Results 11 to 20 of about 27,469 (292)
Au-Pt Nanoparticle Formulation as a Radiosensitizer for Radiotherapy with Dual Effects
International Journal of Nanomedicine, 2021 Song Yang, 1, 2,* Gaohua Han, 1, 2,* Quan Chen, 2, 3 Lei Yu, 1, 2 Peng Wang, 1, 2 Qi Zhang, 1, 2 Jiang Dong, 1, 2 Wei Zhang, 2, 4 Junxing Huang 1, 2 1Department of Oncology, Taizhou People’s Hospital, Taizhou, Jiangsu, People’s Republic of ...
Yang S +8 more
doaj +2 more sources
Repurposing Sulfasalazine as a Radiosensitizer in Hypoxic Human Colorectal Cancer
Cancers, 2023 Simple Summary Radiotherapy is a cornerstone for the treatment of colorectal cancer. Tumor cells present in an environment lacking oxygen (hypoxia) are resistant, leading to patient relapse.
L. Kerkhove +9 more
semanticscholar +1 more source
ACS Omega, 2022 Radiotherapy is one of the most widely used clinical treatments for tumors, but it faces limitations, such as poor X-ray retention at the tumor site. The use of radiosensitizers containing high Z elements is an effective way to enhance X-ray absorption ...
Wei Zhou +5 more
semanticscholar +1 more source
Radiosensitizing Nucleosides [PDF]
JNCI Journal of the National Cancer Institute, 1996 Chemotherapeutic drugs that perturb nucleotide metabolism have the potential to produce substantial sensitization of tumor cells to radiation treatment. The process is called radiosensitization, and the agents that induce it are called radiosensitizers.
C J, McGinn, D S, Shewach, T S, Lawrence
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Supramolecular Radiosensitizer Based on Hypoxia‐Responsive Macrocycle
Advancement of science, 2022 Radiotherapy (RT) has been viewed as one of the most effective and extensively applied curatives in clinical cancer therapy. However, the radioresistance of tumor severely discounts the radiotherapy outcomes.
Xiaoxue Hou +11 more
semanticscholar +1 more source
Bioactive Materials, 2022 The local hypoxic tumor environment substantially hampers the therapeutic efficiency of radiotherapy, which typically requires the large X-ray doses for tumor treatment but induces the serious side effects.
R. Chai +6 more
semanticscholar +1 more source
Antibody Delivery into the Brain by Radiosensitizer Nanoparticles for Targeted Glioblastoma Therapy
Journal of Nanotheranostics, 2022 Background Glioblastoma is the most lethal primary brain malignancy in adults. Standard of care treatment, consisting of temozolomide (TMZ) and adjuvant radiotherapy (RT), mostly does not prevent local recurrence.
Omer Gal +8 more
semanticscholar +1 more source
Nanomaterials, 2022 Curcumin, a natural polyphenol derived from the spice turmeric (Curcuma longa), contains antioxidant, anti-inflammatory, and anti-cancer properties. However, curcumin bioavailability is inherently low due to poor water solubility and rapid metabolism ...
Angela C. Evans +10 more
doaj +1 more source
Quisinostat is a brain-penetrant radiosensitizer in glioblastoma
bioRxiv, 2022 In recent years, histone deacetylase inhibitors (HDACi) have garnered considerable interest for the treatment of adult and pediatric malignant brain tumors.
C. Lo Cascio +12 more
semanticscholar +1 more source
Nanoparticle-Based Radiosensitization [PDF]
International Journal of Molecular Sciences, 2020 Radiotherapy is a highly affordable treatment and provides many excellent outcomes [...]
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