Results 71 to 80 of about 58,087 (312)

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab

Advanced Science, EarlyView.
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen, Keying Zhu, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Min Yang   +8 more
wiley   +1 more source

C2‐linked alkynyl poly‐ethylene glycol(PEG) adenosine conjugates as water‐soluble adenosine receptor agonists

Chemical Biology &Drug Design, Volume 101, Issue 2, Page 340-349, February 2023., 2023
Non‐cytotoxic C2‐linked alkynyl oligo ethylene glycol adenosine conjugates are highly water soluble and stimulate adenosine receptor activity. Abstract A series of 12 novel polyethylene‐glycol(PEG)‐alkynyl C2‐adenosine(ADN) conjugates were synthesized using a robust Sonogashira coupling protocol and characterized by NMR spectroscopy and mass ...
Lindsay Ferguson, Nasrin Shokrzadeh Madieh, Alexandra Vaideanu, Andreas Schatzlein, Joseph Festa, Harprit Singh, Geoffrey Wells, Sanjib Bhakta, Federico Brucoli   +8 more
wiley   +1 more source

Optimized simulations of 50Ti(p,α) and 49Ti(d,α) reactions for hospital-cyclotron production of 47Sc [PDF]

arXiv, 2023
The production of 47Sc, a promising radioisotope for targeted radionuclide therapy, by means of hospital-cyclotron reactions is investigated. Two possible routes are considered: the proton-induced reaction on enriched 50Ti targets and the deuteron-induced reaction on enriched 49Ti targets.
arxiv  

NEMA NU 2-2007 performance characteristics of GE Signa integrated PET/MR for different PET isotopes [PDF]

, 2019
BackgroundFully integrated PET/MR systems are being used frequently in clinical research and routine. National Electrical Manufacturers Association (NEMA) characterization of these systems is generally done with F-18 which is clinically the most relevant
D'Asseler, Yves, De Vasconcelos Caribé, Paulo Rauli Rafeson, Deller, Timothy W, Koole, M., Van Laere, K, Vandenberghe, Stefaan   +5 more
core   +1 more source

POSSIBILITIES OF SYSTEMIC RADIONUCLIDE THERAPY IN PALLIATIVE TREATMENT OF P ATIENTS WITH METASTATIC BONES DISEASE

Исследования и практика в медицине, 2015
The pain syndrome accompanying metastatic damage of bones, significantly reduces quality of patients life. In recent decades, medical practice implemented methods systemic radionuclide therapy of bone metastases using different radionuclides, which ...
A. D. Kaprin, A. A. Kostin, A. V. Leontyev, T. N. Lazutina, I. V. Pylova, L. V. Dushakova   +5 more
doaj   +1 more source

Near‐Infrared Organic Room Temperature Phosphorescent Probes Targeting Fibroblast Activation Protein for Surgical Navigation of Liver Cancer

Aggregate, EarlyView.
A near‐infrared organic room temperature phosphorescence probe of fibroblast‐activation protein in liver cancer microenvironment is prepared to accurately locate liver cancer and determine surgical margins, aiming at guiding hepatectomy and achieving accurate liver cancer resection.
Jinghua Li, Juqing Gu, Liangxuan Ding, Xiaomian Li, Peng Xia, Fusheng Liu, Xi Chen, Weijie Ma, Yong He, Qianqian Li, Zhen Li, Yufeng Yuan   +11 more
wiley   +1 more source

It is time to move forward into the era of Theranostics

EJNMMI Research, 2018
Radionuclide therapy, which until 15 years ago included only a few approved therapies, is gaining importance in the treatment of various malignancies. The future of oncology will not be limited to surgery, chemo-, antibody therapies or external radiation;
Hojjat Ahmadzadehfar, Markus Essler
doaj   +1 more source

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

Advanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu, Amar Salehi, Lei Xu, Wei Yuan, Tingting Yu   +4 more
wiley   +1 more source

Assessment of poststress left ventricular ejection fraction by gated SPECT: comparison with equilibrium radionuclide angiocardiography [PDF]

, 2010
PURPOSE: We compared left ventricular (LV) ejection fraction obtained by gated SPECT with that obtained by equilibrium radionuclide angiocardiography in a large cohort of patients.
ACAMPA, WANDA, Capasso E, Caprio MG, CUOCOLO, ALBERTO, De Luca S, Liuzzi R, Luongo L, Nicolai E, PETRETTA, MARIO   +8 more
core  

Introduction to Radiobiology of Targeted Radionuclide Therapy [PDF]

Frontiers in Medicine, 2015
During the last decades, new radionuclide-based targeted therapies have emerged as efficient tools for cancer treatment. Targeted radionuclide therapies (TRTs) are based on a multidisciplinary approach that involves the cooperation of specialists in several research fields.
Jean-Pierre ePOUGET, Catherine eLozza, Emmanuel eDeshayes, Emmanuel eDeshayes, Vincent eBoudousq, Isabelle eNAVARRO-TEULON, Isabelle eNAVARRO-TEULON   +6 more
openaire   +5 more sources