Results 161 to 170 of about 32,685 (264)

Design Strategies for Developing Chiral Macrocyclic Chelators as a Diagnostic Tool. [PDF]

Acc Chem Res
Zhu Y, Law GL.
europepmc   +1 more source

Disruption of starch biosynthesis and triacylglycerol degradation impairs growth but improves photosynthesis in Arabidopsis

New Phytologist, Volume 251, Issue 6, Page 3472-3488, September 2026.
Proposed model for altered carbon partitioning in wild‐type (a) and tgd1 sdp1 adg1‐1 Arabidopsis triple mutant (b). Summary Enhancing lipid accumulation by redirecting carbon from starch to triacylglycerol (TAG) in vegetative tissues is a promising strategy for developing high‐energy‐density crops for bioenergy production. However, our understanding of
Jilian Fan, Dongling Xie, Shivasharanappa S. Patil, Bagyalakshmi Muthan, Sanju A. Sanjaya, Changcheng Xu   +5 more
wiley   +1 more source

Exclusively Chemoselective <i>S</i>‑Acylation for Peptide Radiolabeling Using [¹⁸F]Fluoronicotinic Acid 4‑Nitrophenyl Ester as a Prosthetic Compound. [PDF]

ACS Omega
Nwaenie N, Karskela T, Dillemuth P, Rajander J, Laakkonen P, Airaksinen AJ, Li XG.   +6 more
europepmc   +1 more source

Chelator Free Radiolabeling and Preclinical Evaluation of η6‐Arene Sandwich Complexes of Lenalidomide With Rhenium and Technetium‐99m

ChemBioChem, Volume 27, Issue 16, 27 August 2026.
Direct, chelator‐free radiolabeling of lenalidomide is achieved via η6‐arene coordination to technetium‐99m and rhenium, forming sandwich complexes. The radiotracer shows rapid blood clearance, predominant renal excretion, and good in vivo stability, highlighting its potential as a pharmacokinetic probe.
Qaisar Nadeem, Federica Battistin, Daniel Hernández Valdés, Afaf R. Genady, Luis Rafael Silva Mendez, Saman Sadeghi, Olivier Blacque, Roger Alberto   +7 more
wiley   +1 more source

Fully Automated Azeotropic Drying-Free Synthesis of [¹⁸F]SynVesT-1 via Copper-Mediated Fluorination Using the Trasis All-in-One Module. [PDF]

Molecules
Basuli F, Shi J, Zhang X, Swenson RE.
europepmc   +1 more source

DNA–Peptide Crosslinks Placed at Codon 249 of the p53 Tumor Suppressor Gene Induce G to A Transitions in Human Cells

ChemBioChem, Volume 27, Issue 16, 27 August 2026.
DNA‐peptide cross‐links (DpCs) are ubiquitous DNA lesions that form when cellular proteins become covalently trapped on DNA strands and are processed by proteases. DpCs are hypothesized to play a role in antitumor activity of chemotherapeutic drugs and to contribute to aging.
Priscilla Yawson, Jan Henric T. Bacurio, Honnaiah Vijay Kumar, Natalia Y. Tretyakova, Ashis K. Basu   +4 more
wiley   +1 more source

Development of an automated radiosynthesis for [⁶⁸Ga]Ga-NODAGA[40Lys]-Exendin-4 in sodium acetate buffer. [PDF]

EJNMMI Radiopharm Chem
Ragot M, Reynaud-Orhon P, Revy A, Batisse-Lignier M, Brusseau V, Kelly A, Otman H, Cachin F, Chanchou M, Levesque S, Tempier M.   +10 more
europepmc   +1 more source

Sugar Amino Acid Linkers for the Design of [18F]SiFA‐PSMA Radioligands

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Sugar amino acid (SAA) linkers were incorporated into silicon‐fluoride‐acceptor (SiFA)‐prostate‐specific membrane antigen (PSMA) radioligands to modulate pharmacokinetic properties while preserving efficient 18F isotopic exchange radiolabeling. Furanose‐based SAAs outperformed pyranose analogues, enabling specific tumor visualization by PET despite ...
Narendar R. Gade, Melinda Wuest, Justin J. Bailey, Atul Bhardwaj, Ralf Schirrmacher, Frank Wuest   +5 more
wiley   +1 more source

In Vivo Imaging of a Photoactivatable Platinum Prodrug by Metal-Centered Radiolabeling. [PDF]

J Am Chem Soc
Firth G, Kim J, Shi H, Sunassee K, Zwaagstra O, Schilden KV, Blower PJ, Sadler PJ, Imberti C.   +8 more
europepmc   +1 more source

Evaluation of ⁸⁹Zr-DFO Functionalized Manganese-Iron Oxide Core-Shell Nanoparticles as a HER2-Targeted Multimodal Imaging Candidate Nanoplatform. [PDF]

ACS Omega
Özel D, Tunçel Oral A, Güleç S, Yurt F.   +3 more
europepmc   +1 more source