Results 81 to 90 of about 54,698 (337)

Preclinical evaluation of [18F]FP-CIT, the radiotracer targeting dopamine transporter for diagnosing Parkinson’s disease: pharmacokinetic and efficacy analysis

open access: yesEJNMMI Research
Background N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (FP-CIT), the representative cocaine derivative used in dopamine transporter imaging, is a promising biomarker, as it reflects the severity of Parkinson’s disease (PD).
Jae Hun Ahn   +9 more
doaj   +1 more source

Feasibility study of the positronium imaging with the J-PET tomograph [PDF]

open access: yes, 2018
A detection system of the conventional PET tomograph is set-up to record data from e+ e- annihilation into two photons with energy of 511 keV, and it gives information on the density distribution of a radiopharmaceutical in the body of the object. In this paper we explore the possibility of performing the three gamma photons imaging based on ortho ...
arxiv   +1 more source

Characterization in Geant4 of different PET configurations [PDF]

open access: yesarXiv, 2023
Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation in PET as well as improvement in electronic detectors (e.g., SiPMs) and signal processing, makes the field of PET
arxiv  

TP53‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah   +2 more
wiley   +1 more source

Flux crystal growth of Ba2[(UO2)2Ti2O8]: Structures, spectroscopies and implications

open access: yesJournal of the American Ceramic Society, Volume 106, Issue 2, Page 1381-1390, February 2023., 2023
We report a flux crystal growth of Ba2[(UO2)2Ti2O8], and subsequent structural and spectroscopic studies using multiple techniques including synchrotron single crystal X‐ray diffraction and X‐ray absorption near‐edge structure spectroscopy. In addition, its vibrational modes and thermal stability were investigated.
Kimbal T. Lu   +5 more
wiley   +1 more source

SINTESIS DAN KARAKTERISASI NUKLEOTIDA BERTANDA [α-32P]ATP

open access: yesJurnal Riset Kimia, 2019
The utilization of nuclear technology in health sector with molecular techniques is increasingly developed today, especially in Indonesia.  One of which is nucleotide compound marked with [α-32P]ATP, this compound has been used as tracer for ...
Wira Yusril Rahman   +6 more
doaj   +1 more source

Letter: Radiopharmaceuticals in breastfeeding [PDF]

open access: yesAustralian Prescriber, 2016
In the article on drugs in breastfeeding,1 I was dismayed at the inclusion of ‘radiopharmaceuticals’ in the table of drugs contraindicated in breastfeeding. There was little elaboration within the article as to the reason for this. The other drugs listed have sufficient evidence of the potential for serious adverse effects to the infant.
openaire   +3 more sources

Production Of 11C‐Labeled Amides Via “In‐Loop” 11C‐Carbonylation

open access: yesAsian Journal of Organic Chemistry, EarlyView.
The current work utilizes carbon‐11 labelled aroyl dimethylaminopyridinium salts in a two‐step in‐loop carbonylative cross‐coupling reaction of aryl halides with [¹¹C]CO yielding a diverse range of carbon‐11 labelled primary benzamides with good to excellent yields.
Tanpreet Kaur   +3 more
wiley   +1 more source

Rhenium-188 Labeled Radiopharmaceuticals: Current Clinical Applications in Oncology and Promising Perspectives

open access: yesFrontiers in Medicine, 2019
Rhenium-188 (188Re) is a high energy beta-emitting radioisotope with a short 16.9 h physical half-life, which has been shown to be a very attractive candidate for use in therapeutic nuclear medicine.
N. Lepareur   +9 more
semanticscholar   +1 more source

Premenopausal bilateral oophorectomy and Alzheimer's disease imaging biomarkers later in life

open access: yesAlzheimer's &Dementia, EarlyView.
Abstract INTRODUCTION Premenopausal bilateral oophorectomy (PBO) before the age of 46 years is associated with an increased risk of dementia. We investigated the long‐term effects of PBO performed before age 50 years on amyloid beta (Aβ), tau, and neurodegeneration imaging biomarkers of Alzheimer's disease (AD).
Kejal Kantarci   +13 more
wiley   +1 more source

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