Results 91 to 100 of about 2,732,958 (292)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Critical behavior of colloid-polymer mixtures in random porous media
, 2006 We show that the critical behavior of a colloid-polymer mixture inside a random porous matrix of quenched hard spheres belongs to the universality class of the random-field Ising model.
A. van Blaaderen +9 more
core +1 more source
, 2004 Invited talk at the DAE Solid State Physics Symposium, Gwalior, India, (Dec, 2003)
openaire +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
REVIEW OF RECENT RESULTS ON EXCURSION SET MODELS
Image Analysis and Stereology, 2011 Many images consist of two or more "phases", where a phase is a collection of homogeneous zones. For example, the phases may represent the presence of different sulphides in an ore sample.
Richard J Wilson, David J Nott
doaj +1 more source
, 2012 With this Letter, we complete our model of the Galactic magnetic field (GMF), by using the WMAP7 22 GHz total synchrotron intensity map and our earlier results to obtain a 13-parameter model of the Galactic random field, and to determine the strength of ...
Farrar, Glennys R., Jansson, Ronnie
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
On adaptive refinements in discrete probabilistic fracture models
Fracture and Structural Integrity, 2016 The possibility to adaptively change discretization density is a well acknowledged and used feature of many continuum models. It is employed to save computational time and increase solution accuracy.
J. Eliáš
doaj
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Conditional random field tracking model based on a visual long short term memory network
Journal of Electronic Science and Technology, 2020 In dense pedestrian tracking, frequent object occlusions and close distances between objects cause difficulty when accurately estimating object trajectories.
Pei-Xin Liu +3 more
doaj +1 more source