Results 31 to 40 of about 4,269 (177)

Metastatic Spread in Prostate Cancer Patients Influencing Radiotherapy Response

Frontiers in Oncology, 2021
Radiotherapy and surgery are curative treatment options for localized prostate cancer (PCa) with a 5-year survival rate of nearly 100%. Once PCa cells spread into distant organs, such as bone, the overall survival rate of patients drops dramatically. The
Daria Klusa, Daria Klusa, Fabian Lohaus, Giulia Furesi, Martina Rauner, Martina Benešová, Mechthild Krause, Mechthild Krause, Mechthild Krause, Mechthild Krause, Ina Kurth, Claudia Peitzsch, Claudia Peitzsch, Claudia Peitzsch   +13 more
doaj   +1 more source

Central Nuclear Pharmacy, Our lost Treasure [PDF]

Egyptian Journal of Nuclear Medicine, 2012
Commercial central radiopharmacy is a mature and practical concept in the developed countries long time ago. However, in the developing ones where its importance and feasibility is much more valid, this concept is not yet well established.
Tamir Bayomy
doaj   +1 more source

The Use of Virtual Reality as an Aid Tool in the Implementation of a Radiopharmacy Center in a Nuclear Medicine Service

Brazilian Journal of Radiation Sciences, 2023
The preparations of radiopharmaceuticals must follow the parameters of quality, efficacy, and safety (pharmaceutical and nuclear), complying with all the requirements established in good manufacturing practices, guaranteed by the physical structure ...
Daniel Mol Machado, Mônica de Assis, Antonio Carlos de Abreu Mól, Andre Cotelli do Espirito Santo, Julio Suita, Celso Marcelo Lapa   +5 more
doaj   +1 more source

How to validate radiopharmaceuticals management software?

Pharmaceutical Technology in Hospital Pharmacy, 2020
In the context of securing medication management systems (MMS) in healthcare habilities, implementation of an electronic MMS is a priority area of work.
Léa De Neef, Damien Peyronnet, Blondeel-Gomes Sandy   +2 more
doaj   +1 more source

Optimization of Automated Radiosynthesis of Gallium-68-Labeled PSMA11 with Two [⁶⁸Ge]Ge/[⁶⁸Ga]Ga Generators: Fractional Elution or Prepurification?

Pharmaceuticals, 2023
Prostate cancer is one of the most common forms of cancer in men. An imaging technique for its diagnosis is [68Ga]-prostate-specific membrane antigen ([68Ga]Ga-PSMA-11) positron emission tomography (PET).
Flore Durieux, Bérengère Dekyndt, Jean-François Legrand, Antoine Rogeau, Emmanuel Malek, Franck Semah, Pascal Odou   +6 more
doaj   +1 more source

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann, Constanze C. Schmies, Georg Wilhelm Rolshoven, Mirko Scortichini, Stefan Wagner, Andreas Isaak, Riham M. Idris, Jennifer Dabel, Lucie Grey, Karolina Losenkova, Susanne Moschütz, Haneen Al Hroub, Antje Keim, Sandra Höppner, Jouko Sandholm, Pia Boström, Maija Hollmén, Norbert Sträter, Sven Hermann, Gennady G. Yegutkin, Kenneth A. Jacobson, Sonja Schelhaas, Christa E. Müller, Anna Junker   +23 more
wiley   +2 more sources

Bioorganometallic Technetium and Rhenium Chemistry: Fundamentals for Applications

CHIMIA, 2020
Due to its long half-life of 2.111×105 y, technetium, i.e. 99Tc, offers the excellent opportunity of combining fundamental and ' classical ' organometallic or coordination chemistry with all methodologies of radiochemistry.
Roger Alberto, Henrik Braband, Qaisar Nadeem   +2 more
doaj   +1 more source

Automated GMP Production and Preclinical Evaluation of [⁶⁸Ga]Ga-TEoS-DAZA and [⁶⁸Ga]Ga-TMoS-DAZA

Pharmaceutics, 2022
[68Ga]Ga-TEoS-DAZA and [68Ga]Ga-TMoS-DAZA are two novel radiotracers suitable for functional PET liver imaging. Due to their specific liver uptake and biliary excretion, the tracers may be applied for segmental liver function quantification, gall tree ...
Julia Greiser, Thomas Winkens, Olga Perkas, Christian Kuehnel, Wolfgang Weigand, Martin Freesmeyer   +5 more
doaj   +1 more source

Carbidopa Capsules for Insulinoma Diagnostic: Compounding and Stability Study

Pharmaceutical Technology in Hospital Pharmacy, 2020
Carbidopa is a drug mainly used to treat Parkinson’s disease. Associations with levodopa or with levodopa/entacapone are commercialized, but there is no oral formulation of carbidopa alone available in Europe.
Curti Christophe, Mathias Fanny, Savelli Morane, Garrigue Philippe, Lamy Edouard, Guillet Benjamin, Vanelle Patrice   +6 more
doaj   +1 more source

Targeted Radiotherapeutics from 'Bench-to-Bedside'

CHIMIA, 2020
he concept of targeted radionuclide therapy (TRT) is the accurate and efficient delivery of radiation to disseminated cancer lesions while minimizing damage to healthy tissue and organs.
Cristina Müller, Martin Béhé, Susanne Geistlich, Nicholas P. van der Meulen, Roger Schibli   +4 more
doaj   +1 more source