Results 51 to 60 of about 5,403 (175)

Antibody conjugates in neuroblastoma: a step forward in precision medicine

open access: yesFrontiers in Oncology
Neuroblastoma (NB) is a pediatric cancer that often manifests in a high-risk form and is characterized by frequent relapses and resistance to conventional therapies.
Jihane Balla   +5 more
doaj   +1 more source

The Prognostic Value of Serum Inflammatory Markers in Nasopharyngeal Carcinoma Patients Treated With Immune Checkpoint Inhibitors: A Multicenter Study

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Although immune checkpoint inhibitors (ICIs) have revolutionized the treatment of nasopharyngeal carcinoma (NPC), reliable predictive biomarkers need to be further explored. This study aimed to investigate the predictive ability of inflammatory markers for poor prognosis in NPC patients treated with ICIs. Methods In this multicenter
Yang Xu   +12 more
wiley   +1 more source

Multifunctional Au@AgBiS2 Nanoparticles as High‐Efficiency Radiosensitizers to Induce Pyroptosis for Cancer Radioimmunotherapy

open access: yesAdvanced Science, 2023
Radiotherapy (RT), a widely used clinical treatment modality for cancer, uses high‐energy irradiation for reactive oxygen species (ROS) production and DNA damage.
Liang Xiao   +6 more
doaj   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

open access: yesiRADIOLOGY, Volume 4, Issue 3, Page 219-245, June 2026.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li   +4 more
wiley   +1 more source

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang   +6 more
wiley   +1 more source

Predictive Immunohistochemistry in Cholangiocarcinoma: Current Clinical Utility, Practical Limitations, and Emerging Directions

open access: yesAPMIS, Volume 134, Issue 6, June 2026.
ABSTRACT Cholangiocarcinoma (CCA) remains a difficult‐to‐treat biliary malignancy in which therapeutic stratification increasingly depends on predictive biomarkers. Although next‐generation sequencing is essential for the detection of targetable genomic alterations, immunohistochemistry (IHC) retains a practical role because it is widely available ...
Francesco Vasuri   +3 more
wiley   +1 more source

90Yttrium Ibritumomab Tiuxetan (Zevalin) for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Report of 5 Cases

open access: yesBlood and Lymphatic Cancer: Targets and Therapy, 2023
Jing Wang,1 Firas Baidoun,2 Han W Tun,2 Muhamad Alhaj Moustafa2 1Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL, 32224, USA; 2Division of Hematology and Medical Oncology, Mayo Clinic Florida, Jacksonville, FL, 32224 ...
Wang J   +3 more
doaj  

Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy

open access: yesCancer Science, Volume 117, Issue 6, Page 1543-1553, June 2026.
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen   +9 more
wiley   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

open access: yesChemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Radioimmunotherapy and colorectal cancer

open access: yesBritish Journal of Surgery, 2005
AbstractBackgroundDespite the success of radioimmunotherapy (RIT) using radiolabelled monoclonal antibodies (Mabs) directed against tumour-associated antigens in the treatment of non-Hodgkin's lymphoma, therapeutic success in solid tumours has been modest. In the past decade, a dozen Mabs have been investigated clinically for their potential usefulness
Koppe, M.J.   +3 more
openaire   +4 more sources

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