Cancer theragnostics: closing the loop for advanced personalized cancer treatment through the platform integration of therapeutics and diagnostics [PDF]
Frontiers in Bioengineering and BiotechnologyCancer continues to be one of the leading causes of death worldwide, and conventional cancer therapies such as chemotherapy, radiation therapy, and surgery have limitations.
Liang Luo, Guiseppi-Elie Anthony
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Nuclear Medicine and Cancer Theragnostics: Basic Concepts [PDF]
Diagnostics, 2023 Cancer theragnostics is a novel approach that combines diagnostic imaging and radionuclide therapy. It is based on the use of a pair of radiopharmaceuticals, one optimized for positron emission tomography imaging through linkage to a proper radionuclide,
George A Alexiou +2 more
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Nanocarrier systems loaded with IR780, iron oxide nanoparticles and chlorambucil for cancer theragnostics [PDF]
Beilstein Journal of NanotechnologyTheragnostics has become a popular term nowadays, since it enables both diagnosis and therapy at the same time while only using one carrier platform.
Phuong-Thao Dang-Luong +5 more
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Emerging theragnostic radionuclide applications for hepatocellular carcinoma [PDF]
Frontiers in Nuclear Medicine, 2023 Hepatocellular carcinoma (HCC) is a major global health problem. Theragnostic is a term that refers to the integration of diagnostic and therapeutic modalities into a single system for personalized medicine.
N. E. Nyakale +7 more
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Metabolic Priming as a Tool in Redox and Mitochondrial Theragnostics
Antioxidants, 2023 Theragnostics is a promising approach that integrates diagnostics and therapeutics into a single personalized strategy. To conduct effective theragnostic studies, it is essential to create an in vitro environment that accurately reflects the in vivo ...
Sonia L C Pinho +2 more
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Biomaterials’ Role in Improving Patient Care from Drug Testing and Delivery to Theragnostics and Regenerative Medicine [PDF]
Journal of Functional BiomaterialsOver the past 200 years (1820–2020), global life expectancy has nearly tripled, increasing from 26 to 72.91 years, due to factors such as poverty reduction and public health initiatives. Today, society faces different challenges than it did centuries ago.
Sabina Cristiana Badulescu +4 more
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Enhancing Stability and Bioavailability of Peptidylglycine Alpha-Amidating Monooxygenase in Circulation for Clinical Use [PDF]
BiomoleculesPeptidylglycine alpha-amidating monooxygenase (PAM) is the only enzyme known to catalyze C-terminal amidation, a final post-translational modification step essential for the biological activity of over 70 bioactive peptides, including adrenomedullin (ADM)
Yulia Ilina +4 more
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Molecular Imaging and Theragnostics of Thyroid Cancers [PDF]
Cancers, 2022 Molecular imaging plays an important role in the evaluation and management of different thyroid cancer histotypes. The existing risk stratification models can be refined, by incorporation of tumor-specific molecular markers that have theranostic power, to optimize patient-specific (individualized) treatment decisions.
Luca Giovanella +2 more
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Targeted Drug Delivery and Theragnostics
Current Pharmaceutical Design, 2020 Kalevi Kairemo
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Life, 2023 Nuclear medicine has acquired a crucial role in the management of patients with neuroendocrine neoplasms (NENs) by improving the accuracy of diagnosis and staging as well as their risk stratification and personalized therapies, including radioligand ...
Riccardo Laudicella +2 more
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