Results 81 to 90 of about 51,772 (325)

AAPM medical physics practice guideline 10.a.: Scope of practice for clinical medical physics. [PDF]

open access: yes, 2018
The American Association of Physicists in Medicine (AAPM) is a nonprofit professional society whose primary purposes are to advance the science, education, and professional practice of medical physics.
Anthony Seibert, J   +19 more
core   +1 more source

Mono‐Ethyl‐Phosphonates: Functional Group Masking Strategy to Stabilize and Optimize the Pharmacokinetics of Rare Earth Radiochelates

open access: yesChemistryEurope, EarlyView.
Prodrug strategies are used to enhance the pharmacokinetics of small molecule drugs. Here, this approach to rare earth coordination complexes is adopted with applications as diagnostic and therapeutic radiopharmaceuticals: a mono‐ethyl‐phosphonate polyazamacrocyclic chelator for 44Sc and 177Lu reduces blood and bone uptake.
Jennifer N. Whetter   +8 more
wiley   +1 more source

Novel [99mTcN]2+ Labeled EGFR Inhibitors as Potential Radiotracers for Single Photon Emission Computed Tomography (SPECT) Tumor Imaging

open access: yesMolecules, 2014
The epidermal growth factor receptor (EGFR) is overexpressed in many cancers, including breast, ovarian, endometrial and non-small cell lung cancer. An EGFR-specific imaging agent could facilitate clinical evaluation of primary tumors or metastases.
Mingxia Zhao   +5 more
doaj   +1 more source

Comparison of technetium-99m IgG with technetium-99m red blood cells labeling in cardiac blood-pool scintigraphy: A preliminary study [PDF]

open access: yes, 2011
This first clinical prospective study was conducted to use of technetium-99m immunoglobulin G (99mTc-IgG) as compared with autologous 99mTc-red blood cells (RBC) in gated blood pool ventriculography.
Amini, A.   +7 more
core  

The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort. [PDF]

open access: yes, 2018
ObjectiveThe Parkinson's Progression Markers Initiative (PPMI) is an observational, international study designed to establish biomarker-defined cohorts and identify clinical, imaging, genetic, and biospecimen Parkinson's disease (PD) progression markers ...
Arnedo, Vanessa   +26 more
core   +2 more sources

From Desferrioxamine B Umpolung to an Enantiopure Bifunctional Chelator for 89Zr‐immunoPET

open access: yesChemistry – A European Journal, EarlyView.
Functional group transformations were performed at the pendent amine residue of desferrioxamine B (DFO), the commercial siderophore used in various medical applications, including iron decorporation, antibiotic development, and molecular imaging.
Laurie Zujew   +2 more
wiley   +1 more source

Preparation and Bioevaluation of Novel 99mTc-Labeled Complexes with a 2-Nitroimidazole HYNIC Derivative for Imaging Tumor Hypoxia

open access: yesPharmaceuticals, 2021
To develop novel 99mTc-labeled single-photon emission computed tomography (SPECT) radiotracers for imaging hypoxia, a novel HYNICNM ligand (6-hydrazinonicotinamide (HYNIC) 2-nitroimidazole derivative) was designed and synthesized.
Qing Ruan   +4 more
doaj   +1 more source

Studies on ToF-PET using Cherenkov radiation [PDF]

open access: yes, 2015
La tomografia ad emissione di positroni (PET) è una tecnica di imaging di medicina nucleare, utilizzata oggi diffusamente in ambito clinico. Essa fornisce immagini e informazioni fisiologiche dei processi funzionali all’interno del corpo.
La Rosa, Francesco
core  

Radioisotopic purity and imaging properties of cyclotron-produced 99mTc using direct 100Mo(p,2n) reaction [PDF]

open access: yes, 2018
Evaluation of the radioisotopic purity of technetium-99m (99mTc) produced in GBq amounts by proton bombardment of enriched molibdenum-100 (100Mo) metallic targets at low proton energies (i.e. within 15\u201320 MeV) is conducted.
Bello, M.   +24 more
core   +1 more source

Fluorescent Deferoxamine Complexes of Cu(II) and Zr(IV): Insights in the Development of Dual Imaging Probes

open access: yesChemistry – A European Journal, EarlyView.
The insertion of a fluorescent coumarin unit by using a lysine‐based linker on deferoxamine leads to a chelating agent (DFOKC), whose Cu(II) and Zr(IV) complexes can be used for both optical imaging and positron emission tomography. DFOKC shows increased binding ability for Cu(II) and Zr(II) and improved tumor cell internalization via pinocytosis ...
Yschtar Tecla Simonini Steiner   +8 more
wiley   +1 more source

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