Results 101 to 110 of about 51,772 (325)
Brain MRI-to-PET Synthesis using 3D Convolutional Attention Networks [PDF]
arXiv, 2022 Accurate quantification of cerebral blood flow (CBF) is essential for the diagnosis and assessment of a wide range of neurological diseases. Positron emission tomography (PET) with radiolabeled water (15O-water) is considered the gold-standard for the measurement of CBF in humans. PET imaging, however, is not widely available because of its prohibitive
arxiv
Nuclear medicine in endocrine tumours [PDF]
, 2011 C
Peremans, Kathelijne +1 more
core +2 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Optimal dosing of oncological drugs is historically determined based on the “higher is better” paradigm. However, a paradigm shift in optimal dose selection has occurred in the development of new modalities, including molecularly targeted drugs, antibody drugs, and immunotherapies.
Hiroe Kitagaki +3 more
wiley +1 more source
Experimental setup for light-to-heat NIR conversion measurements of gold nano-particles\u2019 solutions [PDF]
, 2018 In recent years, there is a constantly increasing interest in the application of nanoparticles for cancer diagnosis and cancer therapy. In this respect, the most promising nano-objects at present are the gold nanoparticles. A very convenient and powerful
Bello, Michele +3 more
core +2 more sources
Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
International Journal of Cancer, EarlyView.Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano +6 more
wiley +1 more source
Radiopharmaceuticals in Acute Porphyria
Clinical Therapeutics, 2016 The acute porphyrias are a group of rare metabolic disorders of the heme biosynthetic pathway. Carriers of the acute porphyria gene are prone to potentially fatal acute attacks, which can be precipitated by drug exposure. It is therefore important to know whether a drug is safe for carriers of the acute porphyria gene.
Nanno Schreuder +2 more
openaire +3 more sources
Patient‐derived xenograft models in pan‐cancer: From bench to clinic
Interdisciplinary Medicine, EarlyView.Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li +5 more
wiley +1 more source
Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells
Journal of Applied Toxicology, EarlyView.ABSTRACT Human mesenchymal stem/stromal cells (hMSCs) can differentiate into mesoderm‐type cells, making them suitable candidates for tissue repair therapies. However, their relatively low frequency in adult tissue necessitates ex vivo expansion prior to regenerative medicine applications, and therefore, long‐term hMSC genetic stability during ...
Marc A. Beal +11 more
wiley +1 more source
Focal Spot, Spring/Summer 1983 [PDF]
, 1983 https://digitalcommons.wustl.edu/focal_spot_archives/1034/thumbnail ...
core +1 more source