Results 31 to 40 of about 9,215 (199)
Radioimmunotherapy of Infectious Diseases [PDF]
Seminars in Nuclear Medicine, 2009 The need for novel approaches to treat infectious diseases is obvious and urgent. This situation has renewed interest in the use of monoclonal antibodies (mAbs) to treat infectious diseases. During the last 5 years, radioimmunotherapy (RIT), a modality developed for cancer treatment, has been successfully adapted for the treatment of experimental ...
Ekaterina, Dadachova, Arturo, Casadevall
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A Biomathematical Model of Tumor Response to Radioimmunotherapy with PDL1 and CTLA4 [PDF]
, 2022 There is evidence of synergy between radiotherapy and immunotherapy. Radiotherapy can increase liberation of tumor antigens, causing activation of antitumor T-cells. This effect can be boosted with immunotherapy.
Pardo-Montero, J +4 more
core +1 more source
Radioimmunotherapy of human tumours [PDF]
Nature Reviews Cancer, 2015 The eradication of cancer remains a vexing problem despite recent advances in our understanding of the molecular basis of neoplasia. One therapeutic approach that has demonstrated potential involves the selective targeting of radionuclides to cancer-associated cell surface antigens using monoclonal antibodies.
Steven M, Larson +3 more
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Frontiers in Oncology, 2018 Radiation-induced chromosomal aberrations represent an early marker of late effects, including cell killing and transformation. The measurement of cytogenetic damage in tissues, generally in blood lymphocytes, from patients treated with radiotherapy has ...
Marco Durante, Silvia C. Formenti
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Frontiers in Oncology, 2021 The prognosis of advanced malignant tumors is very poor, and effective treatment is limited. Radioimmunotherapy (RIT) is a novel treatment method. However, its anti-tumor effect is relatively low in solid tumors, which is mainly due to the blood-tumor ...
Binwei Lin +9 more
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Re-188 Enhances the Inhibitory Effect of Bevacizumab in Non-Small-Cell Lung Cancer
Molecules, 2016 The malignant behaviors of solid tumors such as growth, infiltration and metastasis are mainly nourished by tumor neovascularization. Thus, anti-angiogenic therapy is key to controlling tumor progression.
Jie Xiao +8 more
doaj +1 more source
Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy
Advanced Science, EarlyView.This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier +16 more
wiley +1 more source
Radioimmunotherapy (RIT) in Brain Tumors [PDF]
, 2019 Annually, the incidence of brain tumors has slightly increased and also the patient prognosis is still disappointing, especially for high-grade neoplasms. So, researchers seek methods to improve therapeutic index as a critical aim of treatment.
Gholamrezanezhad,, A +4 more
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Radioimmunotherapy of glioblastoma multiforme - Current status and future prospects
, 2021 Glioblastoma multiforme (GBM) or grade IV astrocytoma is the most diagnosed form of primary brain tumours in adults. Radioimmunotherapy (RIT), mostly in combination with conventional therapies, is presented in the current review as a therapeutic strategy
Hull, A., Marcu, L.G., Li, Y., Bezak, E.
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Radioimmunotherapy for Acute Leukemia [PDF]
Cancer Control, 2002 The use of monoclonal antibodies to deliver radioactive isotopes directly to tumor cells has become a promising strategy to enhance the antitumor effects of native monoclonal antibodies. In this article, we summarize the role of radioimmunotherapy in the treatment of leukemia.The authors reviewed the published clinical trials of radioimmunotherapy in ...
John M, Burke +2 more
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