Results 71 to 80 of about 78,818 (344)

Applications of carbon dots on tumour theranostics

View, 2021
Carbon dots (CDs) have been extensively investigated as prime candidates for developing tumour theranostic platform due to their tunable fluorescence emission and excitation, good photostability, high water solubility and biocompatibility.
Hao Wu, Wen Su, Huimin Xu, Yang Zhang, Yunchao Li, Xiaohong Li, Louzhen Fan   +6 more
doaj   +1 more source

166Dy/166Ho-labeled porous hydroxyapatite microparticles for treatment of inflammatory joint diseases – Exploring the advantages of in vivo generator

Scientific Reports
Holmium-166 [T½ = 26.8 h, Eβ − (max) = 1.74 MeV (48.7%) and 1.85 MeV (50.0%); Eγ = 80.6 keV (10.6%)] is one of the most promising radionuclides in radiation synovectomy (RSV) for the treatment of inflammatory joint diseases, especially of large joints ...
Sourav Patra, Khajan Singh, Avik Chakraborty, Shahiralam Khan Mohammed, Sutapa Rakshit, Rubel Chakravarty, Sudipta Chakraborty   +6 more
doaj   +1 more source

Radiosynthesis and in vivo evaluation of 11C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors

EJNMMI Radiopharmacy and Chemistry, 2019
Background Neuropeptide Y (NPY) has been implicated in a wide variety of physiological processes, including feeding, learning, memory, emotion, cardiovascular homeostasis, hormone secretion, and circadian rhythms.
Kazunori Kawamura, Wakana Mori, Masayuki Fujinaga, Tomoteru Yamasaki, Yiding Zhang, Hidekatsu Wakizaka, Akiko Hatori, Lin Xie, Katsushi Kumata, Takayuki Ohkubo, Yusuke Kurihara, Masanao Ogawa, Nobuki Nengaki, Ming-Rong Zhang   +13 more
doaj   +1 more source

A Quantitative Proteomic Approach Explores the Possible Mechanisms by Which the Small Molecule Stemazole Promotes the Survival of Human Neural Stem Cells

Brain Sciences, 2022
Neurodegenerative disorders have become a serious healthcare problem worldwide and there is no efficacious cure. However, regulating the fate of stem cells is an effective way to treat these neurological diseases. In previous work, stemazole was reported
Mingzhu Chen, Yizi Zhu, Huajun Li, Yubo Zhang, Mei Han   +4 more
doaj   +1 more source

Radiolabelled Cyclodextrins for the Positron Emission Tomography Imaging of Breast Cancer: Preclinical Perspectives. [PDF]

Clin Transl Sci
ABSTRACT Given the increasing incidence and mortality of breast cancer, the development of target‐specific imaging probes for early disease detection seems straightforward. Prostaglandin E2 (PGE2) and its receptors have a crucial role in tumor angiogenesis; therefore, radiolabelled cyclodextrins targeting such biomolecules may serve as selective ...
Sass T, Szabó JP, Dienes RA, Árkosy P, Opposits G, Jószai I, Fekete A, Fenyvesi F, Hajdu I, Trencsényi G, Képes Z.   +10 more
europepmc   +2 more sources

Comparison of technetium-99m IgG with technetium-99m red blood cells labeling in cardiac blood-pool scintigraphy: A preliminary study [PDF]

, 2011
This first clinical prospective study was conducted to use of technetium-99m immunoglobulin G (99mTc-IgG) as compared with autologous 99mTc-red blood cells (RBC) in gated blood pool ventriculography.
Amini, A., Ansari, M., Asli, I.N., Assadi, M., Barekat, M., Jallalat, S., Javadi, H., Semnani, S.   +7 more
core  

Development of 225Ac Radiopharmaceuticals: TRIUMF Perspectives and Experiences

Current Radiopharmaceuticals, 2018
Background: The development of radiopharmaceuticals containing 225Ac for targeted alpha therapy is an active area of academic and commercial research worldwide.
A. Robertson, C. Ramogida, P. Schaffer, V. Radchenko   +3 more
semanticscholar   +1 more source

Advances in radiopharmaceuticals for cancer radiotheranostics: CCK2R targeting as a paradigm for translational innovation

Cancer Communications, EarlyView.
Abstract Radiopharmaceuticals are reshaping the landscape of cancer therapy, offering a unique theranostic advantage that is becoming increasingly central to precision medicine. By labeling the same molecular scaffold with different radionuclides, these agents enable seamless integration of diagnostic imaging and targeted therapy.
Jing Li, Xuejun Wen, Rebeka Rita Reszegi, Hemavarshini Kamalrhaj, Wolfgang J. Parak, Xiaoyuan Chen, Jingjing Zhang   +6 more
wiley   +1 more source

Activatable theranostic prodrug scaffold with tunable drug release rate for sequential photodynamic and chemotherapy

Smart Molecules
Glutathione (GSH)‐activated prodrugs are promising for overcoming the limitations of conventional anti‐tumor drugs. However, current GSH‐responsive disulfide groups exhibit unregulated reactivity, making it impossible to precisely control the drug ...
Si‐Yu Wang, Ying‐Hao Pan, Yu‐Chen Qu, Xiao‐Xiao Chen, Na Shao, Li‐Ya Niu, Qing‐Zheng Yang   +6 more
doaj   +1 more source

Nuclear Medicine in Cancer Diagnosis and Therapy [PDF]

, 2017
Early cancer diagnosis remains one of the most actual problems of medicine, since it allows using the most effective methods of cancer treating. Unlike most diagnostic methods used in oncology, the methods of nuclear medicine allow assessing not so much ...
Bragina, Olga Dmitrievna, Chernov, Vladimir Ivanovich, Medvedeva, Anna Aleksndrovna, Sinilkin, Ivan Gennadjevich, Zeltchan, R.   +4 more
core   +1 more source