Results 81 to 90 of about 15,894 (297)
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Ramification and unintegrated value distribution [PDF]
Let f be a holomorphic map from \({\mathbb{C}}\) into a Riemann sphere \({\mathcal S}\) of surface area 1. In contrast with the known estimates for the integrated counting function of the ramification prints of f, the paper introduces a ''proximate counting function'' and estimates the same, from above, under suitable conditions.
openaire +3 more sources
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Ramification sequences and Bezoutian forms
: We continue our study from [1] on the problem to bound the number of symbols needed to obtain an element of the second K-group of a rational function field with given ramification.
Becher, Karim Johannes +1 more
core
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
FAMILIES OF ELLIPTIC FUNCTIONS AND UNIFORMIZATION OF COMPLEX TORI WITH A UNIQUE POINT OVER INFINITY
We investigate the problem of describing a one-parametric family of elliptic functions which uniformizes a given family of ramified coverings of the Riemann sphere with maximal possible ramification over infinity.
S. R. Nasyrov
doaj +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Ramification of the dorsal clitoral nerve along its course on the human clitoris
BACKGROUND: The detailed anatomy of the human bulboclitoral organ remains, despite recent efforts of morphological disciplines, a largely unstudied area.
Michael Wolf-Vollenbröker +3 more
doaj +1 more source

