumors

open access: yesEMBO Molecular Medicine, 2023
Targeted radionuclide therapy is a revolutionary tool for the treatment of highly spread metastatic cancers. Most current approaches rely on the use of vectors to deliver radionuclides to tumor cells, targeting membrane‐bound cancer‐specific moieties ...
David Kryza   +20 more
doaj   +1 more source

Leveraging Bioorthogonal Click Chemistry to Improve 225Ac-Radioimmunotherapy of Pancreatic Ductal Adenocarcinoma

open access: yesClinical Cancer Research, 2018
Purpose: Interest in targeted alpha-therapy has surged due to α-particles' high cytotoxicity. However, the widespread clinical use of this approach could be limited by on-/off-target toxicities.
S. Poty   +8 more
semanticscholar   +1 more source

Combination Radioimmunotherapy Strategies for Solid Tumors

open access: yesInternational Journal of Molecular Sciences, 2019
Combination radioimmunotherapy is an emerging approach for the treatment of solid tumors where radio immunotherapy alone has proven to be reasonably ineffective. Radioimmunotherapy (RIT) using monoclonal antibodies (mAbs) labeled with radionuclides is an
Javeria Zaheer   +4 more
semanticscholar   +1 more source

Comparative Radioimmunotherapy of Experimental Melanoma with Novel Humanized Antibody to Melanin Labeled with 213Bismuth and 177Lutetium

open access: yesPharmaceutics, 2019
Melanoma is a cancer with increasing incidence and there is a need for alternatives to immunotherapy within effective approaches to treatment of metastatic melanoma.
Kevin J. H. Allen   +6 more
doaj   +1 more source

212Pb α-Radioimmunotherapy Targeting CD38 in Multiple Myeloma: A Preclinical Study

open access: yesJournal of Nuclear Medicine, 2019
Multiple myeloma (MM) is a plasma cell cancer and represents the second most frequent hematologic malignancy. Despite new treatments and protocols, including high-dose chemotherapy associated with autologous stem cell transplantation, the prognosis of MM
I. Quelven   +8 more
semanticscholar   +1 more source

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