Results 61 to 70 of about 805,112 (303)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

RESEARCH OF THE RETRIAL QUEUEING SYSTEMS OPERATING IN SEMI-MARKOV ENVIRONMENT

open access: yesВестник Кемеровского государственного университета, 2014
The paper is devoted to the mathematical models of retrial queueing systems concerning semi-Markov environment influence on the repeated calls source and services.
V. A. Vavilov
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Random motion of a circle microswimmer in a random environment

open access: yesNew Journal of Physics, 2020
We simulate the dynamics of a single circle microswimmer exploring a disordered array of fixed obstacles. The interplay of two different types of randomness, quenched disorder and stochastic noise, is investigated to unravel their impact on the transport
Oleksandr Chepizhko, Thomas Franosch
doaj   +1 more source

Random walk with barycentric self-interaction

open access: yes, 2010
We study the asymptotic behaviour of a $d$-dimensional self-interacting random walk $X_n$ ($n = 1,2,...$) which is repelled or attracted by the centre of mass $G_n = n^{-1} \sum_{i=1}^n X_i$ of its previous trajectory. The walk's trajectory $(X_1,...,X_n)
Volkov, S.   +13 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Non-homogeneous random walks with non-integrable increments and heavy-tailed random walks on strips

open access: yes, 2012
We study asymptotic properties of spatially non-homogeneous random walks with non-integrable increments, including transience, almost-sure bounds, and existence and non existence of moments for first-passage and last-exit times.
MacPhee, Iain M.   +9 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Performance Modeling of Cloud Systems by an Infinite-Server Queue Operating in Rarely Changing Random Environment

open access: yesFuture Internet
This paper considers a heterogeneous queuing system with an unlimited number of servers, where the parameters are determined by a random environment. A distinctive feature is that the parameters of the exponential distribution of the request processing ...
Svetlana Moiseeva   +3 more
doaj   +1 more source

Random environment on coloured trees

open access: yes, 2007
International audienceIn this paper we study a regular rooted coloured tree with random labels assigned to its edges, where the distribution of the label assigned to an edge depends on the colours of its endpoints.
Petritis, Dimitri   +2 more
core   +1 more source

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