Nuclear Medicine and Cancer Theragnostics: Basic Concepts [PDF]
Diagnostics, 2023 Cancer theragnostics is a novel approach that combines diagnostic imaging and radionuclide therapy. It is based on the use of a pair of radiopharmaceuticals, one optimized for positron emission tomography imaging through linkage to a proper radionuclide,
George A Alexiou +2 more
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Cancer theragnostics: closing the loop for advanced personalized cancer treatment through the platform integration of therapeutics and diagnostics [PDF]
Frontiers in Bioengineering and BiotechnologyCancer continues to be one of the leading causes of death worldwide, and conventional cancer therapies such as chemotherapy, radiation therapy, and surgery have limitations.
Anthony Guiseppi-Elie
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Emerging theragnostic radionuclide applications for hepatocellular carcinoma [PDF]
Frontiers in Nuclear Medicine, 2023 Hepatocellular carcinoma (HCC) is a major global health problem. Theragnostic is a term that refers to the integration of diagnostic and therapeutic modalities into a single system for personalized medicine.
N. E. Nyakale +7 more
doaj +4 more sources
Nanocarrier systems loaded with IR780, iron oxide nanoparticles and chlorambucil for cancer theragnostics [PDF]
Beilstein Journal of NanotechnologyTheragnostics has become a popular term nowadays, since it enables both diagnosis and therapy at the same time while only using one carrier platform.
Phuong-Thao Dang-Luong +5 more
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Enhancing Stability and Bioavailability of Peptidylglycine Alpha-Amidating Monooxygenase in Circulation for Clinical Use [PDF]
BiomoleculesPeptidylglycine alpha-amidating monooxygenase (PAM) is the only enzyme known to catalyze C-terminal amidation, a final post-translational modification step essential for the biological activity of over 70 bioactive peptides, including adrenomedullin (ADM)
Yulia Ilina +4 more
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Metabolic Priming as a Tool in Redox and Mitochondrial Theragnostics
Antioxidants, 2023 Theragnostics is a promising approach that integrates diagnostics and therapeutics into a single personalized strategy. To conduct effective theragnostic studies, it is essential to create an in vitro environment that accurately reflects the in vivo ...
Sónia Pinho +2 more
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Sandwich immunoassay for adrenomedullin precursor and its practical application [PDF]
Scientific ReportsAdrenomedullin (ADM) is a multifaceted peptide hormone involved in numerous physiological processes, including vascular stability, vasodilation, angiogenesis, and anti-inflammatory responses.
Paul Kaufmann +3 more
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PSMA theragnostics for metastatic castration resistant prostate cancer
Translational Oncology, 2022 There has been tremendous growth in the development of theragnostics for personalized cancer diagnosis and treatment over the past two decades. In prostate cancer, the new generation of prostate specific membrane antigen (PSMA) small molecular inhibitor ...
Hong Song, Kip E Guja, Andrei Iagaru
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Kinetics of adrenomedullin pathway activation in a porcine sepsis model and a human cohort of sepsis and septic shock [PDF]
Scientific ReportsSepsis is a life-threatening condition characterized by endothelial dysfunction. The peptide hormone adrenomedullin (ADM) plays a key role in sepsis owing to its potent vasodilatory effects, ability to maintain vascular integrity, and critical role in ...
Christoph Thiele +9 more
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Potential role of 68Ga- and 177Lu-cyclic pentapeptides for in-vivo targeting CXCR4 receptor expression in chemotherapy relapse MCL patient [PDF]
Asia Oceania Journal of Nuclear Medicine and BiologyObjective(s): High levels of CXCR4 expression in patients with mantle cell lymphoma is associated with poor prognosis. Various molecular techniques used are unable to specify the metastatic disease burden.
Tamanna Lakhanpal +6 more
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