Results 121 to 130 of about 4,548,445 (364)

ADAPTATION OF LINEAR-QUADRATIC MODEL FOR PLANNING NEUTRON THERAPY REGIMENS

Сибирский онкологический журнал, 2016
Based on the fact that the parameters of the linear-quadratic model for neutron therapy were found, the comparison of single therapeutic doses in neutron therapy, calculated using the TDF (time-dose-fractionation) and linear-quadratic (LQ) models were ...
V. A. Lisin, V. V. Velikaya, I. A. Miloichikova   +2 more
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Head-to-Head Comparison of [68 Ga]Ga-FAPI-46-PET/CT and [18F]F-FDG-PET/CT for Radiotherapy Planning in Head and Neck Cancer [PDF]

, 2022
Simone Wegen, Lutz van Heek, Philipp Linde, Karina Claus, Dennis Akuamoa-Boateng, Christian Baues, Shachi Jenny Sharma, Klaus Schomäcker, Thomas Fischer, Katrin Sabine Roth, Jens Peter Klußmann, Simone Marnitz, Alexander Drzezga, Carsten Kobe   +13 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Clinical treatment planning for kilovoltage radiotherapy using EGSnrc and Python [PDF]

, 2022
Mihails Nikandrovs, Brendan McClean, Laura Shields, Patrick McCavana, Luis León Vintró   +4 more
openalex   +1 more source

The prognostic value of FET PET at radiotherapy planning in newly diagnosed glioblastoma

European Journal of Nuclear Medicine and Molecular Imaging, 2016
BackgroundGlioblastoma patients show a great variability in progression free survival (PFS) and overall survival (OS). To gain additional pretherapeutic information, we explored the potential of O-(2-18F-fluoroethyl)-L-tyrosine (FET) PET as an ...
S. H. Poulsen, T. Urup, K. Grunnet, I. Christensen, V. Larsen, M. L. Jensen, P. M. af Rosenschöld, H. Poulsen, I. Law   +8 more
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Corrigendum: Comparison of 3DCRT and IMRT out-of-field doses in pediatric patients using Monte Carlo simulations with treatment planning system calculations and measurements

Frontiers in Oncology, 2023
Ana Cravo Sá, Ana Cravo Sá, Ana Cravo Sá, Andreia Barateiro, Bryan P. Bednarz, Pedro Almeida, Pedro Vaz, Tiago Madaleno   +7 more
doaj   +1 more source

Synthesizing Efficiency Tools in Radiotherapy to Increase Patient Flow: A Comprehensive Literature Review

Clinical Medicine Insights: Oncology
The promise of novel technologies to increase access to radiotherapy in low- and middle-income countries (LMICs) is crucial, given that the cost of equipping new radiotherapy centres or upgrading existing machinery remains a major obstacle to expanding ...
Duvern Ramiah, Daniel Mmereki
doaj   +1 more source