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The Radiobiology of Radiopharmaceuticals.
Seminars in Radiation Oncology, 2021 Radiopharmaceutical therapy or targeted radionuclide therapy (TRT) is a well-established class of cancer therapeutics that includes a growing number of FDA-approved drugs and a promising pipeline of experimental therapeutics. Radiobiology is fundamental to a mechanistic understanding of the therapeutic capacity of these agents and their potential ...
Z. Morris, Andrew Z. Wang, S. Knox
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Analysis of Radiopharmaceuticals [PDF]
Journal of AOAC INTERNATIONAL, 1971 Abstract Some of the activities of chemists engaged in evaluating and selecting analytical methodology for examination of radiopharmaceuticals and the criteria for assessment of their quality are described. Significant problems, as they relate to a regulatory analysis program, and tentative solutions to these problems are discussed ...
Max Jaffee, Leonard A. Ford
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Radiopharmaceuticals in cardiology [PDF]
Nuclear Medicine Review, 2012 Myocardial perfusion studies are among the most often performed investigations in Nuclear Medicine. However, the development of radiopharmaceuticals for cardiology is an emerging discipline and several other radiotracers have been proven to be useful.
Piotr Garnuszek, Renata Mikolajczak
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An Overview of PET Radiopharmaceuticals in Clinical Use: Regulatory, Quality and Pharmacopeia Monographs of the United States and Europe [PDF]
Nuclear Medicine Physics, 2018 Since 1976, more and more PET radiopharmaceuticals have been developed as the clinical introduction of [18F]FDG for various medical applications. However, few of them could be involved in routinely clinical use in hospitals partly because of restrictions
Ya-Yao Huang
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Radiopharmaceuticals for PET and SPECT Imaging: A Literature Review over the Last Decade
International Journal of Molecular Sciences, 2022 Positron emission tomography (PET) uses radioactive tracers and enables the functional imaging of several metabolic processes, blood flow measurements, regional chemical composition, and/or chemical absorption.
George Crișan +5 more
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Molecules, 2022 Therapeutic radiopharmaceuticals have been researched extensively in the last decade as a result of the growing research interest in personalized medicine to improve diagnostic accuracy and intensify intensive therapy while limiting side effects ...
H. A. Holik +5 more
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Cold Kit Labeling: The Future of 68Ga Radiopharmaceuticals?
Frontiers in Medicine, 2022 Over the last couple of decades, gallium-68 (68Ga) has gained a formidable interest for PET molecular imaging of various conditions, from cancer to infection, through cardiac pathologies or neuropathies.
N. Lepareur
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Theranostics, 2022 Rationale: Physiologically based pharmacokinetic (PBPK) and population pharmacokinetic (PK) modelling approaches are widely accepted in non-radiopharmaceutical drug development and research, while there is no major role for these approaches in ...
H. Siebinga +4 more
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Therapy with Radiopharmaceuticals [PDF]
Acta Oncologica, 2002 In an investigation by the Swedish Cancer Society, an expert group described the present status, critical issues and future aspects and potentials for each of nine major areas of radiation therapy research. The present report deals with therapy with radiopharmaceuticals.
Jörgen, Carlsson +4 more
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, 2022 Radiopharmaceuticals - Current Research for Better Diagnosis and Therapy discusses the importance of radiopharmaceuticals and their environmental, pharmaceutical, diagnostic, therapeutic, and research applications.
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