Results 81 to 90 of about 29,147 (185)

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

European journal of cell biology, 1996
A partial cDNA clone coding for the mouse homologue of the human Ran-GTP binding protein, RanBP2, has been isolated by screening of a murine expression library with antibodies to nup180, a previously identified nuclear pore complex protein (nucleoporin).
N, Wilken, J L, Senécal, U, Scheer, M C, Dabauvalle   +3 more
openaire   +1 more source

Expanding the Fish‐Brain Invitrome With the Senegalese Sole SsB‐1 Cell Line—A Versatile Model for Neurotropic Virus Research

Journal of Fish Diseases, EarlyView.
ABSTRACT Cell lines are essential tools for studying animal physiology and immunopathology, reducing the use of live animals and supporting the 3Rs principle of reduction, refinement, and replacement. The Senegalese sole (Solea senegalensis), a relevant species for Spanish aquaculture diversification, lacks established in vitro models. We developed SsB‐
Yulema Valero, Alberto Cuesta
wiley   +1 more source

Finding the middle ground: how kinetochores power chromosome congression [PDF]

, 2010
ISSN:1420-682XISSN:1420 ...
Geert J. P. L. Kops, Adrian T. Saurin, Patrick Meraldi, HWG Waldeyer, W Flemming, T Boveri, WS Sutton, TH Morgan, T Boveri, AJ Holland, Z Storchova, CD Darlington, RB Nicklas, HS Yu, B Liu, DF Kubai, AF Straight, N Paweletz, F Schrader, F Schrader, LW Sharp, A Khodjakov, BR Brinkley, CB O’Connell, CL Rieder, GJ Brouhard, C Antonio, H Funabiki, NJ Ganem, AA Levesque, A Santamaria, JG DeLuca, JG DeLuca, S Martin-Lluesma, ML McCleland, D Dujardin, MJ Emanuele, TN Gaitanos, A Hanisch, Y Mao, BF McEwen, K Momotani, P Pierre, FR Putkey, JA Raaijmakers, ME Tanenbaum, M Theis, JP Welburn, S Cai, R Heald, J Gaetz, KW Wood, CB O’Connell, CE Walczak, JH Hayden, CL Rieder, PR Clarke, H Maiato, BM Paschal, Y Li, Z Yang, VV Vorozhko, BJ Howell, CJ Echeverri, MS Savoian, DA Starr, P Bomont, YW Chan, MA Vergnolle, SA Stehman, ER Griffis, D Varma, TU Tanaka, JJ Miranda, S Westermann, DR Gestaut, K Tanaka, P Meraldi, AF Powers, EL Grishchuk, S Westermann, R Gassmann, IM Cheeseman, C Ciferri, MA Lampson, PS Maddox, P Meraldi, ES Gillett, C Klebig, CD Warren, CL Rieder, TM Kapoor, J Loncarek, RB Nicklas, D Cimini, D Cimini, C Ditchfield, S Hauf, GJ Guimaraes, PD Andrews, A Desai, AW Hunter, FA Barr, L Wordeman, AL Knowlton, L Wordeman, BB Gadea, AL Knowlton, SF Bakhoum, TU Tanaka, D Liu, G Oestergren, S Cai, J Stumpff, JB Peterson, H Maiato, HP Lin, CL Rieder, R Ding, JS Tirnauer, KJ VandenBeldt, Y Zhai, TJ Mitchison, H Maiato, JC Waters, A Toso, NJ Ganem, RV Skibbens, WH Lewis, AF Hughes, J Molé-Bajer, T Seto, A Khodjakov, AD Silk, K Ke, MI Mayr, A Akhmanova, V Varga, MK Gardner, J Espeut, P Lenart, CY Jang, J Wong, VL Johnson, MA Lampson, N Jelluma, JF Maure, S Elowe, OK Wong, A Seki, L Macurek, S Matsumura, BG Fuller, A Santamaria, K Hoar, JD Blethrow, V Vanoosthuyse, BA Pinsky, J Liu, CA Athale, P Kalab, CB O’Connell, A Arnaoutov, J Joseph, A Arnaoutov, M Delacour-Larose, SE McClelland, L Schermelleh, V Westphal, E Betzig, G Shtengel, KI Willig, I Matos, P Maddox, A Desai, S Maffini, A Akhmanova   +176 more
core   +1 more source

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

Plant, Cell &Environment, EarlyView.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source

RAB family gene expression in breast cancer cells under influence of paclitaxel [PDF]

, 2011
The aim of this study was to investigate the role of paclitaxel on RAB family of genes in primary breast cancer cell lines. The cancer breast cells obtained from 40 women during mastectomy were used to address this issue. The group included patients with
Andrzej Wilkolaski, Jolanta Rzymowska, Piotr Maj, Tadeusz Malewski   +3 more
core   +1 more source

Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. [PDF]

, 2018
Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined.
Bibikova, Elena, Danilova, Nadia, Lin, Shuo, Sakamoto, Kathleen M, Wilkes, Mark, Youn, Min-Young   +5 more
core   +2 more sources

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

PACAP induces FSHβ gene expression via EPAC. [PDF]

, 2019
Gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), are heterodimers of a common α subunit and unique β subunits. Regulation of their levels, primarily by GnRH, is critical for reproductive function.
Coss, Djurdjica, Yeh, Debra M
core  

C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. [PDF]

, 2016
Intronic hexanucleotide expansions in C9ORF72 are common in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia, but it is unknown whether loss of function, toxicity by the expanded RNA or dipeptides from non-ATG-initiated translation are ...
A Burberry, A Michalski, AE Renton, AR Haeusler, BJ Agnew, C Lagier-Tourenne, CJ Donnelly, D Hornburg, D Zhang, DJ Hernández-Deviez, E Majounie, E Sudria-Lopez, EC Keilhauer, EH Franssen, F Tronche, H Radhakrishna, I Gijselinck, J Cox, J Cox, J Cox, J Japtok, J Jiang, J Rappsilber, JG O'Rourke, JJ Bravo-Cordero, K Mori, K Moriyama, K Nunoue, KC Flynn, LA Cingolani, LC Santy, M Bourmoum, M DeJesus-Hernandez, M Fischer, M Innocenti, M Innocenti, M Koppers, M Therrien, MA Farg, ML Rogers, N Subramanian, N Wächter, N Yang, O Al-Awar, O Bernard, P Fratta, P Reinhardt, P Reinhardt, PM Sullivan, R Götz, S Ciura, S Iden, S Jablonka, S Lewis-Saravalli, S May, S Stern, S Tyanova, S Wiese, SC Ling, T Zu, TP Levine, W Huang, X Lojewski, X Wen   +63 more
core   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source