Results 1 to 10 of about 230,634 (272)

Bessel-beam illumination Raman microscopy. [PDF]

open access: yesBiomed Opt Express, 2022
We demonstrate the use of Bessel beams for side illumination slit-scanning Raman imaging for label-free and hyperspectral analysis of cell spheroids. The background elimination by the side illumination and the aberration-resistant Bessel beam drastically improves the image contrast in Raman observation, allowing label-free investigation of ...
Bando K   +6 more
europepmc   +3 more sources

Compound Raman microscopy for rapid diagnosis and antimicrobial susceptibility testing of pathogenic bacteria in urine [PDF]

open access: yesFrontiers in Microbiology, 2022
Rapid identification and antimicrobial susceptibility testing (AST) of bacteria are key interventions to curb the spread and emergence of antimicrobial resistance.
Weifeng Zhang   +9 more
doaj   +2 more sources

Correlative Fluorescence and Raman Microscopy to Define Mitotic Stages at the Single-Cell Level: Opportunities and Limitations in the AI Era [PDF]

open access: yesBiosensors, 2023
Nowadays, morphology and molecular analyses at the single-cell level have a fundamental role in understanding biology better. These methods are utilized for cell phenotyping and in-depth studies of cellular processes, such as mitosis.
Csaba Voros   +11 more
doaj   +2 more sources

Novel exploration of Raman microscopy and non-linear optical imaging in adenomyosis [PDF]

open access: yesFrontiers in Medicine, 2022
BackgroundAdenomyosis is a common gynecological disease in women. A relevant literature search found that approximately 82% of patients with adenomyosis chose to undergo hysterectomy.
Zhuowei Shen   +9 more
doaj   +2 more sources

Non-Uniform Distribution of Cryoprotecting Agents in Rice Culture Cells Measured by CARS Microscopy

open access: yesPlants, 2021
Cryoprotectants allow cells to be frozen in liquid nitrogen and cryopreserved for years by minimizing the damage that occurs in cooling and warming processes.
Fionna M. D. Samuels   +4 more
doaj   +1 more source

Assessment of Prediction Models for Punch Sticking in Tablet Formulations

open access: yesBritish Journal of Pharmacy, 2022
Punch sticking is a common tablet compression manufacturing issue experienced during late-stage large-scale manufacturing. Prediction of punch sticking propensity and identification of the sticking component is important for early-stage formulation ...
Edward Paul Rhodes   +5 more
doaj   +1 more source

Formation mechanisms of sub-micron pharmaceutical composite particles derived from far- and near-field Raman microscopy

open access: yesJournal of Pharmaceutical Analysis, 2021
Surface enhanced Raman spectroscopy (SERS) and confocal Raman microscopy are applied to investigate the structure and the molecular arrangement of sub-micron furosemide and polyvinylpyrrolidone (furosemide/PVP) particles produced by spray flash ...
Jakob Hübner   +3 more
doaj   +1 more source

Applicability of Confocal Raman Microscopy to Observe Microstructural Modifications of Cream Cheeses as Influenced by Freezing

open access: yesFoods, 2020
Confocal Raman microscopy is a promising technique to derive information about microstructure, with minimal sample disruption. Raman emission bands are highly specific to molecular structure and with Raman spectroscopy it is thus possible to observe ...
Marcello Alinovi   +6 more
doaj   +1 more source

Coherent Stokes Raman scattering microscopy (CSRS)

open access: yesNature Communications, 2023
We report the first implementation of laser scanning coherent Stokes Raman scattering (CSRS) microscopy. To overcome the major challenge in CSRS imaging, we show how to suppress the fluorescence background by narrow bandpass filter and a lock-in based ...
Sandro Heuke, Hervé Rigneault
doaj   +1 more source

Raman Microscopy: Complement or Competitor? [PDF]

open access: yes, 2010
The objective of this chapter is to provide an introduction to Raman spectroscopic microscopy and its potential for biochemical analysis and clinical diagnostic applications, such that it can be compared and contrasted to the techniques of synchrotron and bench-top mid-FTIR spectroscopy discussed el...
Byrne, Hugh   +2 more
openaire   +2 more sources

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