Results 21 to 30 of about 54,698 (337)

Albumin Binder–Conjugated Fibroblast Activation Protein Inhibitor Radiopharmaceuticals for Cancer Therapy

open access: yesJournal of Nuclear Medicine, 2021
Visual Abstract Fibroblast activation protein (FAP) has become an attractive target for diagnosis and therapy, and a series of FAP inhibitor (FAPI)–based radiotracers has been developed and had excellent performance for diagnosis outcomes in clinical ...
Mengxin Xu   +5 more
semanticscholar   +1 more source

Synthesis and Evaluation of Novel Norfloxacin Isonitrile 99mTc Complexes as Potential Bacterial Infection Imaging Agents

open access: yesPharmaceutics, 2021
To develop potential technetium-99m single-photon emission computed tomography (SPECT) imaging agents for bacterial infection imaging, the novel norfloxacin isonitrile derivatives CN4NF and CN5NF were synthesized and radiolabeled with a [99mTc][Tc(I ...
Si’an Fang   +6 more
doaj   +1 more source

Recent Applications of Ambient Ionization Mass Spectrometry for Environmental Pollutant Detection [PDF]

open access: yesZhipu Xuebao, 2023
Along with the industrial development and human society progress, large number of pollutants have been discharged to induce the environmental pollution, which have attracted global attentions.
QIN Jing-yi, OUYANG Jin, NA Na
doaj   +1 more source

Artificial intelligence and the future of diagnostic and therapeutic radiopharmaceutical development: in Silico smart molecular design [PDF]

open access: yes, 2021
Novel diagnostic and therapeutic radiopharmaceuticals are increasingly becoming a central part of personalized medicine. Continued innovation in the development of new radiopharmaceuticals is key to sustained growth and advancement of precision medicine.
arxiv   +1 more source

Expanding Theranostic Radiopharmaceuticals for Tumor Diagnosis and Therapy

open access: yesPharmaceuticals, 2021
Radioligand theranostics (RT) in oncology use cancer-type specific biomarkers and molecular imaging (MI), including positron emission tomography (PET), single-photon emission computed tomography (SPECT) and planar scintigraphy, for patient diagnosis ...
Cristina Barca   +10 more
semanticscholar   +1 more source

Hydroxypyridinones as a Very Promising Platform for Targeted Diagnostic and Therapeutic Radiopharmaceuticals

open access: yesMolecules, 2021
Hydroxypyridinones (HOPOs) have been used in the chelation therapy of iron and actinide metals. Their application in metal-based radiopharmaceuticals has also been increasing in recent years.
Xu Zhou, Linlin Dong, Langtao Shen
doaj   +1 more source

PET with Different Radiopharmaceuticals in Neuroendocrine Neoplasms: An Umbrella Review of Published Meta-Analyses

open access: yesCancers, 2021
Simple Summary Functional imaging methods and, in particular, positron emission tomography (PET) using several radiopharmaceuticals may play a pivotal role in patients with neuroendocrine neoplasms including neuroendocrine tumors (NETs) located in ...
G. Treglia   +6 more
semanticscholar   +1 more source

Current status and future perspective of radiopharmaceuticals in China

open access: yesEuropean Journal of Nuclear Medicine and Molecular Imaging, 2021
Radiopharmaceuticals are essential components of nuclear medicine and serve as one of the cornerstones of molecular imaging and precision medicine. They provide new means and approaches for early diagnosis and treatment of diseases.
Ji Hu, Hongyu Li, Yanying Sui, Jin Du
semanticscholar   +1 more source

Synthesis and Evaluation of 99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

open access: yesPharmaceuticals, 2023
When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms.
Qing Ruan   +6 more
doaj   +1 more source

A quantitative proteomics analysis for small molecule Stemazole’s effect on human neural stem cells

open access: yesProteome Science, 2020
Background Stemazole is a novel small molecule that has been suggested to have the ability to protect multiple stem cells. The proliferation-promoting activity and promising neuroprotective effects of stemazole make it a prospective drug for ...
Huajun Li   +5 more
doaj   +1 more source

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