Results 51 to 60 of about 2,696,728 (250)

A Combined Loss-driven Framework for Automated Parotid Segmentation in Head-and-Neck Computed Tomography

Journal of Medical Physics
Purpose: This study presents a deep learning framework for automatic parotid segmentation using three-dimensional (3D) U-Net and attention-augmented 3D U-Net architectures trained with a novel combined loss function tailored for anatomical accuracy and ...
Aryan Tyagi, Anuj Kumar, Sandeep Singh, Mohini Manav, Soniya Pal   +4 more
doaj   +1 more source

Criteria for Verification and Replanning Based on the Adaptive Radiotherapy Protocol “Best for Adaptive Radiotherapy” in Head and Neck Cancer

Life, 2022
No clear criteria have yet been established to guide decision-making for patient selection and the optimal timing of adaptive radiotherapy (ART) based on image-guided radiotherapy (IGRT).
Bartosz Bak, Agnieszka Skrobala, Anna Adamska, Joanna Kazmierska, Natalia Jozefacka, Tomasz Piotrowski, Julian Malicki   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Quality assurance in stereotactic radiosurgery/radiotherapy according to DIN 6875-1 [PDF]

, 2004
The new DIN (' Deutsche Industrie- Norm') 6875- 1, which is currently being finalised, deals with quality assurance ( QA) criteria and tests methods for linear accelerator and Gamma Knife stereotactic radiosurgery/ radiotherapy including treatment ...
Wolff, R., Mack, A., Rieker, M., Mack, G., Scheib, S., Czempiel, H., Gianolini, S., Wowra, B., Weltz, D., Seifert, V., Lomax, N. J., Kreiner, H. J., Muacevic, A., Böttcher, H. D.   +13 more
core   +1 more source

Deep-Learning-Based 3D Dose Distribution Prediction for VMAT Lung Cancer Treatment Using an Enhanced UNet3D Architecture with Composite Loss Functions

Bioengineering
The high complexity of radiation therapy for lung cancer necessitates effective planning of advanced treatments such as Volumetric Modulated Arc Therapy (VMAT) by radiation oncologists.
Philip Chung Yin Mak, Luoyi Kong, Lawrence Wing Chi Chan   +2 more
doaj   +1 more source

PLANNING NATIONAL RADIOTHERAPY SERVICES

Frontiers in Oncology, 2014
Countries, states and island nations often need forward planning of their radiotherapy services driven by different motives. Countries without radiotherapy services sponsor patients to receive radiotherapy abroad.
Eduardo eRosenblatt
doaj   +1 more source

Synthetic MRI for Radiotherapy Planning for Brain and Prostate Cancers: Phantom Validation and Patient Evaluation

Frontiers in Oncology, 2022
PurposeWe aimed to evaluate the accuracy of T1 and T2 mappings derived from a multispectral pulse sequence (magnetic resonance image compilation, MAGiC®) on 1.5-T MRI and with conventional sequences [gradient echo with variable flip angle (GRE-VFA) and ...
Pierrick Gouel, Pierrick Gouel, Sebastien Hapdey, Sebastien Hapdey, Arthur Dumouchel, Isabelle Gardin, Isabelle Gardin, Isabelle Gardin, Eva Torfeh, Pauline Hinault, Pierre Vera, Pierre Vera, Sebastien Thureau, Sebastien Thureau, Sebastien Thureau, David Gensanne, David Gensanne, David Gensanne   +17 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Dosimetric Evaluation of Advanced Radiotherapy Techniques in Treating Patients with Prostatic Cancer [PDF]

Research in Oncology, 2017
Background: Different radiotherapy techniques were developed to deliver optimal dose to prostate cancer while sparing nearby organs at risk (OARs).Aim: To compare different dosimetric methods used to evaluate sparing of OARs and to select radiotherapy ...
Amin Amin, Somaia El Sayed, Ahmed Ezzat
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source