Results 31 to 40 of about 6,121 (195)

Editorial - EJNMMI radiopharmacy and chemistry [PDF]

open access: yesEJNMMI Radiopharmacy and Chemistry, 2016
Philip H. Elsinga
doaj   +3 more sources

New bioconjugated rhenium carbonyls by transmetalation reaction with zinc derivatives [PDF]

open access: yes, 2012
The transmetallation reaction between zinc dithiocarbamates and rhenium carbonyls has been used as a new strategy to link biomolecules to transition metals.
Alvarez-Larena, Angel   +5 more
core   +2 more sources

Bioorganometallic Technetium and Rhenium Chemistry: Fundamentals for Applications

open access: yesCHIMIA, 2020
Due to its long half-life of 2.111×105 y, technetium, i.e. 99Tc, offers the excellent opportunity of combining fundamental and ' classical ' organometallic or coordination chemistry with all methodologies of radiochemistry.
Roger Alberto   +2 more
doaj   +1 more source

Comparison of Post-injection Site Pain Between Technetium Sulfur Colloid and Technetium Tilmanocept in Breast Cancer Patients Undergoing Sentinel Lymph Node Biopsy. [PDF]

open access: yes, 2015
BackgroundNo prior studies have examined injection pain associated with Technetium-99m Tilmanocept (TcTM).MethodsThis was a randomized, double-blinded study comparing postinjection site pain between filtered Technetium Sulfur Colloid (fTcSC) and TcTM in ...
Baker, Jennifer L   +6 more
core   +1 more source

Carbidopa Capsules for Insulinoma Diagnostic: Compounding and Stability Study

open access: yesPharmaceutical Technology in Hospital Pharmacy, 2020
Carbidopa is a drug mainly used to treat Parkinson’s disease. Associations with levodopa or with levodopa/entacapone are commercialized, but there is no oral formulation of carbidopa alone available in Europe.
Curti Christophe   +6 more
doaj   +1 more source

Targeted Radiotherapeutics from 'Bench-to-Bedside'

open access: yesCHIMIA, 2020
he concept of targeted radionuclide therapy (TRT) is the accurate and efficient delivery of radiation to disseminated cancer lesions while minimizing damage to healthy tissue and organs.
Cristina Müller   +4 more
doaj   +1 more source

Rapid, efficient, and economical synthesis of PET tracers in a droplet microreactor: application to O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET). [PDF]

open access: yes, 2019
BackgroundConventional scale production of small batches of PET tracers (e.g. for preclinical imaging) is an inefficient use of resources. Using O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET), we demonstrate that simple microvolume radiosynthesis ...
Chen, Bao Ying   +5 more
core   +1 more source

Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. [PDF]

open access: yes, 2016
OBJECTIVE: The authors have conjugated chelating agents (DOTA and NODAGA) with a peptide (pituitary adenylate cyclase-activating peptide [PACAP] analogue) that has a high affinity for VPAC1 receptors expressed on cancer cells.
Chen, Chang-Po   +6 more
core   +2 more sources

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

open access: yesAngewandte Chemie International Edition, EarlyView.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann   +23 more
wiley   +1 more source

Optimized, automated and cGMP-compliant synthesis of the HER2 targeting [68Ga]Ga-ABY-025 tracer

open access: yesEJNMMI Radiopharmacy and Chemistry, 2023
Background The Affibody molecule, ABY-025, has demonstrated utility to detect human epidermal growth factor receptor 2 (HER2) in vivo, either radiolabelled with indium-111 (111In) or gallium-68 (68Ga).
Emma Jussing   +10 more
doaj   +1 more source

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