Results 21 to 30 of about 2,465 (209)

Mesoporous Silica Nanoparticles: Properties and Strategies for Enhancing Clinical Effect

Pharmaceutics, 2021
Due to the theragnostic potential of mesoporous silica nanoparticles (MSNs), these were extensively investigated as a novel approach to improve clinical outcomes.
Alex N. Frickenstein, Jordan M. Hagood, Collin N. Britten, Brandon S. Abbott, Molly W. McNally, Catherine A. Vopat, Eian G. Patterson, William M. MacCuaig, Ajay Jain, Keisha B. Walters, Lacey R. McNally   +10 more
doaj   +1 more source

Applications of Artificial Intelligence and Radiomics in Molecular Hybrid Imaging and Theragnostics for Neuro-Endocrine Neoplasms (NENs)

Life, 2023
Nuclear medicine has acquired a crucial role in the management of patients with neuroendocrine neoplasms (NENs) by improving the accuracy of diagnosis and staging as well as their risk stratification and personalized therapies, including radioligand ...
Michele Balma, Riccardo Laudicella, Elena Gallio, Sara Gusella, Leda Lorenzon, Simona Peano, Renato P. Costa, Osvaldo Rampado, Mohsen Farsad, Laura Evangelista, Desiree Deandreis, Alberto Papaleo, Virginia Liberini   +12 more
doaj   +1 more source

Preparation and Evaluation of ⁶⁴Cu-Radiolabled Dual-Ligand Multifunctional Gold Nanoparticles for Tumor Theragnosis

Pharmaceuticals, 2023
Gold nanoparticles (AuNPs) are cutting-edge platforms for combined diagnostic and therapeutic approaches due to their exquisite physicochemical and optical properties. Using the AuNPs physically produced by femtosecond pulsed laser ablation of bulk Au in
Karim Mhanna, Wei Qian, Ziyun Zhong, Allen F. Brooks, Erika Ouchi, Jenelle Stauff, Janna Arteaga, Maria Papachristou, Ioannis E. Datseris, Bing Liu, Xia Shao, Peter J. H. Scott   +11 more
doaj   +1 more source

Proteomics: in pursuit of effective traumatic brain injury therapeutics [PDF]

, 2015
Effective traumatic brain injury (TBI) therapeutics remain stubbornly elusive. Efforts in the field have been challenged by the heterogeneity of clinical TBI, with greater complexity among underlying molecular phenotypes than initially conceived.
Ahmed F, Andrew K Ottens, Bales JW, Begum G, Berger RP, Bonislawski DP, Bos R, Boulenguez P, Boutte AM, Brandner S, Brandner S, Campos-Martorell M, Cortes DF, Crawford F, Dachir S, Daoud H, Evans TM, Gackiere F, Gonzalez MI, Guingab-Cagmat JD, Gyorgy A, Gyorgy AB, Jaramillo ML, Jeter CB, Kabadi SV, Kabadi SV, Kahle KT, Kumar A, Levi S, Li BC, Liang J, Liang J, Lin WM, Loane DJ, Loov C, Lopez NE, Maier O, Manley GT, Maurer MH, Mehan ND, Mohseni S, Mondello S, Mondello S, Ottens AK, Ottens AK, Pavel N Lizhnyak, Prieto DA, Rau TF, Rosenfeld JV, Saatman KE, Schmid KE, Shen S, Shen Y, Siman R, Siman R, Sun C, Talley Watts L, Tsai YT, Wagner AK, Wu P, Xiong Y, Yu W, Zetterberg H, Zgavc T, Zhou XM   +64 more
core   +2 more sources

Bionanomedicine: A “Panacea” In Medicine? [PDF]

, 2017
Recent advances in nanotechnology, biotechnology, bioinformatics, and materials science have prompted novel developments in the field of nanomedicine. Enhancements in the theranostics, computational information, and management of diseases/disorders are ...
Anurogo, D. (Dito), Ikrar, T. (Taruna), Parikesit, A. A. (Arli)   +2 more
core   +1 more source

Molecular theranostics: principles, challenges and controversies. [PDF]

J Med Radiat Sci
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Currie G.
europepmc   +2 more sources

Micro/Nanobubbles Driven Multimodal Imaging and Theragnostics of Cancer [PDF]

Advanced Ultrasound in Diagnosis and Therapy, 2021
Ultrasound imaging has attracted great interest of researchers due to their application in cancer diagnosis and treatment. Ultrasound contrast agents, microbubbles and nanobubbles are widely explored as a multifunctional platform, not only carrying other
Xiaoting Zhang, BS, Zhifei Dai, PhD
doaj   +1 more source

Targeted Radiotherapeutics from 'Bench-to-Bedside'

CHIMIA, 2020
he concept of targeted radionuclide therapy (TRT) is the accurate and efficient delivery of radiation to disseminated cancer lesions while minimizing damage to healthy tissue and organs.
Cristina Müller, Martin Béhé, Susanne Geistlich, Nicholas P. van der Meulen, Roger Schibli   +4 more
doaj   +1 more source

Radiation Dosimetry of Theragnostic Pairs for Isotopes of Iodine in IAZA

Pharmaceutics, 2022
Theragnostic pairs of isotopes are used to infer radiation dosimetry for a therapeutic radiopharmaceutical from a diagnostic imaging study with the same tracer molecule labelled with an isotope better suited for the imaging task. We describe the transfer
Hans-S. Jans, Daria Stypinski, Piyush Kumar, John R. Mercer, Stephen A. McQuarrie, Alexander J. B. McEwan, Leonard I. Wiebe   +6 more
doaj   +1 more source

Ataxia-Telangiectasia Mutated and the Mre11-Rad50-NBS1 Complex:Promising Targets for Radiosensitization [PDF]

, 2012
Radiotherapy plays a central part in cancer treatment, and use of radiosensitizing agents can greatly enhance this modality. Although studies have shown that several chemotherapeutic agents have the potential to increase the radiosensitivity of tumor ...
Fujiwara, Toshiyoshi, Kuroda, Shinji, Urata, Yasuo   +2 more
core   +1 more source