Results 91 to 100 of about 531,735 (303)

Conventional Versus Different Hypofractionated Radiotherapy Dosage Schedules in Postmastectomy Advanced Breast Cancer. [PDF]

J Med Phys, 2022
Jain N, Sharma R, Sachdeva K, Kaur A, Sudan M.   +4 more
europepmc   +1 more source

Test of association between variant TG?1 alleles and late adverse effects of breast radiotherapy

, 2010
Purpose: to test for association between single nucleotide polymorphisms at the TGF?1 locus and the risk of late normal tissue injury following whole breast radiotherapy.Methods: a retrospective study compared the number of variant alleles at ?509 and ...
Haviland, J.S., Martin, S., Sydenham, M., A'Hern, R., Yarnold, J., Owen, R., Bliss, J., Judith Bliss, Mark Sydenham, Joanne Haviland, Roger Owen, Susan Martin, Roger A’Hern, John Yarnold   +13 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Evaluation of Calculation Errors of Treatment Planning System in Dose Distribution of Electron Beams inside the Lung in Three-Dimensional Conformal Radiation Therapy (3D-CRT)

مجله دانشکده پزشکی اصفهان, 2017
Background: Calculation of dose distribution of electron beams within in homogeneities may be complex for some of treatment planning systems (TPS). The aim of this study was to investigate the calculation errors of targeted image-guided radiation therapy
Mohammad Bagher Tavakoli, Hossein Taheri, Ali Akhavan   +2 more
doaj  

Use of radiobiological modeling in treatment plan evaluation and optimization of prostate cancer radiotherapy [PDF]

, 2011
There are many tools available that are used to evaluate a radiotherapy treatment plan, such as isodose distribution charts, dose volume histograms (DVH), maximum, minimum and mean doses of the dose distributions as well as DVH point dose constraints ...
Baltas, Dimos, Bengt K., Nikos Papanikolaou, Lind, Bengt K., Mavroidis, Panayiotis, Papanikolaou, Nikos, Bengt K. Lind, Panayiotis Mavroidis, Dimos Baltas   +8 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Ionometric methods of calibration of iridium (192Ir) brachztherapy high activity radiation sources [PDF]

Vojnosanitetski Pregled, 2003
Milošević Nebojša T., Stanković Jovan B., Dabić-Stanković Kata M.   +2 more
doaj   +1 more source

Predicting Factors of Radiosensitivity in Individual Radiotherapy

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: Radiation dose in oncology protocols is different for each patient according to the type and grade of the tumor, as well as adjuvant therapies.
Sh ghasemi, A Shabestani Monfared, S Borzoueisileh, E Zabihi, M Amiri, S Abedian   +5 more
doaj  

Radiotherapy for vestibular schwannoma: Review of recent literature results

, 2016
Background The management of vestibular schwannoma is still a quite controversial issue and can include wait and see policy, surgery and radiotherapy, mainly with stereotactic technique.
DEANTONIO, LETIZIA, Paolini, M, Apicella, G, Masini, L, KRENGLI, Marco, Masini, Laura; Radiotherapy Division, University Hospital “Maggiore della Carità”, Novara, Italy, Apicella, Giuseppina; Radiotherapy Division, University Hospital “Maggiore della Carità”, Novara, Italy, Paolini, Marina; Radiotherapy Division, University Hospital “Maggiore della Carità”, Novara, Italy, Deantonio, Letizia; Radiotherapy Division, University Hospital “Maggiore della Carità”, Novara, Italy; Department of Translational Medicine, University of “Piemonte Orientale”, Novara, Italy, Krengli, Marco; Radiotherapy Division, University Hospital “Maggiore della Carità”, Novara, Italy; Department of Translational Medicine, University of “Piemonte Orientale”, Novara, Italy; Centro Nazionale Adroterapia Oncologica (CNAO), Pavia, Italy   +9 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source