Results 41 to 50 of about 9,194 (267)

Development of a method for control of radiopharmaceuticals [PDF]

open access: yes, 2021
The aim of the study is to draw up a method for monitoring the isotopic composition of medical solutions of radium-223. The possibility of using gamma spectrometry for control of radium-223, its decay products, and its parent isotopes are considered in ...
Безденежных, Илья Викторович   +13 more
core   +2 more sources

A phase II randomized trial of RAdium-223 dichloride and SABR Versus SABR for oligomEtastatic prostate caNcerS (RAVENS)

open access: yesBMC Cancer, 2020
Background Metastasis directed therapy (MDT) for patients with oligometastatic disease is associated with improvements in progression free survival (PFS) and overall survival (OS) compared to systemic therapy alone. Additionally, within a prostate-cancer-
Hamza Hasan   +30 more
doaj   +1 more source

Radium-223 in combination with enzalutamide in metastatic castration-resistant prostate cancer: a multi-centre, phase II open-label study

open access: yesTherapeutic Advances in Medical Oncology, 2021
Background: Radium-223 and enzalutamide are approved agents for patients with metastatic castration-resistant prostate cancer (mCRPC). Combining radium-223 and enzalutamide to improve outcomes is of clinical interest due to their differing modes of ...
Raymond S. McDermott   +13 more
doaj   +1 more source

Quantifying the survival benefit of completing all the six cycles of radium-223 therapy in patients with castrate-resistant prostate cancer with predominant bone metastases

open access: yesWorld Journal of Nuclear Medicine, 2021
A retrospective analysis was performed of epidemiological data assessing the survival of patients who had received radium-223 for castrate-resistant metastatic prostate cancer treated at a regional tertiary referral center over a 5-year period.
John Buscombe   +5 more
doaj   +1 more source

Persistent neutrophil to lymphocyte ratio >3 during treatment with enzalutamide and clinical outcome in patients with castration-resistant prostate cancer [PDF]

open access: yes, 2016
The baseline value of neutrophil to lymphocyte ratio (NLR) has been found to be prognostic in patients with metastatic castration resistant prostate cancer (CRPC). We evaluated the impact of baseline NLR and its change in patients receiving enzalutamide.
Caffo, Orazio   +15 more
core   +3 more sources

Navigating the mCRPC Landscape: Exploring Key Clinical Decision Points [PDF]

open access: yesEuropean Medical Journal Urology, 2015
The Bayer satellite symposium was introduced by Prof Fred Saad, who gave an introduction into the use of radium-223 in metastatic castration-resistant prostate cancer (mCRPC).
Fred Saad   +3 more
doaj  

Factors Influencing Outcome Post–Radium-223 Dichloride in Castrate Resistant Prostate Cancer: A Review of Some Real-World Challenges

open access: yesWorld Journal of Nuclear Medicine, 2022
Aim Radium-223 has been the first-approved targeted Alpha therapy agent. We retrospectively assessed different factors influencing the overall survival (OS) and patient management.
Amit Bhoil   +3 more
doaj   +1 more source

Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment [PDF]

open access: yes, 2020
BACKGROUND: Docetaxel chemotherapy in prostate cancer has a modest impact on survival. To date, efforts to develop combination therapies have not translated into new treatments. We sought to develop a novel therapeutic strategy to tackle chemoresistant
Dufès, Christine   +9 more
core   +3 more sources

Cost-effectiveness Analysis of Radium-223 Dichloride in Metastatic Castration-Resistant Prostate Cancer Patients Without Previous Chemotherapy Treatment in Spain

open access: yesJournal of Health Economics and Outcomes Research, 2018
# Purpose To perform a cost-effectiveness analysis of radium-223 plus Best Supportive Care (BSC) compared to BSC in the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) and without previous docetaxel treatment in Spain.
Eva Tirado Mercier   +4 more
doaj   +1 more source

First Report of NRG Oncology/Radiation Therapy Oncology Group 0622: A Phase 2 Trial of Samarium-153 Followed by Salvage Prostatic Fossa Irradiation in High-Risk Clinically Nonmetastatic Prostate Cancer After Radical Prostatectomy. [PDF]

open access: yes, 2018
PURPOSE: To investigate the utility of 153Sm lexidronam (Quadramet) in the setting of men with prostate cancer status post radical prostatectomy who develop biochemical failure with no clinical evidence of osseous metastases.
Girvigian, Michael R.   +10 more
core   +2 more sources

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