Results 91 to 100 of about 4,569 (190)

Exploring the Burden on Patients Living With and Receiving Treatment for Immune Thrombocytopenia (ITP): Patient and Physician Perceptions From the ITP World Impact Survey (I‐WISh) 2.0

American Journal of Hematology, Volume 101, Issue 8, Page 1954-1968, August 2026.
ABSTRACT Limited data exist on how patients and physicians perceive immune thrombocytopenia (ITP) symptoms and treatment‐related burden. I‐WISh (ITP World Impact Survey) 2.0 surveyed 1018 patients and 431 physicians in 15 countries to characterize the impact of ITP and its treatments on patients.
Nichola Cooper, James Bussel, Waleed Ghanima, Drew Provan, Yoshiaki Tomiyama, Ming Hou, Donald M. Arnold, Cristina Santoro, Francesco Zaja, Barbara Lovrencic, Mervyn Morgan, Michal Winograd, Jennifer DiRaimo, Danielle Boyle, Olivera Rajkovic‐Hooley, Meritxell Vendranas, Susan Frade, Caroline Kruse   +17 more
wiley   +1 more source

Temporal order of clinical, imaging, and biomarker changes in frontotemporal lobar degeneration–associated syndromes

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract BACKGROUND The temporal sequence of clinical, imaging, and biological changes in sporadic frontotemporal lobar degeneration (FTLD)–associated syndromes remains poorly characterized, and a comprehensive biomarker cascade model is lacking. METHODS We developed a data‐driven biomarker cascade model in 489 patients across the FTLD spectrum (211 ...
Alberto Benussi, Valeria Bracca, Enrico Premi, Valentina Cantoni, Federica Palacino, Aurora Saccavini, Maria Sofia Cotelli, Giuliano Binetti, Rosa Manenti, Antonella Alberici, Roberto Gasparotti, Nicholas J Ashton, Henrik Zetterberg, Kaj Blennow, Roberta Ghidoni, Barbara Borroni   +15 more
wiley   +1 more source

Review on Recent Advances in Conducting Polymer/Metal‐Oxide Nanocomposite Chemiresistors for Environmental Gas Monitoring

Macromolecular Materials and Engineering, Volume 311, Issue 8, August 2026.
Conducting polymer/metal‐oxide nanocomposites emerge as highly promising chemiresistive sensing materials for environmental gas monitoring. Recent advances reveal strong synergistic effects that enhance sensitivity, selectivity, stability, and response kinetics while enabling lower‐temperature operation.
Katekani Shingange, Sivuyisiwe Mapukata, Teboho Mokhena, Thandi Patricia Gumede, David Rogers, Martin Ntwaeaborwa   +5 more
wiley   +1 more source

Research Progress in the Preparation Technology of Radium-223

Journal of Isotopes
223Ra is a low toxicity substance α Radiotherapy nuclide, which can be used to treat castrated resistant prostate cancer (CRPC) with symptoms of bone metastasis and no visceral metastasis, was the first approved alpha therapy radiopharmaceutical on the ...
Junshan GENG, Jianrong WU, Qian XIAO, Bo LI, Yunming CHEN, Jingsong ZHANG, Ning LUO   +6 more
doaj   +1 more source

Lymphatic Endothelial Cells in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang, Wang Lin, Hengyang Liu, Jixin Zhong, Shiliang Li, Xiaoquan Rao   +5 more
wiley   +1 more source

Cardiovascular Diseases and Cancer: Convergent Proteostasis Networks at the Crossroads of Mechanisms and Therapeutic Opportunities

MedComm, Volume 7, Issue 8, August 2026.
The disruption of proteostasis, encompassing the ubiquitin–proteasome system, autophagy, UPR/ER stress, and chaperone function, represents a fundamental mechanism shared by both cancer and cardiovascular diseases. While these pathways frequently facilitate tumor progression, they are crucial for maintaining proteostasis in cardiac tissue. Consequently,
Jacob Eli García Torres, Norbert Frey, Ashraf Yusuf Rangrez   +2 more
wiley   +1 more source

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source

Fatal Pancytopenia Associated with Radium-223 Dichloride in a Patient with Castration-Resistant Prostate Cancer and Multiple Bone Metastases

Case Reports in Clinical Practice, 2018
Radium-223 dichloride (Ra-223) is an alpha-emitting radioisotope that targets osteoblastic metastasis of prostate cancer. For Ra-223, a favorable safety profile has been described.
Yukihiro Hama, shoji koga
doaj  

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

Metal Halide Perovskite Quantum Dots for Luminescence Sensing and Imaging

Nano Select, Volume 7, Issue 8, August 2026.
This review highlights recent advances in metal halide perovskite quantum dots (PQDs)‐based photoluminescence, chemiluminescence, and electroluminescence sensing methods, as well as bioimaging applications. Key challenges, potential solutions, and future opportunities are discussed to guide the development of robust PQD‐based sensing platforms ...
Tooba Hallaj, Rana Salari, Seyyed Morteza Seyyed Alavi, Muhammad Munir, Niko Hildebrandt, Mohammad Amjadi   +5 more
wiley   +1 more source