Results 141 to 150 of about 7,465 (248)

Improving image quality in terbium‐161 phantom imaging: Quantitative evaluation of DEW and TEW scatter correction methods

Journal of Applied Clinical Medical Physics, Volume 27, Issue 7, July 2026.
Abstract Background Terbium‐161 (Tb‐161) emits gamma rays and beta radiation, enabling both therapeutic and imaging applications. However, the multiple gamma emissions of 161Tb can affect image quality by increasing the scattering rate during SPECT imaging.
Melek Can, Gamze Çapa Kaya, Gül Gümüşer, Yasemin Parlak   +3 more
wiley   +1 more source

Radiolabeled Angiopep‐2 Peptide Vector as a Preclinical Platform for Blood–Brain Barrier Targeting: Synthesis, Radiolabeling, and Preliminary In Vivo Biodistribution in Mice

Journal of Peptide Science, Volume 32, Issue 7, July 2026.
The developed DOTA‐Angiopep‐2 conjugate was well tolerated in glioma cells and enabled high‐yield radiolabeling with 177Lu and 161Tb. The 161Tb conjugate showed brain delivery with predominantly renal clearance, supporting a stable radiotheranostic platform for BBB‐targeted glioma therapy and SPECT imaging.
Evgenia Fotou, Adamantia Apostolopoulou, Christina‐Georgia Bika, Maria Giannakopoulou, Danai‐Efraimia Bajwa, Vassilios Moussis, Vassilios Tsikaris, Ioannis P. Gerothanassis, George A. Alexiou, Penelope Bouziotis, Andreas G. Tzakos   +10 more
wiley   +1 more source

Forcing the Side‐on π‐Coordination of a C≡C Triple Bond to Technetium Using the As,CC,As Alkyne Pincer Ligand 1,2‐Bis(2‐(diisopropylarsaneyl)‐4‐(trifluoromethyl)phenyl)Ethyne

Angewandte Chemie International Edition, Volume 65, Issue 25, 15 June 2026.
Technetium alkyne complexes have eluded isolation for decades with the only indicators for their existence being the isolation of vinylidene carbenes or their follow‐up reaction products despite plentiful of reports for neighboring elements. Stable, crystalline Tc(III) and Tc(V) alkyne complexes (and their Re analogs) have now been prepared and fully ...
Maximilian Roca Jungfer, Moritz Johannes Ernst, Lukas Eberle, Marius Kesselring, Guilhem Claude, Joachim Ballmann   +5 more
wiley   +1 more source

<b>Indic-Origin Radiotheranostics: Integrating Indian Medicinal Botanicals into Next-Generation Radiopharmaceutical Science</b>

Vidhyayana
Despite radiotheranostics being at the forefront of Precision Oncology, most radiopharmaceuticals in use today are based on synthetic ligands and/or synthetic peptides, which are often costly and unavailable in many geographies (Hofman et al., 2020; Hope et al., 2019).
null Aswathy Rajesh, null Amy Sharon Janet, null Noyal Babu   +2 more
openaire   +1 more source

Examining bidirectional longitudinal relationships between physical activity and physical function in older breast cancer survivors: The Thinking and Living with Cancer study

Cancer, Volume 132, Issue 12, 15 June 2026.
Abstract Background Older breast cancer survivors are susceptible to cancer‐ and treatment‐related losses in physical function that can negatively affect daily living activities, mobility, and independence. Although physical activity can improve physical function, few studies have focused on older survivors or explored interrelationships between ...
Ashley L. Artese, Xingtao Zhou, Brent J. Small, Tim A. Ahles, Jaeil Ahn, Traci N. Bethea, Chloe C. Casagrande, Eunji Choi, Harvey J. Cohen, Martine Extermann, Deena Graham, Katherine Hall, Claudine Isaacs, Heather S. L. Jim, Cynthia D. J. Kusters, Brenna C. McDonald, Zev M. Nakamura, Sunita K. Patel, Kelly E. Rentscher, James C. Root, Andrew J. Saykin, Kathleen Van Dyk, Wanting Zhai, Judith E. Carroll, Jeanne Mandelblatt   +24 more
wiley   +1 more source

Synthesis, docking, and preliminary in vitro/in vivo evaluation of MPP-dithiocarbamate-capped silver nanoparticle as dual-imaging agent for 5HT1A

International Journal of Nanomedicine, 2018
Shubhra Chaturvedi,1 Sangeeta Lal,2 Prasenjit Sen,3 Anil K Mishra1 1Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, New Delhi, Delhi, 2Department of Physics, B.S.
Chaturvedi S, Lal S, Sen P, Mishra AK
doaj  

Molecular Docking Study of Pramipexole Derivatives as Radiopharmaceutical Candidates for Brain Imaging

Neurodegenerative diseases are a global priority disease. According to the World Health Organization (WHO), it is estimated that by 2050, there will be 152 million people with neurodegenerative diseases.
Badra Sanditya Rattyananda, Iim Halimah, Teguh Hafiz Ambar Wibawa, Endah Rosyidiah, Isa Mahendra, Eva Maria Widyasari, Christerra Ellen Kusumaningrum, Witri Nuraeni, Hendris Wongso, Asep Rizaludin, Muhamad Basit Febrian, Titin Sri Mulyati, Maula Eka Sriyani, Ahmad Kurniawan, Yanuar Setiadi   +14 more
core   +1 more source

SUBDUE‐3: SUB‐urothelial DUrvalumab‐89zirconium injEction; a phase 0 biodistribution study protocol

BJU International, EarlyView.
Kevin G. Keane, Richard Gauci, Roslyn J. Francis, Andrew M. Scott, Cynthia Hawks, Andrisha‐Jade Inderjeeth, Ian D. Davis, Jayne Lim, Andrew Redfern, Dickon Hayne   +9 more
wiley   +1 more source

WSB.APP/PS1 mice develop age‐dependent cerebral amyloid angiopathy, cerebrovascular dysfunction, and white matter deficits

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Cerebrovascular deficits, including cerebral amyloid angiopathy (CAA), play a key role in Alzheimer's disease (AD) pathogenesis. Here, we characterize the susceptibility of the WSB/EiJ genetic context to human AD‐relevant cerebrovascular phenotypes. METHODS CAA and parenchymal plaque analysis and in vivo neurovascular imaging were
Olivia J. Marola, Asli Uyar, Kelly J. Keezer, Juan Antonio K. Chong Chie, Kevin J. Elk, Abigail E. Cullen, Kierra Eldridge, Scott Persohn, Jonathan Nyandu Kanyinda, Jennifer D. Whitesell, Julie A. Harris, Paul Salama, Ashley E. Walker, Gregory W. Carter, Michael Sasner, Paul R. Territo, Gareth R. Howell, Kristen D. Onos   +17 more
wiley   +1 more source

Design and Construction of a Radiochemistry Laboratory and cGMP-Compliant Radiopharmacy Facility

The establishment of a compliant radiopharmacy facility within a university setting is crucial for supporting fundamental and preclinical studies, as well as for the production of high-quality radiopharmaceuticals for clinical testing in human protocols ...
Elaine Strauss, Jinda Fan, Abdullah Metebi, Kylie Smith, Angela Asor, Kurt Last   +5 more
core   +1 more source