NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Field Induced Memory Effects in Random Nematics
Advances in Condensed Matter Physics, 2014 We studied numerically external field induced memory effects in randomly perturbed nematic liquid crystals. Random anisotropy nematic-type lattice model was used. The impurities imposing orientational disorder were randomly spatially distributed with the
Amid Ranjkesh +3 more
doaj +1 more source
The Tensor Track VI: Field Theory on Random Trees and SYK on Random Unicyclic Graphs [PDF]
, 2020 Nicolas Delporte, Vincent Rivasseau
openalex +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Undrained stability of braced excavations in clay considering the nonstationary random field of undrained shear strength. [PDF]
Sci Rep, 2023 Tanapalungkorn W +6 more
europepmc +1 more source
A Markov Random Field Topic Space Model for Document Retrieval [PDF]
, 2011 Scott Hand
openalex +1 more source
One-dimensional random field Kac's model: localization of the phases [PDF]
, 2004 We study the typical profiles of a one dimensional random field Kac model, for values of the temperature and magnitude of the field in the region of the two absolute minima for the free energy of the corresponding random field Curie Weiss model.
Cassandro, Marzio +3 more
core +2 more sources
Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong +7 more
wiley +1 more source
Random field calibration with data on irregular grid for regional analyses: A case study on the bare carrying capacity of bats in Africa. [PDF]
Ecol Evol, 2023 Mursel S +4 more
europepmc +1 more source
Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source