Results 91 to 100 of about 51,909 (303)

Effect of radiotherapy on the radiopacity and flexural strength of a composite resin. [PDF]

, 2008
The aim of this study was to evaluate the effect of radiotherapy on the radiopacity and flexural strength of composite resin. Forty Z250 composite resin specimens were polymerized using a halogen light-curing unit and divided into 5 groups, in accordance
Coclete, Gilberto Aparecido [UNESP], Salzedas, Leda Maria Pescinini [UNESP], Padilha, Ana C S, Santos, Paulo Henrique dos [UNESP], Catelan, Anderson   +4 more
core   +4 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Leukemia risk following radiotherapy for breast cancer. [PDF]

, 1989
To evaluate further the relationship between high-dose radiotherapy and leukemia incidence, a nested case-control study was conducted in a cohort of 22,753 women who were 18-month survivors of invasive breast cancer diagnosed from 1935 to 1972.
R E Curtis, J T Flannery, W C Moloney, M Stovall, J D Boice   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Evaluation of Calculation Errors of Treatment Planning System in Dose Distribution of Electron Beams inside the Lung in Three-Dimensional Conformal Radiation Therapy (3D-CRT)

مجله دانشکده پزشکی اصفهان, 2017
Background: Calculation of dose distribution of electron beams within in homogeneities may be complex for some of treatment planning systems (TPS). The aim of this study was to investigate the calculation errors of targeted image-guided radiation therapy
Mohammad Bagher Tavakoli, Hossein Taheri, Ali Akhavan   +2 more
doaj  

Conventional Versus Different Hypofractionated Radiotherapy Dosage Schedules in Postmastectomy Advanced Breast Cancer. [PDF]

J Med Phys, 2022
Jain N, Sharma R, Sachdeva K, Kaur A, Sudan M.   +4 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Verification of dose calculations in radiotherapy [Elektronisk resurs] [PDF]

, 2008
External radiotherapy is a common treatment technique for cancer. It has been shown that radiation therapy is a both clinically and economically effective treatment for many types of cancer, even though the equipment is expensive.
Nyholm, Tufve,, Karlsson, Mikael,, Mijnheer, Ben,   +2 more
core  

Predicting Factors of Radiosensitivity in Individual Radiotherapy

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: Radiation dose in oncology protocols is different for each patient according to the type and grade of the tumor, as well as adjuvant therapies.
Sh ghasemi, A Shabestani Monfared, S Borzoueisileh, E Zabihi, M Amiri, S Abedian   +5 more
doaj  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source