Results 31 to 40 of about 2,465 (209)

Unleashing novel horizons in advanced prostate cancer treatment: investigating the potential of prostate specific membrane antigen-targeted nanomedicine-based combination therapy

open access: yesFrontiers in Immunology, 2023
Prostate cancer (PCa) is a prevalent malignancy with increasing incidence in middle-aged and older men. Despite various treatment options, advanced metastatic PCa remains challenging with poor prognosis and limited effective therapies. Nanomedicine, with
Mingze He   +11 more
doaj   +1 more source

Post-acute Brain Injury Urinary Signature: A New Resource for Molecular Diagnostics [PDF]

open access: yes, 2014
Heterogeneity within brain injury presents a challenge to the development of informative molecular diagnostics. Recent studies show progress particularly in cerebrospinal fluid with biomarker assays targeting one or a few structural proteins.
Cifu, David X.   +5 more
core   +2 more sources

Commentary: Opportunities for research in molecular radiotherapy [PDF]

open access: yes, 2017
Cancer has been treated with radiopharmaceuticals for 80 years. A recent National Cancer Research Institute report from the Clinical and Translational Radiotherapy Research Working Group reviews the current status of molecular radiotherapy and has ...
Flux, Glenn D   +3 more
core   +2 more sources

PET Oncological Radiopharmaceuticals: Current Status and Perspectives

open access: yesMolecules, 2022
Molecular imaging is the visual representation of biological processes that take place at the cellular or molecular level in living organisms. To date, molecular imaging plays an important role in the transition from conventional medical practice to ...
Mai Lin   +4 more
doaj   +1 more source

Studies on the biodistribution of dextrin nanoparticles [PDF]

open access: yes, 2010
The characterization of biodistribution is a central requirement in the development of biomedical applications based on the use of nanoparticles, in particular for controlled drug delivery.
Ferreira, M. F. M.   +6 more
core   +1 more source

Artificial neural networks for 3D cell shape recognition from confocal images

open access: yes, 2020
We present a dual-stage neural network architecture for analyzing fine shape details from microscopy recordings in 3D. The system, tested on red blood cells, uses training data from both healthy donors and patients with a congenital blood disease ...
Bianchi, P.   +9 more
core   +2 more sources

Upper airway disease diagnosis as a predictive biomarker of therapeutic response to biologics in severe asthma

open access: yesFrontiers in Medicine, 2023
Asthma is a heterogeneous disease sharing airway instability but with different biology, risk factors, and response-to-therapy patterns. Biologics have revolutionized the one-size-fits-to-all approach to personalized medicine in severe asthma (SA), which
Sophie Cottin   +3 more
doaj   +1 more source

Targeted Fluoromagnetic Nanoparticles for Imaging of Breast Cancer MCF-7 Cells [PDF]

open access: yes, 2013
Purpose: To achieve simultaneous imaging and therapy potentials, targeted fluoromagnetic nanoparticles were synthesized and examined in human breast cancer MCF-7 cells.
Davoud Asgari   +7 more
core   +1 more source

Theragnostic Aspects and Radioimmunotherapy in Pediatric Tumors [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
The use of theragnostic radiopharmaceuticals in nuclear medicine has grown rapidly over the years to combine the diagnosis and therapy of tumors. In this review, we performed web-based and desktop literature research to investigate and explain the potential role of theragnostic imaging in pediatric oncology.
Andrea Cimini   +4 more
openaire   +3 more sources

NeoBOMB1, a GRPR-Antagonist for Breast Cancer Theragnostics: First Results of a Preclinical Study with [67Ga]NeoBOMB1 in T-47D Cells and Tumor-Bearing Mice

open access: yesMolecules, 2017
Background: The GRPR-antagonist-based radioligands [67/68Ga/111In/177Lu]NeoBOMB1 have shown excellent theragnostic profiles in preclinical prostate cancer models, while [68Ga]NeoBOMB1 effectively visualized prostate cancer lesions in patients.
Aikaterini Kaloudi   +9 more
doaj   +1 more source

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