Results 11 to 20 of about 2,465 (209)

Comparing the metabolomic landscape of polycystic ovary syndrome within urban and rural environments [PDF]

Communications Medicine
Background Polycystic Ovary Syndrome (PCOS) affects up to 10% of women of reproductive age, characterized by hormonal imbalances and metabolic complications. Environmental factors potentially influence the biochemical expression of this condition.
Jalpa Patel, Hiral Chaudhary, Abhishek Chudasama, Jaydeep Panchal, Akanksha Trivedi, Sonal Panchal, Trupti Joshi, Rushikesh Joshi   +7 more
doaj   +2 more sources

Prostate cancer theragnostics biomarkers: An update [PDF]

Investigative and Clinical Urology
Biomarkers are molecules such as proteins, genes, or other substances that may be tested to determine the stage of the tumor in a patient. The role of prostate cancer biomarkers is pivotal and the combination of prostate cancer immunotherapy with ...
Sathish Kumar AM, Prabhakar Rajan, Mohammad Alkhamees, Merrel Holley, Vinoth-Kumar Lakshmanan   +4 more
doaj   +3 more sources

Correction: Kinetics of adrenomedullin pathway activation in a porcine sepsis model and a human cohort of sepsis and septic shock [PDF]

Scientific Reports
Christoph Thiele, Yulia Ilina, Paul Kaufmann, Gero Springsfeld, Michaela Press, Oliver Hartmann, Andreas Bergmann, Thomas Breuer, Gernot Marx, Tim-Philip Simon   +9 more
doaj   +2 more sources

In vitro proof of concept studies of radiotoxicity from Auger electron-emitter thallium-201

EJNMMI Research, 2021
Background Auger electron-emitting radionuclides have potential in targeted treatment of small tumors. Thallium-201 (201Tl), a gamma-emitting radionuclide used in myocardial perfusion scintigraphy, decays by electron capture, releasing around 37 Auger ...
Katarzyna M. Osytek, Philip J. Blower, Ines M. Costa, Gareth E. Smith, Vincenzo Abbate, Samantha Y. A. Terry   +5 more
doaj   +3 more sources

Immunoassay-based quantification of full-length peptidylglycine alpha-amidating monooxygenase in human plasma

Scientific Reports, 2023
A one-step sandwich chemiluminescence immunometric assay (LIA) was developed for the quantification of bifunctional peptidylglycine-α-amidating monooxygenase (PAM) in human plasma (PAM-LIA).
Yulia Ilina, Paul Kaufmann, Olle Melander, Michaela Press, Katrin Thuene, Andreas Bergmann   +5 more
doaj   +1 more source

Novel insights into peptide amidation and amidating activity in the human circulation

Scientific Reports, 2021
C-terminal α-amidation is the final and essential step in the biosynthesis of several peptide hormones. Peptidylglycine α-amidating monooxygenase (PAM) is the only known enzyme to catalyse this reaction.
Paul Kaufmann, Andreas Bergmann, Olle Melander   +2 more
doaj   +1 more source

Positron Emission Tomography Molecular Imaging of the Major Neurodegenerative Disorders: Overview and Pictorial Essay, from a Nuclear Medicine Center's Perspective

Journal of Integrative Neuroscience, 2023
Computed tomography (CT) and magnetic resonance imaging (MRI) provide key structural information on brain pathophysiology. Positron emission tomography (PET) measures metabolism in the living brain; it plays an important role in molecular neuroimaging ...
Ferdinando Calabria, Mario Leporace, Andrea Cimini, Maria Ricci, Laura Travascio, Antonio Bagnato   +5 more
doaj   +1 more source

An integrated stewardship model: antimicrobial, infection prevention and diagnostic (AID) [PDF]

, 2015
Considering the threat of antimicrobial resistance and the difficulties it entails in treating infections, it is necessary to cross borders and approach infection management in an integrated, multidisciplinary manner.
Assen, Sander van, Dik, Jan-Willem H., Friedrich, Alexander W., Gemert-Pijnen, Julia E.W.C. van, Hendrix, Ron, Lo-Ten-Foe, Jerome R., Niesters, Hubert G.M., Panday, Prashant N., Poelman, Randy, Sinha, Bhanu   +9 more
core   +14 more sources

Peptide Receptor Radionuclide Therapy and Primary Brain Tumors: An Overview

Pharmaceuticals, 2021
Primary brain tumors (PBTs) are some of the most difficult types of cancer to treat, and despite advancements in surgery, chemotherapy and radiotherapy, new strategies for the treatment of PBTs are needed, especially for those with poor prognosis such as
Andrea Cimini, Maria Ricci, Francesca Russo, Martina Egidi, Ferdinando Calabria, Antonio Bagnato, Orazio Schillaci, Agostino Chiaravalloti   +7 more
doaj   +1 more source

Bacteriophages as Solid Tumor Theragnostic Agents [PDF]

International Journal of Molecular Sciences, 2021
Cancer, especially the solid tumor sub-set, poses considerable challenges to modern medicine owing to the unique physiological characteristics and substantial variations in each tumor’s microenvironmental niche fingerprints. Though there are many treatment methods available to treat solid tumors, still a considerable loss of life happens, due to the ...
Srivani Veeranarayanan, Aa Haeruman Azam, Kotaro Kiga, Shinya Watanabe, Longzhu Cui   +4 more
openaire   +2 more sources