99mTc-labelled S-HYNIC certolizumab pegol in rheumatoid arthritis and spondyloarthritis patients : a biodistribution and dosimetry study [PDF]
, 2016 Background: Biologicals directed against tumour necrosis factor (TNF) have proven their efficacy in the treatment of spondyloarthritis and rheumatoid arthritis.
Bacher, Klaus +9 more
core +2 more sources
THE USE OF VIRTUAL REALITY FOR TRAINING PROFESSIONALS OF NUCLEAR MEDICINE [PDF]
The use of virtual reality has becoming an important tool for training purposes, with emphasis to those procedures that involve risk to professionals, as those associated with occupational exposure to ionizing radiation in nuclear medicine services ...
CARVALHO, Juliane S. +5 more
core
Regulatory Requirements for Small-Scale Preparation of Radiopharmaceuticals
Регуляторные исследования и экспертиза лекарственных средствINTRODUCTION. The concept of pharmacy preparation of radiopharmaceuticals (RPs) was first introduced in Russia with the entry into force of the Federal Law No. 61-FZ “On Circulation of Medicines” of 12 April 2010.
G. E. Kodina +8 more
doaj +1 more source
Frontiers in Neuroscience, 2019 Neurodegenerative diseases have mainly been associated with neuronal death. Recent investigations have shown that astroglia may modulate neuroinflammation in the early and late stages of the disease.
Ingrid Kreimerman +9 more
doaj +1 more source
To serve and protect: Enzyme inhibitors as radiopeptide escorts promote tumor targeting [PDF]
, 2014 Radiolabeled octreotide analogs are most successfully being applied today in clinical cancer imaging and treatment. Propagation of this paradigm to other radiopeptide families has been greatly hampered by the inherent poor metabolic stability of ...
Jong, M. (Marcel) de +3 more
core +2 more sources
Impact of clinically tested NEP/ACE inhibitors on tumor uptake of [111In-DOTA]MG11 [PDF]
, 2016 Background: We have recently shown that treatment of mice with the neutral endopeptidase (NEP) inhibitor phosphoramidon (PA) improves the bioavailability and tumor uptake of biodegradable radiopeptides.
Jong, M. (Marion) de +6 more
core +5 more sources
Molecules, 2019 Background: The GRPR-antagonist 68Ga-SB3 visualized prostate cancer lesions in animal models and in patients. Switching radiometal from 68Ga to 111In impaired tumor targeting in mice, but coinjection of the neprilysin (NEP)-inhibitor phosphoramidon (PA ...
Emmanouil Lymperis +6 more
doaj +1 more source
Relationship between primary liver hepatocellular carcinoma volumes on portal-venous phase CT imaging [PDF]
, 2016 The liver is an important organ in the body. It is located under the rib cage on the right side. The liver performs many important functions, it processes food for nutrients that the body requires and also helps in the detoxification of harmful materials.
Aisaborhale, Ehimen Edward
core +1 more source
EphA2 as a Diagnostic Imaging Target in Glioblastoma: A Positron Emission Tomography/Magnetic Resonance Imaging Study [PDF]
, 2015 Noninvasive imaging is a critical technology for diagnosis, classification, and subsequent treatment planning for patients with glioblastoma. It has been shown that the EphA2 receptor tyrosine kinase (RTK) is overexpressed in a number of tumors ...
Boyd, Andrew W. +11 more
core +2 more sources
The clinical value of [90Y-DOTA]-D-Phe1-Tyr3-octreotide (90Y-DOTATOC) in the treatment of neuroendocrine tumours: A clinical phase II study [PDF]
, 2017 Purpose: The aim of this phase II study was to evaluate the tumour response of neuroendocrine tumours to targeted irradiation with the radiolabelled somatostatin analogue 90Y-DOTATOC.
Haldemann, A. +4 more
core