Results 51 to 60 of about 530,232 (219)

Correction to: From IB2 to IIIB locally advanced cervical cancers: report of a ten-year experience

Radiation Oncology, 2018
In the original publication [1] one author name was spelled incorrect.
Sophie Espenel, Max-Adrien Garcia, Jane-Chloé Trone, Elodie Guillaume, Annabelle Harris, Amel Rehailia-Blanchard, Ming Yuan He, Sarra Ouni, Alexis Vallard, Chloé Rancoule, Majed Ben Mrad, Céline Chauleur, Guy De Laroche, Jean-Baptiste Guy, Pablo Moreno-Acosta, Nicolas Magné   +15 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Comparison of the safety and efficacy of moderately hypofractionated and conventionally fractionated radiotherapy for localized prostate cancer: evidence from 9074 men in 13 randomized clinical trials

BMC Cancer
Objectives While moderately hypofractionated radiotherapy (HFRT) has been recommended as the standard regimen in localized prostate cancer (LPCa) based on non-inferiority trials compared to conventionally fractionated radiotherapy(CFRT), the conclusions ...
Huizhu Chen, Jiayan Chen, Feng Lyu, Mingwei Ma, Xin Qi, Xueying Ren, Shangbin Qin, Xiaomei Li, Xiaoying Li, Xiaobin Gu, Xueying Li, Hongzhen Li, Xianshu Gao   +12 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Radiotherapy in Cervical Myeloid Sarcoma: A Case Report and Literature Discussion

International Journal of Women's Health
Zi-Hong Li,* Jia-Xing Guo,* Ji-Hong Zhang, Zhi-Ling An, Xiao Liang, Li-Hua Wang, Ying-Na Bao Department of Radiotherapy, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, People’s Republic of China&ast ...
Li ZH, Guo JX, Zhang JH, An ZL, Liang X, Wang LH, Bao YN   +6 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The Prognostic Value of Combined Systemic Immune-Inflammatory Index (SII) and Prognostic Nutritional Index (PNI) in Solid Tumor

Cancer Management and Research
Yan Zhang, Min Tang, Qian-Hui Gu, Li-Na Zhou, Min-Bin Chen Department of Oncology & Radiotherapy, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, 215300, People’s Republic of ChinaCorrespondence: Min-Bin Chen, Department of ...
Zhang Y, Tang M, Gu QH, Zhou LN, Chen MB
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Prognostic Determinants of Disease-Free Survival After Curative Resection for Hepatocellular Carcinoma: A Retrospective Cohort Study

Cancer Management and Research
Nghia Trung Bui, Thau Manh Cao, Anh Gia Pham, Son Hong Trinh, Trang Thi Huyen Vo, Hang Thi Thu Nguyen, Tung Thanh Pham, Lam Thanh Phan, Hang Thu Nong, Ngoc Thi Tran, Cong Tien BuiDepartment of Oncology and Radiotherapy, Viet Duc University Hospital ...
Bui NT, Cao TM, Pham AG, Trinh SH, Vo TTH, Nguyen HTT, Pham TT, Phan LT, Nong HT, Tran NT, Bui CT   +10 more
doaj