Results 161 to 170 of about 33,330 (276)

Engineering intrinsically radiolabeled nanoparticles for imaging and therapy: a decade of design strategies and insights. [PDF]

RSC Adv
Ghosh S, Chakravarty R.
europepmc   +1 more source

Gastric Emptying in Obesity and Weight‐Loss Interventions: Physiology, Assessment, and Clinical Implications

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Obesity is associated with accelerated gastric emptying. Weight‐loss interventions each impose a distinct emptying signature: acceleration after sleeve gastrectomy and gastric bypass, delay after endoscopic sleeve gastroplasty, intragastric balloon, and GLP‐1 receptor agonists.
Maxime Amoyel, Rachida Lebtahi, Tigran Poghosyan, Maude Le Gall, Heithem Soliman   +4 more
wiley   +1 more source

Radiolabeled Angiopep-2 Peptide Vector as a Preclinical Platform for Blood-Brain Barrier Targeting: Synthesis, Radiolabeling, and Preliminary In Vivo Biodistribution in Mice. [PDF]

J Pept Sci
Fotou E, Apostolopoulou A, Bika CG, Giannakopoulou M, Bajwa DE, Moussis V, Tsikaris V, Gerothanassis IP, Alexiou GA, Bouziotis P, Tzakos AG.   +10 more
europepmc   +1 more source

Proteoliposome Preparation and Functional Reconstitution of Human Mitochondrial Transporters Via Wheat Germ Cell‐Free Expression System

Current Protocols, Volume 6, Issue 10, October 2026.
Abstract Mitochondrial membrane proteins play a crucial role in the transport of metabolites essential to cellular metabolism, and their dysfunction is linked to a wide range of metabolic diseases. Here, we present a method for the expression, reconstitution, and analysis of members of the solute carrier family 25 (SLC25), the largest family of human ...
Davood Kharaghani, Haotian Deng, Xiaoyang Su   +2 more
wiley   +1 more source

Fully GMP-complient radiosynthesis of [¹⁶¹Tb]Tb-PSMA-1 using the miniAiO synthesizer for clinical translation. [PDF]

EJNMMI Radiopharm Chem
Kryza D, Le Fur P, Badel JN, Morgat C, Khayi F, Giraudet AL.   +5 more
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, Volume 67, Issue 10, Page 5042-5074, October 2026.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Biocompatible Glycoconjugation Enables Sensitive In Vivo Cell Tracking by PET/CT. [PDF]

J Med Chem
Clemons N, Thickens AS, Lambert Lepesevich L, Rosenkrans ZT, Santoro-Fernandes V, Pinchuk AN, Aluicio-Sarduy E, Mixdorf JC, D'Souza SS, Caldon J, Kink J, Forsberg MH, Hematti P, Engle JW, Slukvin I, Capitini CM, Hernandez R.   +16 more
europepmc   +1 more source

Human biomarker navigator

iMeta, Volume 5, Issue 5, October 2026.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

The Second Nitrogen Fits: Development of Diazine-Based Macrocyclic Chelators to Stably Bind Radionuclides Used in Targeted Alpha Therapy. [PDF]

Inorg Chem
Blei MK, Waurick L, Drobot B, Brühlmann SA, Duchemin C, Mamis E, Inzamam M, Stora T, Audouin N, Sounalet T, Kopka K, Stumpf T, Stadlbauer S, Kretzschmar J, Mamat C.   +14 more
europepmc   +1 more source

Dual‐Targeted M1 Macrophage Extracellular Vesicles Reprogram the Tumor Microenvironment and Enhance Natural Killer Cell Immunotherapy in Breast Cancer

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Dual‐targeted extracellular vesicles (EV) engineered from M1 macrophages (M1EV_HA/cRGD) bridge NK cells to breast cancer cells while activating pro‐inflammatory programs within the tumor microenvironment. Hyaluronic acid (HA) enables CD44‐mediated NK targeting, and cRGD binds tumor integrins for targeted dual engagement.
Su Jin Kang, Gichan Baek, Suwun Ju, Gunhee Kim, Seongjin Gwak, Won Jong Rhee   +5 more
wiley   +1 more source