Results 171 to 180 of about 33,330 (276)

Expanding <sup>68</sup>Ga radiolabeling capacity: off-label use of PSMA-11 single vial cold kits through aliquoting and dual generator utilization. [PDF]

open access: yesEJNMMI Radiopharm Chem
Perrin O   +10 more
europepmc   +1 more source

Flavonoids as Modulators of Lipid Mediator Signaling: A Narrative Review on Mechanisms, Current Evidence, and Gaps in the Literature

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 20, 28 October 2026.
Flavonoid consumption may modulate phospholipase activity and COX‐, LOX‐, and CYP450‐dependent oxylipin biosynthesis, reshaping lipid mediator networks. Emerging evidence suggests these shifts may favor inflammatory resolution over propagation, with implications for metabolic, cardiovascular, and neuroinflammatory disease risk.
Joseph Arballo, Mary Ann Lila
wiley   +1 more source

Multiple‐TE Based Blood–Brain‐Barrier Water Exchange Time Measurement Using a TE‐Resolved 3D TSE Stack‐Of‐Spirals Readout

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1629-1644, October 2026.
ABSTRACT Purpose To develop a slice‐wise blurring‐free and densely sampled TE‐resolved multiple‐TE (mTE) ASL sequence (TASL) for measuring blood–brain barrier (BBB) water exchange time. Methods A 3D TSE spiral‐readout pCASL sequence was modified to enable TE‐resolved acquisition.
Bo Li   +11 more
wiley   +1 more source

Hyperpolarized MRI in Oncology—A Review of Clinical Studies and Evaluation of Preclinical Liver Studies

open access: yesNMR in Biomedicine, Volume 39, Issue 10, October 2026.
Hyperpolarized MRI is a promising clinical imaging modality in oncology, offering at least nine imaging contrasts obtainable with hyperpolarized [1‐13C]pyruvate as the injected agent, depending on the tissue and condition under investigation. Preclinical studies suggest that hyperpolarized MRI is warranted for detecting hepatocellular carcinoma within ...
Naama Lev‐Cohain   +2 more
wiley   +1 more source

Small Leucine‐Rich Proteoglycans in Cancer: Three Decades of Discovery

open access: yesProteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT Small leucine‐rich proteoglycans (SLRPs) are a well‐known family of extracellular matrix (ECM) molecules. They consist of five classes with 18 different protein cores originally recognized as having a physically supportive component to the extracellular structure and tissue integrity.
Gabriel J. Pascal   +5 more
wiley   +1 more source

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

open access: yesSmall, Volume 22, Issue 58, 16 October 2026.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros   +2 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

open access: yesVIEW, Volume 7, Issue 5, October 2026.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

open access: yesVIEW, Volume 7, Issue 5, October 2026.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf   +5 more
wiley   +1 more source

β‐Catenin‐Deficient Intervertebral Disc Cells Reduce Chemotactic Transcription and Myeloid Cell Recruitment to Injured Discs of Mice

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
(Left) In young discs, Wnt signaling‐replete nucleus pulposus cells secrete ECM components and, upon disc injury, cytokines to recruit myeloid cells. (Right) Whereas, β‐catenin‐deficient disc cells, modeling age‐related absence of Wnt signaling, exhibit reduced anabolic activity and, upon disc injury, secrete fewer pro‐inflammatory cytokines and ...
Tori M. Kroon   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy