Results 21 to 30 of about 1,533 (199)

Radiotherapy and inhibition of the EGF family as treatment strategies for prostate cancer: combining theragnostics with theragates [PDF]

Oncology Reviews, 2011
Prostate cancer is one of the most common solid tumors affecting men. Localized stages can be cured, however, once disseminated to distant organs the median survival drops below 12 months. The challenge for the future consists of unifying gained insights
Wolfgang Lilleby, Flavio Solca, Kathrine Røe   +2 more
doaj   +2 more sources

Advances in PSMA Alpha Theragnostics [PDF]

Seminars in Nuclear Medicine
Alpha theranostics offer an attractive alternative form of therapy, which has best been investigated and documented with 225Ac-PSMA in patients with prostate cancer. Advantages offered by targeted alpha therapy include overcoming radiation resistance, oxygen independence, effecting double-stranded DNA breakages within the tumors with anticipated ...
Mariza Vorster, Mike Sathekge
openaire   +4 more sources

An international multi-center investigation on the accuracy of radionuclide calibrators in nuclear medicine theragnostics [PDF]

, 2020
Background: Personalized molecular radiotherapy based on theragnostics requires accurate quantification of the amount of radiopharmaceutical activity administered to patients both in diagnostic and therapeutic applications.
Pooters, I.N.A. (Ivo N. A.), Wierts, R. (Roel), Jentzen, W. (Walter), Gotthardt, M. (Martin), Covens, P. (Peter), Vogg, A. (Andreas), Bauwens, M. (Matthias), Saldarriaga Vargas, C. (Clarita), Velden, F.H.P. (Floris) van, Mottaghy, F.M. (Felix M.), Pommé, S. (Stefaan), Segbers, M. (Marcel), Peters, S.M.B. (Steffie M. B.), Meyer Viol, S.L. (Sebastiaan L.), Wildberger, J.E. (Joachim)   +14 more
core   +5 more sources

Immunoassay-based quantification of full-length peptidylglycine alpha-amidating monooxygenase in human plasma

Scientific Reports, 2023
A one-step sandwich chemiluminescence immunometric assay (LIA) was developed for the quantification of bifunctional peptidylglycine-α-amidating monooxygenase (PAM) in human plasma (PAM-LIA).
Yulia Ilina, Paul Kaufmann, Olle Melander, Michaela Press, Katrin Thuene, Andreas Bergmann   +5 more
doaj   +1 more source

Current Challenges and Developments in Perovskite-Based Electrochemical Biosensors for Effective Theragnostics of Neurological Disorders [PDF]

, 2022
Early-stage diagnosis of neurological disease and effective therapeutics play a significant role in improving the chances of saving lives through suitable and personalized courses of treatment.
Badhulika, Sushmee, Durai, Lignesh
core   +1 more source

Positron Emission Tomography Molecular Imaging of the Major Neurodegenerative Disorders: Overview and Pictorial Essay, from a Nuclear Medicine Center's Perspective

Journal of Integrative Neuroscience, 2023
Computed tomography (CT) and magnetic resonance imaging (MRI) provide key structural information on brain pathophysiology. Positron emission tomography (PET) measures metabolism in the living brain; it plays an important role in molecular neuroimaging ...
Ferdinando Calabria, Mario Leporace, Andrea Cimini, Maria Ricci, Laura Travascio, Antonio Bagnato   +5 more
doaj   +1 more source

Novel insights into peptide amidation and amidating activity in the human circulation

Scientific Reports, 2021
C-terminal α-amidation is the final and essential step in the biosynthesis of several peptide hormones. Peptidylglycine α-amidating monooxygenase (PAM) is the only known enzyme to catalyse this reaction.
Paul Kaufmann, Andreas Bergmann, Olle Melander   +2 more
doaj   +1 more source

Magnetic nanoparticles for theragnostics [PDF]

Advanced Drug Delivery Reviews, 2009
Engineered magnetic nanoparticles (MNPs) represent a cutting-edge tool in medicine because they can be simultaneously functionalized and guided by a magnetic field. Use of MNPs has advanced magnetic resonance imaging (MRI), guided drug and gene delivery, magnetic hyperthermia cancer therapy, tissue engineering, cell tracking and bioseparation ...
Veronica I, Shubayev, Thomas R, Pisanic, Sungho, Jin   +2 more
openaire   +2 more sources

Theragnostics - Alternative production of terbium isotopes at the University of Birmingham using an MC40 cyclotron [PDF]

, 2019
In this work alternative methods for the production of terbium isotopes, and in particular 152Tb and 155Tb, have been investigated. These isotopes, which could be used for theragnostics, have been produced using an alpha and a proton beam incident on ...
Santa Rita, P, Russel, B, Pells, S, Parker, D. J, Robinson, A, Trinder, R. R, Wheldon, C, Ivanov, P, Pirrie, S, Allen, R, REGAN, PATRICK HENRY, WEBSTER, BENJAMIN LUKE, Kokalova, Tz, Phoenix, B, Cullen, D, Turner, A   +15 more
core   +2 more sources

Peptide Receptor Radionuclide Therapy and Primary Brain Tumors: An Overview

Pharmaceuticals, 2021
Primary brain tumors (PBTs) are some of the most difficult types of cancer to treat, and despite advancements in surgery, chemotherapy and radiotherapy, new strategies for the treatment of PBTs are needed, especially for those with poor prognosis such as
Andrea Cimini, Maria Ricci, Francesca Russo, Martina Egidi, Ferdinando Calabria, Antonio Bagnato, Orazio Schillaci, Agostino Chiaravalloti   +7 more
doaj   +1 more source