Results 21 to 30 of about 9,215 (199)
Seminars in Radiation Oncology, 2000 Radioimmunotherapy (RIT) is a promising new therapy for the treatment of a variety of malignancies. General principles of RIT are discussed, including important considerations in the selection of monoclonal antibodies (MAb) and radionuclides for RIT.
S J, Knox, R F, Meredith
openaire +2 more sources
Pretargeted radioimmunotherapy
International Journal of Radiation Oncology*Biology*Physics, 2006 This brief review covers the concept of pretargeted radioimmunotherapy and summarize the results obtained in preclinical animal models and initial phase I clinical trials. Reagents studied have been a bifunctional antibody prepared by crosslinking Fab' fragments from two antibodies with different specificity, one binding the target antigen expressed on
Ruby F, Meredith, Donald J, Buchsbaum
openaire +4 more sources
Fate of 177Lu-CHX-A”-DTPA-Rituximab: In vitro Evaluation in Raji Cell Line
Journal of Radiation and Cancer Research, 2023 Context: Radioimmunotherapy is an emerging treatment modality for various types of cancers. While immunotherapy using monoclonal antibodies has shown promising results, particularly in hematological malignancies, a significant number of patients develop ...
Saloni Arun Samant +2 more
doaj +1 more source
Experimental Hematology & Oncology, 2012 Background Repeated administration of antibody-based therapies such as radioimmunotherapy depends on preserved antigen expression in tumor lesions. The purpose of this study was to evaluate whether the antigen expression in metastases observed after ...
Elgström Erika +4 more
doaj +1 more source
Haematologica, 2008 Background The study aimed to evaluate FDG-PET imaging for early prediction of response to radioimmunotherapy in patients with non-Hodgkin’s lymphoma.Design and Methods Twenty-seven patients from a large ongoing, multicenter, phase I/II trial of ...
Caroline Bodet-Milin +10 more
doaj +1 more source
Current concepts of 131I therapy in oncology: Indications, methods and follow up [PDF]
Archive of Oncology, 2006 Radioiodine in various forms (as sodium iodide and as the iodinated compounds MIBG, LIPIODOL, et al.) has been used as a therapeutic agent in oncology. Differentiated thyroid carcinoma (DTC) has been successfully treated by 131I therapy.
Mihailović Jasna
doaj +1 more source
Pharmaceuticals, 2021 Background: Osteosarcoma (OS) has an overall patient survival rate of ~70% with no significant improvements in the last two decades, and novel effective treatments are needed.
Jaline Broqueza +8 more
doaj +1 more source
Current concepts of radioimmonotherapy for lymphoma [PDF]
Vojnosanitetski Pregled, 2015 nema
Mihailović Jasna +2 more
doaj +1 more source
Pretargeted Alpha Therapy of Disseminated Cancer Combining Click Chemistry and Astatine-211
Pharmaceuticals, 2023 To enhance targeting efficacy in the radioimmunotherapy of disseminated cancer, several pretargeting strategies have been developed. In pretargeted radioimmunotherapy, the tumor is pretargeted with a modified monoclonal antibody that has an affinity for ...
Chiara Timperanza +4 more
doaj +1 more source
World Journal of Nuclear Medicine, 2012 A Standard Operating Procedure (SOP) has been formulated for in-house preparation, quality control, dispensing and administration of 131 I-rituximab appropriate for the safe, effective, radioimmunotherapy of non-Hodgkin lymphoma.
Matthew Pickford, J. Turner
doaj +1 more source