Results 101 to 110 of about 3,675,924 (300)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
工程科学与技术ObjectiveAccurate assessment of the strength characteristics and deformation behavior of geocell-reinforced retaining wall structures is crucial for their safety and stability during long-term service.
ZHANG Bingbing, SONG Fei
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Grey Wolf Optimization algorithm with random local optimal regulation and first-element dominance
Egyptian Informatics JournalDue to the classical Grey Wolf algorithm GWO does not consider the characteristics of the local information of individual in population, a novel local random optimization strategy is proposed to make up for the defect of GWO.
Xuan Yanzhuang, Xuan Shibin
doaj +1 more source
Random Differential Topology [PDF]
, 2020 The topic discussed in this thesis are at the crossroad of Differential Topology and Random Geometry. In the first chapter a general framework to deal with issues of differential geometric and topological nature regarding smooth Gaussian Random Fields
Stecconi, Michele
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Random walk in random environment with asymptotically zero perturbation [PDF]
, 2006 We give criteria for ergodicity, transience and null recurrence for the random walk in random environment on \Z+={0,1,2,…}, with reflection at the origin, where the random environment is subject to a vanishing perturbation.
Menshikov, Mikhail V., Wade, Andrew
core +2 more sources
A Discrete-Element-Based Approach to Generate Random Parameters for Soil Fatigue Models
Journal of Marine Science and EngineeringThe structural reliability of bottom-fixed offshore wind turbines is generally influenced by the dispersion of and variability in soil properties, which affect their ultimate capacity, serviceability, and both the short- and long-term fatigue.
Alessandro Tombari, Fedor Maksimov
doaj +1 more source
Deep Hankel matrices with random elements
CoRRL4DC ...
Nathan P. Lawrence +4 more
openaire +4 more sources