Results 41 to 50 of about 1,533 (199)

Upper airway disease diagnosis as a predictive biomarker of therapeutic response to biologics in severe asthma

Frontiers in Medicine, 2023
Asthma is a heterogeneous disease sharing airway instability but with different biology, risk factors, and response-to-therapy patterns. Biologics have revolutionized the one-size-fits-to-all approach to personalized medicine in severe asthma (SA), which
Sophie Cottin, Virginie Doyen, Charles Pilette, Charles Pilette   +3 more
doaj   +1 more source

NeoBOMB1, a GRPR-Antagonist for Breast Cancer Theragnostics: First Results of a Preclinical Study with [67Ga]NeoBOMB1 in T-47D Cells and Tumor-Bearing Mice

Molecules, 2017
Background: The GRPR-antagonist-based radioligands [67/68Ga/111In/177Lu]NeoBOMB1 have shown excellent theragnostic profiles in preclinical prostate cancer models, while [68Ga]NeoBOMB1 effectively visualized prostate cancer lesions in patients.
Aikaterini Kaloudi, Emmanouil Lymperis, Athina Giarika, Simone Dalm, Francesca Orlandi, Donato Barbato, Mattia Tedesco, Theodosia Maina, Marion de Jong, Berthold A. Nock   +9 more
doaj   +1 more source

Gold-Nanoparticle Hybrid Nanostructures for Multimodal Cancer Therapy

Nanomaterials, 2022
With the urgent need for bio-nanomaterials to improve the currently available cancer treatments, gold nanoparticle (GNP) hybrid nanostructures are rapidly rising as promising multimodal candidates for cancer therapy.
Amaal Abdulraqeb Ali, Waad H. Abuwatfa, Mohammad H. Al-Sayah, Ghaleb A. Husseini   +3 more
doaj   +1 more source

Aptamers as Theragnostic Tools in Prostate Cancer

Biomolecules, 2022
Despite of the capacity that several drugs have for specific inhibition of the androgen receptor (AR), in most cases, PCa progresses to an androgen-independent stage. In this context, the development of new targeted therapies for prostate cancer (PCa) has remained as a challenge.
Carlos David Cruz-Hernández, Griselda Rodríguez-Martínez, Sergio A. Cortés-Ramírez, Miguel Morales-Pacheco, Marian Cruz-Burgos, Alberto Losada-García, Juan Pablo Reyes-Grajeda, Imelda González-Ramírez, Vanessa González-Covarrubias, Ignacio Camacho-Arroyo, Marco Cerbón, Mauricio Rodríguez-Dorantes   +11 more
openaire   +3 more sources

Theragnostics - new methods in nuclear medicine

, 2022
The main topic of the bachelor thesis is theragnostics - new methods in nuclear medicine. Theragnostics is a personalized treatment strategy that combines diagnostics with therapy and finds application primarily in the treatment of cancer.
PROCHÁZKOVÁ, Michaela
core  

Theragnostics of TRK-targeting agents (trackins): a challenge that promises reward

, 2022
Therminologically, theragnostics combines therapeutics and diagnostics. Life at cellular and molecular level is a binary event (e.g., phosphorylation-dephosphorylation of proteins, methylation-demethylations of DNA and acetylation-deacetylation of ...
Tonchev, Anton B.; Medical University of Varna, Ghenev, Peter I.; Medical University of Varna, Vinciguerra, Manlio; Medical University of Varna, Evtimov, Nikolai T.; Department of Urology, Saint Anna Hospital, Varna, Yanev, Stanislav; Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia, Aloe, Luigi; Fondazione Iret, Tecnopolo R. Levi-Montalcini, Rome, Panayotova, Daniela; Division of Cardiology, Department of Cardiac Surgery, Saint Marina University Hospital, Fiore, Marco; Institute of Biochemistry and Cell Biology, Section of Neurobiology Rita Levi-Montalcini, National Research Council (CNR), Rome, Chaldakov, George N.; Medical University of Varna   +8 more
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Shifting emphasis from pharmacogenomics to theragnostics [PDF]

Nature Biotechnology, 2006
What will be the role of theragnostic patents in upstream and downstream biomarker research?
Ozdemir, Vural, Williams-Jones, Bryn, Glatt, Stephen J, Tsuang, Ming T, Lohr, James B, Reist, Christopher   +5 more
openaire   +2 more sources

Theragnostics: See what you treat and treat what you see

, 2021
Theragnostics is not a new conception, even if nowadays it is gaining more and more importance in clinical practice and interest among researchers, thanks to their great results obtained in oncologic (especially in neuroendocrine tumors) and non ...
Iacomino A., Cuccurullo V., Marino A., Manni D.   +3 more
core  

Nanotechnology: A Promising Approach for Cancer Diagnosis, Therapeutics and Theragnosis

International Journal of Nanomedicine, 2022
Mesfin Dessale, Getachew Mengistu, Hylemariam Mihiretie Mengist Department of Medical Laboratory Sciences, Debre Markos University, Debre Markos, Amhara, EthiopiaCorrespondence: Hylemariam Mihiretie Mengist, Email hylemariam@gmail.comAbstract: Cancer ...
Dessale M, Mengistu G, Mengist HM
doaj  

131 SPECT/CT of Abdominal False-Positive Uptake: Radioiodine Gallbladder Accumulation Mimics Hepatic Metastasis from Thyroid Carcinoma

Endocrinology Research and Practice
The use of radioactive 131I (Iodine) to treat well-differentiated thyroid carcinomas is a well-established practice. However, in some cases, 131I may be retained in the gallbladder, leading to false-positive results in the detection of thyroid cancer ...
Mario Leporace, Ferdinando Calabria, Antonio Lanzillotta   +2 more
doaj   +1 more source