Results 21 to 30 of about 9,097 (242)
Radiosensitizing Nucleosides [PDF]
JNCI Journal of the National Cancer Institute, 1996 Chemotherapeutic drugs that perturb nucleotide metabolism have the potential to produce substantial sensitization of tumor cells to radiation treatment. The process is called radiosensitization, and the agents that induce it are called radiosensitizers.
C J, McGinn, D S, Shewach, T S, Lawrence
openaire +2 more sources
mTOR Inhibitors as Radiosensitizers in Neuroendocrine Neoplasms
Frontiers in Oncology, 2021 Peptide receptor radioligand therapy (PRRT) has evolved as an important second-line treatment option in the management of inoperable and metastatic neuroendocrine neoplasms (NEN).
Samantha Exner +7 more
doaj +1 more source
Antioxidants, 2023 Cellular adaptations to hypoxia promote resistance to ionizing radiation (IR). This presents a challenge for treatment of head and neck cancer (HNC) that relies heavily on radiotherapy.
Faisal Bin Rashed +5 more
doaj +1 more source
, 2023 In the search for effective radiosensitizers for tumor cells, halogenated uracils have attracted more attention due to their large cross section for dissociation upon the attachment of low-energy electrons.
Adrian Szczyrba (17061342) +15 more
core +2 more sources
Frontiers in Oncology, 2020 Although MASTL (microtubule-associated serine/threonine kinase-like) is an attractive target for anticancer treatment, MASTL inhibitors with antitumor activity have not yet been reported.
Ah-Young Kim +11 more
doaj +1 more source
Metallic Nanoparticles: A Useful Prompt Gamma Emitter for Range Monitoring in Proton Therapy?
Radiation, 2021 In clinical practice, dose delivery in proton therapy treatment is affected by uncertainties related to the range of the beam in the patient, which requires medical physicists to introduce safety margins on the penetration depth of the beam.
Sébastien Penninckx +5 more
doaj +1 more source
Nanomaterials, 2022 Curcumin, a natural polyphenol derived from the spice turmeric (Curcuma longa), contains antioxidant, anti-inflammatory, and anti-cancer properties. However, curcumin bioavailability is inherently low due to poor water solubility and rapid metabolism ...
Angela C. Evans +10 more
doaj +1 more source
, 2021 Radiotherapy (RT) is a frequently used means in clinical tumor treatment. The outcome of RT varies, however, to a great extent, due to RT resistance or intolerable dose, which might be resolved by the development of radio-sensitizing strategies. Here, we
Zhengyuan Huangfu (11641316) +9 more
core +1 more source
Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses
Frontiers in Oncology, 2020 Moderate hyperthermia at temperatures between 40 and 44°C is a multifaceted therapeutic modality. It is a potent radiosensitizer, interacts favorably with a host of chemotherapeutic agents, and, in combination with radiotherapy, enforces immunomodulation
Niloy R. Datta +4 more
doaj +1 more source
Electronic structure and reactivity of tirapazamine as a radiosensitizer [PDF]
, 2021 PD/BD/142846/ 2018 PD/00193/2012 .Tirapazamine (TP) has been shown to enhance the cytotoxic effects of ionizing radiation in hypoxic cells, thus making it a candidate for a radiosensitizer.
Probst, Michael +7 more
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