Advances in the Chemistry of Astatine and Implications for the Development of Radiopharmaceuticals.
ConspectusAstatine (At) is the rarest on Earth of all naturally occurring elements, situated below iodine in the periodic table. While only short-lived isotopes (t1/2 ≤ 8.1 h) are known, 211At is the object of growing attention due to its emission of ...
F. Guérard +6 more
semanticscholar +1 more source
Targeted radiotherapy of neuroblastoma: future directions [PDF]
No abstract ...
Gaze, Mark N. +4 more
core +2 more sources
A quantitative proteomics analysis for small molecule Stemazole’s effect on human neural stem cells
Background Stemazole is a novel small molecule that has been suggested to have the ability to protect multiple stem cells. The proliferation-promoting activity and promising neuroprotective effects of stemazole make it a prospective drug for ...
Huajun Li +5 more
doaj +1 more source
Development Strategy for Innovation System of Radiopharmaceuticals in China
Nuclear medicine plays an irreplaceable role in the diagnosis, therapy, and prognosis of various diseases. Radiopharmaceuticals are the cornerstone of nuclear medicine; their systematic development could accelerate the innovation and clinical application
Peng Shuming +5 more
doaj +1 more source
Influence of Storage Temperature on Radiochemical Purity of 99mTc-Radiopharmaceuticals [PDF]
The influence of effective room temperature on the radiochemical purity of 99mTc-radiopharmaceuticals was reported. This study was born from the observation that in the isolators used for the preparation of the 99mTc-radiopharmaceuticals the ...
Bartolomei, Mirco +14 more
core +2 more sources
Effect of an extract of Centella asiatica on the biodistribution of sodium pertechnetate (Na99mTcO4) and on the fixation of radioactivity on blood constituents [PDF]
This study evaluates the effects of an acute treatment with a Centella asiatica (CA) extract on the biodistribution of the radiopharmaceutical Na99mTcO4 and on the fixation of technetium-99m on blood constituents. Wistar rats were treated with CA extract
Adenilson de Souza da Fonseca +22 more
core +4 more sources
Pharmacovigilance in radiopharmaceuticals
Indian Pharmacopoeia Commission is Committed for maintaining the standards of drugs including Radiopharmaceuticals (RPs) by publishing Indian Pharmacopoeia. These RPs are being used in India for diagnostic or therapeutic purpose. RPs though contain relatively small quantities of active ingredient and administered in small volumes could cause some ...
Rakesh Kumar +4 more
openaire +4 more sources
Radiopharmaceuticals in cardiology
Myocardial perfusion studies are among the most often performed investigations in Nuclear Medicine. However, the development of radiopharmaceuticals for cardiology is an emerging discipline and several other radiotracers have been proven to be useful.
Piotr Garnuszek, Renata Mikolajczak
openaire +4 more sources
Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. [PDF]
OBJECTIVE: The authors have conjugated chelating agents (DOTA and NODAGA) with a peptide (pituitary adenylate cyclase-activating peptide [PACAP] analogue) that has a high affinity for VPAC1 receptors expressed on cancer cells.
Chen, Chang-Po +6 more
core +2 more sources
Simple Summary Functional imaging methods and, in particular, positron emission tomography (PET) using several radiopharmaceuticals may play a pivotal role in patients with neuroendocrine neoplasms including neuroendocrine tumors (NETs) located in ...
G. Treglia +6 more
semanticscholar +1 more source

