Results 61 to 70 of about 1,908,615 (320)

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Monte Carlo study of radiation dose enhancement by gadolinium in megavoltage and high dose rate radiotherapy. [PDF]

PLoS ONE, 2014
MRI is often used in tumor localization for radiotherapy treatment planning, with gadolinium (Gd)-containing materials often introduced as a contrast agent. Motexafin gadolinium is a novel radiosensitizer currently being studied in clinical trials.
Daniel G Zhang, Vladimir Feygelman, Eduardo G Moros, Kujtim Latifi, Geoffrey G Zhang   +4 more
doaj   +1 more source

Development of a GPU-based Monte Carlo dose calculation code for coupled electron-photon transport

, 2010
Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy.
Amitava Majumdar, Bielajew A F Hirayama H Nelson W R Rogers D W O, Briesmeister J F, Dongju Choi, Gu X, Gu X, Jacques R Taylor R Wong J McNutt T, Josep Sempau, Lensch H Strzodka R, Li J S, Li M, Ma C M, Men C, Nelson W R Hirayama H Rogers D W O, NVIDIA, Salvat F Fernández-Varea J M Baró J Sempau J, Salvat F Fernández-Varea J M Sempau J, Sempau J, Sharp G C, Steve B Jiang, Woodcock E Murphy T Hemmings P Longworth S, Xu F, Xuejun Gu, Xun Jia, Yan G R   +24 more
core   +1 more source

Experimental assessment of out‐of‐field dose components in high energy electron beams used in external beam radiotherapy

Journal of Applied Clinical Medical Physics, 2015
The purpose of this work was to experimentally investigate the out‐of‐field dose in a water phantom, with several high energy electron beams used in external beam radiotherapy (RT).
M. M. Alabdoaburas, J. Mège, J. Chavaudra, J. Bezin, A. Veres, F. de Vathaire, D. Lefkopoulos, I. Diallo   +7 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

MedLinac2: a GEANT4 based software package for radiotherapy

Annali dell'Istituto Superiore di Sanità, 2010
Dose distribution evaluation in oncological radiotherapy treatments is an outstanding problem that requires sophisticated computing technologies to optimize the clinical results (i.e.
Barbara Caccia, Claudio Andenna, Giuseppe Antonio Pablo Cirrone   +2 more
doaj   +1 more source

Monte Carlo calculation of shielding properties of newly developed heavy concretes for megavoltage photon beam spectra used in radiation therapy [PDF]

Iranian Journal of Medical Physics, 2016
Introduction: Globally, the need for radiotherapy as a part of cancer management increases every year. Thus, the shielding for megavoltage radiotherapy rooms is of great importance. Materials and Methods: In the present study, 14 types of developed high-
Rezvan Khaldari, Asghar Mesbahi, Umit Kara   +2 more
doaj   +1 more source

Feasibility study of CdZnTe and CdZnTeSe based high energy X-ray detector using linear accelerator

Nuclear Engineering and Technology, 2023
CdZnTeSe (CZTS) has attracted attention for applications in X- and gamma-ray detectors owing to its improved properties compared to those of CdZnTe (CZT).
Beomjun Park, Juyoung Ko, Jangwon Byun, Byungdo Park, Man-Jong Lee, Jeongho Kim   +5 more
doaj   +1 more source

The grid-dose-spreading algorithm for dose distribution calculation in heavy charged particle radiotherapy [PDF]

, 2007
A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed.
Ahnesjö, Azusa Ishizaki, Bortfeld, Deasy, Endo, Hollmark, Hong, Kanai, Kanematsu, Kanematsu, Kanematsu, Kanematsu, Kanematsu, Kohno, Krämer, Langen, Lomax, Mackie, Mackie, Nobuyuki Kanematsu, Noda, Petti, Russell, Schaffner, Sharpe, Shunsuke Yonai, Soukup, Szymanowski, Tsuji, Yan   +29 more
core   +3 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source