Results 91 to 100 of about 3,675,924 (300)
, 2014 Experimental investigations into the dynamic response of structures with material or geometrical random fields usually depend upon an initial characterization of this variability, with very little control over the statistics at its early manufacturing ...
Ferguson, N.S. +4 more
core +1 more source
Control of the Metastable State of a Memory Element for the Purpose of Random Data Generation
Доклады Белорусского государственного университета информатики и радиоэлектроникиA new scheme for constructing truly random sequence generators using a randomness source control unit is proposed. A generalized controlled bistable element is considered as a source of randomness, for which a lo gical model based on controlled feedback ...
M. N. Kaiky, A. A. Ivaniuk
doaj +1 more source
Computing quantities of interest for random domains with second order shape sensitivity analysis [PDF]
, 2014 We consider random perturbations of a given domain. The characteristic amplitude of these perturbations is assumed to be small. We are interested in quantities of interest which depend on the random domain through a boundary value problem.
Marc Dambrine +5 more
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Differential Equations and Nonlinear Mechanics, 2007 The stochastic finite element method (SFEM) is employed for solving stochastic one-dimension time-dependent differential equations with random coefficients. SFEM is used to have a fixed form of linear algebraic equations for polynomial chaos coefficients
M. M. Saleh, I. L. El-Kalla, M. M. Ehab
doaj +1 more source
Some procedures for extending random operators
, 2009 Let X and Y be separable Banach spaces and E be a subset of X. By a random operator from X into Y we mean a rule Φ that assigns to each element x ∈ X a unique Y - valued random variable Φx.
Thang D.H., Cuong T.M.
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Finite element based fatigue analysis of 6082 Aluminum alloy under random loading
Journal of Materials and Engineering Structures, 2018 Mechanical and structural components are subject in the most cases during their services to random loading. For this reason, it is necessary to reduce the complex history of these kinds of loading in a series of constant amplitude cycles.
Habib KHELLAFI +6 more
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