Results 11 to 20 of about 9,097 (242)

“Abraxane‐Like” Radiosensitizer for In Situ Oral Cancer Therapy

Advanced Science
Radiotherapy plays a vital role in cancer therapy. However, the hypoxic microenvironment of tumors greatly limits the effectiveness, thus it is crucial to develop a simple, efficient, and safe radiosensitizer to reverse hypoxia and ameliorate the ...
Zijian Gong, Yixuan Fu, Yuan Gao, Fei Jiao, Qinzhi Su, Xiao Sang, Binglin Chen, Xuliang Deng, Xinyu Liu   +8 more
doaj   +2 more sources

Triggered radiosensitizer delivery using thermosensitive liposomes and hyperthermia improves efficacy of radiotherapy: An in vitro proof of concept study. [PDF]

PLoS ONE, 2018
INTRODUCTION:To increase the efficacy of chemoradiation and decrease its toxicity in normal tissue, a new concept is proposed, local radiosensitizer delivery, which combines triggered release of a radiosensitizer from thermosensitive liposomes with local
Helena C Besse, Clemens Bos, Maurice M J M Zandvliet, Kim van der Wurff-Jacobs, Chrit T W Moonen, Roel Deckers   +5 more
doaj   +3 more sources

Vemurafenib and Radiosensitization [PDF]

JAMA Dermatology, 2013
The BRAF inhibitor, vemurafenib, was recently approved for the treatment of patients with BRAFV600 metastatic melanoma. Wider use of this drug and longer follow-up periods of treatment are resulting in the emergence of a growing number of reports detailing new adverse effects.
Lise, Boussemart, Catherine, Boivin, Joël, Claveau, Yun Gan, Tao, Gorana, Tomasic, Emilie, Routier, Christine, Mateus, Eric, Deutsch, Caroline, Robert   +8 more
openaire   +2 more sources

Vitamin D as Radiosensitizer: A Review in Cell Line [PDF]

, 2020
Introduction: Vitamin D has been shown to have anti-cancer properties such as antioxidants, anti-proliferative, and cell differentiation. The property of vitamin D as an anticancer agent triggers researchers to find out whether vitamin D is useful as a ...
Heri Wibowo, Fahmi Radityamurti, Tiara Bunga Mayang Permata, Henry Kodrat, Handoko Handoko, Fauzan Herdian, Endang Nuryadi, Soehartati A Gondhowiardjo, null Fauzan Herdian, null Tiara Bunga Mayang Permata, null Henry Kodrat, null Soehartati A Gondhowiardjo, null Fahmi Radityamurti, null Handoko Handoko, null Endang Nuryadi, null Heri Wibowo   +15 more
core   +1 more source

Evaluation of efficacy of tumor-specific nanoliposomal radiosensitizer in radiotherapy

, 2023
Radiotherapy is one of the cancer treatment options in which ionizing radiation is used. While the ionizing radiation used here damages the tumor cells, it also damages the surrounding healthy cells and tissues.
Murat Tuncel, CENGİZ, MUSTAFA, Mehmet Karabuga, Rıfkı Hazıroglu, TUNCEL, MURAT, Mustafa Cengiz, Karabuga, Mehmet, Kürsat Filikci, ERDOĞAN, SUNA, Hazıroglu, Rıfkı, Haziroglu, Rifki, Suna Erdogan, Filikci, Kürsat   +12 more
core   +1 more source

Fluorescent Gold Nanoparticles in Suspension as an Efficient Theranostic Agent for Highly Radio-Resistant Cancer Cells

Journal of Nanotheranostics, 2023
Gold nanoparticles are a promising candidate for developing new strategies of therapy against cancer. Due to their high atomic number and relative biocompatibility, they are commonly investigated as radiosensitizers to locally increase the dose of ...
Sarah Vogel, Alice O’Keefe, Léa Seban, Michael Valceski, Elette Engels, Abass Khochaiche, Carolyn Hollis, Michael Lerch, Stéphanie Corde, Christophe Massard, Komla Oscar Awitor, Moeava Tehei   +11 more
doaj   +1 more source

Radiosensitization and apoptosis [PDF]

Oncogene, 1998
The toxicity of radiation to living tissues was discovered soon after the discovery of radioactivity itself and this toxicity is the basis for cancer therapy with radiation. Although this mode of therapy is often effective, its success is far from assured.
R J, Muschel, D E, Soto, W G, McKenna, E J, Bernhard   +3 more
openaire   +2 more sources

ANTP-SMACN7 fusion peptide alone induced high linear energy transfer irradiation radiosensitization in non-small cell lung cancer cell lines

Cancer Biology & Medicine, 2022
Objective: The aim of the present study was to investigate the mechanisms responsible for the radiation-sensitizing effect of antennapedia proteins, ANTP-SMACN7, on lung cancer cells treated with accelerated carbon and Fe particle irradiation.
Yi Xie, Bing Wang, Liqing Du, Yan Wang, Chang Xu, Hong Zhang, Kaixue Wen, Qiang Liu, Takanori Katsube   +8 more
doaj   +1 more source

HDAC2 Inhibitor Valproic Acid Increases Radiation Sensitivity of Drug-Resistant Melanoma Cells

Medical Sciences, 2019
Resistance to anticancer drugs limits the effectiveness of chemotherapy in cancers. Melanoma cell lines B16F10C and A375C (parental) and B16F10R and A375R (drug-resistant sublines) were used to test radiation sensitization potential of valproic acid (VPA)
Bhuvanesh Sukhlal Kalal, Vinitha Ramanath Pai, Santosh Kumar Behera, Hiriyur Mallaiah Somashekarappa   +3 more
doaj   +1 more source

Valproic Acid-Mediated Reduction of DNA Double-Strand Break Reparation Capacity of Irradiated MCF-7 Cells [PDF]

Iranian Journal of Medical Physics, 2016
Introduction H istone deacetylase inhibitors (HDIs), as  radiation sensitizing agents, are considered as a novel class of anti-cancer factors, which are studied in various tumor cell-lines.
Ahmad yarmohamadi, Jahanbakhsh Asadi, Alireza Khoshbin khoshnazar, Mohammad Mostakhdem Hashemi   +3 more
doaj   +1 more source