Results 51 to 60 of about 78,818 (344)

EANM guideline on the validation of analytical methods for radiopharmaceuticals

EJNMMI Radiopharmacy and Chemistry, 2020
Background To fulfil good manufacturing requirements, analytical methods for the analysis of pharmaceuticals for human and vetinary use must be validated.
N. Gillings, S. Todde, M. Béhé, C. Decristoforo, P. Elsinga, Valentina Ferrari, Olaug Hjelstuen, P. Peitl, J. Koziorowski, P. Laverman, T. Mindt, M. Ocak, M. Patt   +12 more
semanticscholar   +1 more source

Bivalent non-human gal-α1-3-gal glycan epitopes in the Fc region of a monoclonal antibody model can be recognized by anti-Gal-α1-3-Gal IgE antibodies

mAbs, 2023
Monoclonal antibody (mAb) production using non-human cells can introduce non-human glycan epitopes including terminal galactosyl-α1–3-galactose (α1–3-Gal) moieties. Cetuximab is a commercial mAb associated with causing anaphylaxis in some patients due to
Grayson Hatfield, Lioudmila Tepliakova, Jessica Tran, Huixin Lu, Michel Gilbert, Roger Y. Tam   +5 more
doaj   +1 more source

Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes. [PDF]

, 2018
Oxidative stress is a critical feature of several common neurologic disorders. The brain is well adapted to neutralize oxidative injury by maintaining a high steady-state concentration of small-molecule intracellular antioxidants including glutathione in
Carroll, Valerie N, Flavell, Robert R, Keshari, Kayvan R, Kurhanewicz, John, Mutch, Christopher A, Qin, Hecong, Sriram, Renuka, Villanueva-Meyer, Javier E, von Morze, Cornelius, Wang, Zhen Jane, Wilson, David M   +10 more
core   +1 more source

Review of Adverse Reactions Associated with the Use of Common Diagnostic Radiopharmaceuticals

Indian Journal of Nuclear Medicine, 2021
Radiopharmaceuticals are used in the diagnosis and management of various diseases. There are several reports of adverse reactions related to the use of radiopharmaceuticals, though it is not as common as conventional drugs.
B. Meher, K. Agrawal, G. Gnanasegaran
semanticscholar   +1 more source

Nuclear medicine as a tool for diagnosis and targeted cancer therapy

Бюллетень сибирской медицины, 2018
The main trends and prospects of development of nuclear medicine, problems and possible ways of their solution are considered in the article. The main scientific directions in the development of radiopharmaceuticals for the diagnosis and radionuclide ...
V. I. Chernov, A. A. Medvedeva, I. G. Sinilkin, R. V. Zelchan, O. D. Bragina, E. L. Choynzonov   +5 more
doaj   +1 more source

Research Progress of Metal-Based Radiopharmaceuticals Targeting Somatostatin Receptor

He huaxue yu fangshe huaxue, 2023
Neuroendocrine tumors(NETs) are a group of heterogeneous tumors originating from neuroendocrine cells. They can occur anywhere in the body, most commonly in the digestive tract, pancreas, and lungs.
QIN Xiang-yu, SHEN Lang-tao
doaj   +1 more source

AAPM medical physics practice guideline 10.a.: Scope of practice for clinical medical physics. [PDF]

, 2018
The American Association of Physicists in Medicine (AAPM) is a nonprofit professional society whose primary purposes are to advance the science, education, and professional practice of medical physics.
Anthony Seibert, J, Baird, Christopher T, Clements, Jessica B, de Boer, Steven F, Fairobent, Lynne A, Fisher, Tyler, Goodwin, James H, Gress, Dustin A, Johnson, Jennifer Lynn, Kolsky, Kathryn L, Mageras, Gig S, Marsh, Rebecca M, Martin, Melissa C, Parker, Brent, Pavord, Daniel C, Schell, Michael C, Stevens, Donna M, Tarver, Russell B, Waite-Jones, Christopher G, Wingreen, Nicholai   +19 more
core   +1 more source

Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation

European Journal of Medical Research
This review article explores the dynamic field of radiopharmaceuticals, where innovative developments arise from combining radioisotopes and pharmaceuticals, opening up exciting therapeutic possibilities.
Shivang Dhoundiyal, Shriyansh Srivastava, Sachin Kumar, Gaaminepreet Singh, Sumel Ashique, Radheshyam Pal, Neeraj Mishra, F. Taghizadeh-Hesary   +7 more
semanticscholar   +1 more source

Carrier systems of radiopharmaceuticals and the application in cancer therapy

Cell Death Discovery
Radiopharmaceuticals play a vital role in cancer therapy. The carrier of radiopharmaceuticals can precisely locate and guide radionuclides to the target, where radionuclides kill surrounding tumor cells.
Taotao Zhang, H. Lei, Xiaohua Chen, Zhihui Dou, Boyi Yu, Wei Su, Wei Wang, Xiaodong Jin, T. Katsube, Bing Wang, Hong Zhang, Qiang Li, C. Di   +12 more
semanticscholar   +1 more source

Optimal clinical protocols for total-body 18F-FDG PET/CT examination under different activity administration plans

EJNMMI Physics, 2023
Background Highly sensitive digital total-body PET/CT scanners (uEXPLORER) have great potential for clinical applications and fundamental research. Given their increasing sensitivity, low-dose scanning or snapshot imaging is now possible in clinics ...
Yanchao Huang, Meng Wang, Li Jiang, Lijuan Wang, Li Chen, Qiaoyu Wang, Jiatai Feng, Jingyi Wang, Wanbang Xu, Hubing Wu, Yanjiang Han   +10 more
doaj   +1 more source