Results 1 to 10 of about 54,631 (270)
The Radiobiology of Radiopharmaceuticals.
Seminars in Radiation Oncology, 2021 Radiopharmaceutical therapy or targeted radionuclide therapy (TRT) is a well-established class of cancer therapeutics that includes a growing number of FDA-approved drugs and a promising pipeline of experimental therapeutics. Radiobiology is fundamental to a mechanistic understanding of the therapeutic capacity of these agents and their potential ...
Z. Morris, Andrew Z. Wang, S. Knox
semanticscholar +4 more sources
Analysis of Radiopharmaceuticals [PDF]
Journal of AOAC INTERNATIONAL, 1971 Abstract Some of the activities of chemists engaged in evaluating and selecting analytical methodology for examination of radiopharmaceuticals and the criteria for assessment of their quality are described. Significant problems, as they relate to a regulatory analysis program, and tentative solutions to these problems are discussed ...
Max Jaffee, Leonard A. Ford
openalex +3 more sources
Radiopharmaceutical small-scale preparation in Europe: will we be able to harmonize the situation? [PDF]
EJNMMI Radiopharmacy and ChemistryBackground Radiopharmaceuticals have been considered a special group of medicines in Europe since 1989. The use of radiopharmaceuticals that have marketing authorization should always be the first option in clinical use, however due to their special ...
Estrella Moya +3 more
doaj +2 more sources
PSMA-Targeted Radiopharmaceuticals in Prostate Cancer: Current Data and New Trials
The Oncologist, 2023 Radiopharmaceuticals have been utilized for men with advanced prostate cancer for decades. Older agents, seldom used today, provided palliation for bone metastatic pain.
B. Ramnaraign, O. Sartor
semanticscholar +1 more source
Radiopharmaceuticals for PET and SPECT Imaging: A Literature Review over the Last Decade
International Journal of Molecular Sciences, 2022 Positron emission tomography (PET) uses radioactive tracers and enables the functional imaging of several metabolic processes, blood flow measurements, regional chemical composition, and/or chemical absorption.
George Crișan +5 more
semanticscholar +1 more source
Diagnostics, 2023 Radionuclides are unstable isotopes that mainly emit alpha (α), beta (β) or gamma (γ) radiation through radiation decay. Therefore, they are used in the biomedical field to label biomolecules or drugs for diagnostic imaging applications, such as positron
V. Benfante +14 more
semanticscholar +1 more source
Scientific Reports, 2022 Highest global cancer incidence of female breast cancer is a matter of great concern. HER2-positive breast cancers have high mortality rate hence detection at an early stage is vital for successful treatment, improved cancer care and survival rate ...
Amit Kumar Sharma +6 more
doaj +1 more source
Molecules, 2022 Therapeutic radiopharmaceuticals have been researched extensively in the last decade as a result of the growing research interest in personalized medicine to improve diagnostic accuracy and intensify intensive therapy while limiting side effects ...
H. A. Holik +5 more
semanticscholar +1 more source
Therapy with Radiopharmaceuticals [PDF]
Acta Oncologica, 2002 In an investigation by the Swedish Cancer Society, an expert group described the present status, critical issues and future aspects and potentials for each of nine major areas of radiation therapy research. The present report deals with therapy with radiopharmaceuticals.
Jörgen, Carlsson +4 more
openaire +3 more sources
Preparation and Preliminary Imaging of Novel Albumin-Binding PSMA Ligand ［177Lu］Lu-DOTA-CPN-PSMA
He huaxue yu fangshe huaxue, 2023 A novel PSMA targeting molecule ［177Lu］Lu-DOTA-CPN-PSMA with high uptake and long retention in prostate cancer was developed, in which DOTA was used as the bifunctional chelator, glutamic acid-urea-lysine(Glu-Urea-Lys) was used as the targeting group ...
LUO Tian-wei +7 more
doaj +1 more source