Vaspin identified as a DNA‐binding serpin with functional consequences for protease inhibition
Vaspin is a serpin that is expressed in skin, adipose tissue, and liver. It binds to single‐ and double‐stranded DNA with high affinity. This binding is unaffected by mutation of the known heparin‐binding site, accelerates the inhibition of the inflammatory protease KLK7, and may contribute to vaspin's nuclear localization.
Kevin Möhlis +9 more
wiley +1 more source
Radiolabeling and evaluation of <sup>64+67</sup>Cu-2,2'-(1,2,4-Oxadiazole-3,5-diyl)di aniline as a theranostic agent for solid tumors. [PDF]
Gizawy MA +4 more
europepmc +1 more source
Respective Performance of 18 F-FDG PET and Radiolabeled Leukocyte Scintigraphy for the Diagnosis of Prosthetic Valve Endocarditis [PDF]
François Rouzet +9 more
openalex +1 more source
Sensing of cardiolipin exposure on plasma membranes of apoptotic cells by EryA‐mCherry protein
An aegerolysin protein erylysin A (EryA) fused with mCherry binds to artificial lipid vesicles supplemented with cardiolipin (CL). This binding is much more specific than that of annexin V, which binds various negatively charged glycerophospholipids (PG, PS, PI). In mammalian cells, the CL exposition at the membrane surface represents an early hallmark
Luka Žeželj +12 more
wiley +1 more source
Tailored Reaction Conditions and Automated Radiolabeling of [<sup>177</sup>Lu]Lu-PSMA-ALB-56 in a <sup>68</sup>Ga Setting: The Critical Impact of Antioxidant Concentrations. [PDF]
Vanney J +3 more
europepmc +1 more source
Abstract Objective This study aimed to explore the association between glymphatic function, as assessed by the diffusion tensor imaging along perivascular space (DTI‐ALPS) index, and headache frequency in individuals with migraine. Additionally, it evaluated whether sleep quality modulates this relationship.
Raffaele Ornello +9 more
wiley +1 more source
<sup>177</sup>Lu-Labeled Magnetic Nano-Formulations: Synthesis, Radio- and Physico-Chemical Characterization, Biological Applications, Current Challenges, and Future Perspectives. [PDF]
Halevas E, Varna D.
europepmc +1 more source
Abstract The tambaqui (Colossoma macropomum, G. Cuvier 1818) thrives both in the ion‐poor waters of the Amazon and in commercial aquaculture. In both, environmental conditions can be harsh due to low ion levels, occasional high salt challenges (in aquaculture), low pH, extreme PO2 levels (hypoxia and hyperoxia), high PCO2 levels (hypercapnia), high ...
Chris M. Wood +5 more
wiley +1 more source
Versatile Bifunctional PYTA Derivatives for <sup>225</sup>Ac Radiolabeling: A Comparison to Gold Standards. [PDF]
Cheveau M +8 more
europepmc +1 more source
Abstract The Amazonian loricariid fish Pterygoplichthys gibbiceps, from the Rio Negro, and Pterygoplichthys pardalis, from the Rio Solimões, are facultative air‐breathers that can use the stomach as an air‐breathing organ. Measurement of oxygen uptake under progressive aquatic hypoxia revealed a relatively high hypoxia resistance of both species.
Bernd Pelster +2 more
wiley +1 more source

