Results 121 to 130 of about 78,818 (344)

Liposomal 188Rhenium Plus Macrophage Depletion Enhances Anti‐PD‐L1 Efficacy and B Cell Infiltration Against Lung Metastatic Cancer

Cancer Science, EarlyView.
This study demonstrates that combining liposomal Rhenium‐188 (Lipo‐Re188) with macrophage depletion and anti–PD‐L1 therapy enhances therapeutic efficacy against lung metastatic colon cancer. The triple therapy promotes B cell infiltration, restores T cell function, and suppresses MDSC, creating a tumor‐suppressive immune microenvironment.
Shin‐Yi Liu, Liang‐Ting Lin, Chih‐Hsien Chang, Yu‐Jen Chen   +3 more
wiley   +1 more source

Recent Advances and Strategies in the Development of Therapeutic Radiopharmaceuticals

Journal of Isotopes
Therapeutic radiopharmaceuticals can be employed in the treatment of various tumor diseases，and their global market share is likely to witness an explosive growth in the recent decade.
Mianxue LIU, Yueqi LIANG, Min HUANG, Hao CHEN, Yuxi LUO, Jian ZHAO, Lijuan CHEN, Hongtao JIN, Qian CHEN   +8 more
doaj   +1 more source

SINTESIS DAN KARAKTERISASI NUKLEOTIDA BERTANDA [α-32P]ATP

Jurnal Riset Kimia, 2019
The utilization of nuclear technology in health sector with molecular techniques is increasingly developed today, especially in Indonesia.  One of which is nucleotide compound marked with [α-32P]ATP, this compound has been used as tracer for ...
Wira Yusril Rahman, Endang Sarmini, H. Herlina, A. Abidin, T. Triyanto, H. Hambali, Santi Nurbaiti   +6 more
doaj   +1 more source

Positron emission tomography [PDF]

, 2006
Positron Emission Tomography (PET) is a method for measuring biochemical and physiological processes in vivo in a quantitative way by using radiopharmaceuticals labelled with positron emitting radionuclides such as 11C, 13N, 15O and 18F and by measuring ...
Paans, A M J
core   +1 more source

Obesity is associated with increased brain glucose uptake and activity but not neuroinflammation (TSPO availability) in monozygotic twin pairs discordant for BMI—Exercise training reverses increased brain activity

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Obesity is associated with increased insulin‐stimulated brain glucose uptake (BGU) which is opposite to decreased GU observed in peripheral tissues. Increased BGU was shown to be reversed by weight loss and exercise training, but the mechanisms remain unknown.
Jaakko Hentilä, Jouni Tuisku, Ronja Ojala, Lihua Sun, Martin S. Lietzén, Heidi Virtanen, Riikka Lautamäki, Kalle Koskensalo, Lauri Nummenmaa, Eliisa Löyttyniemi, Semi Helin, Kirsi H. Pietiläinen, Jaakko Kaprio, Leo Lahti, Tarja Malm, Juha O. Rinne, Jarna C. Hannukainen   +16 more
wiley   +1 more source

Functional brain imaging : a brief overview of imaging techniques and their use in human and canine anxiety research [PDF]

, 2011
When used in combination with specific radioactive markers, functional imaging modalities such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) enable the visualization of several neurotransmitter receptors and
Audenaert, Kurt, De Meester, Rudy, Dobbeleir, André, Peremans, Kathelijne, van Bree, Henri, Vandermeulen, Eva, Vermeire, Simon   +6 more
core  

Radiopharmaceuticals for diagnosis in nuclear medicine: a short review

Eclética Química Journal, 2019
Radiopharmaceuticals are radioactive compounds which have a bound radionuclide in their structure, whose purpose is directing the radionuclide to a location to be treated or to obtain images.
Filipe Boccato Payolla, A. Massabni, C. Orvig   +2 more
semanticscholar   +1 more source

Injuries to the superficial digital flexor tendon branches: Clinical presentation, diagnostic features and outcome

Equine Veterinary Education, EarlyView.
Summary Background Injury of the superficial digital flexor tendon (SDFT) branch is uncommon and the response to different treatments has not been reported. Objectives The aim of this study was to describe the clinical presentation, diagnostic features, treatment methods, and outcome of horses diagnosed with SDFT branch injuries.
P. Spiesshofer, V. O'Hara, K. S. Garrett, R. K. Smith   +3 more
wiley   +1 more source

Expanding a peptide-covalent probe hybrid for PET imaging of S. aureus driven focal infections

EJNMMI Radiopharmacy and Chemistry
Background The urgent demand for innovative theranostic strategies to combat bacterial resistance to antibiotics is evident, with substantial implications for global health. Rapid diagnosis of life-threatening infections can expedite treatment, improving
Jyotsna Bhatt Mitra, Saurav Chatterjee, Anuj Kumar, Elina Khatoon, Ashok Chandak, Sutapa Rakshit, Anupam Bandyopadhyay, Archana Mukherjee   +7 more
doaj   +1 more source

Discovery and evaluation of a novel 18F-labeled vasopressin 1a receptor PET ligand with peripheral binding specificity

Acta Pharmaceutica Sinica B
The arginine-vasopressin (AVP) hormone plays a pivotal role in regulating various physiological processes, such as hormone secretion, cardiovascular modulation, and social behavior.
Junqi Hu, Yinlong Li, Chenchen Dong, Huiyi Wei, Kai Liao, Junjie Wei, Chunyu Zhao, Ahmad Chaudhary, Jiahui Chen, Hao Xu, Ke Zhong, Steven H. Liang, Lu Wang, Weijian Ye   +13 more
doaj   +1 more source