Radiosensitizers - Open Access .click

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Chromosomes, Cancer, and Radiosensitivity

American Journal of Clinical Oncology, 1982
Some specific chromosomal abnormalities are associated with certain cancers. The earliest description of such a specific association is the one of the Philadelphia chromosome and myelogenous leukemia (1960). Other congenital karyotype abnormalities are associated with specific cancers. Examples of these are Down's syndrome with leukemia and Klinefelter'
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[Radiosensitizer: hypoxic cell radiosensitizer].

Gan to kagaku ryoho. Cancer & chemotherapy, 1989
There is a world-wide demand for a clinically usable sensitizer for radio-resistant hypoxic cells. After unsuccessful clinical trials of misonidazole, many efforts have been made to develop new sensitizers. In the U.S., Brown and others reported a new drug named SR-2508 (ethanidazole), which is now in phase II and III clinical trials.
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Radiosensitizers and Protectors