Results 51 to 60 of about 172,035 (261)
Tail Index Estimation of PageRanks in Evolving Random Graphs
Mathematics, 2022 Random graphs are subject to the heterogeneities of the distributions of node indices and their dependence structures. Superstar nodes to which a large proportion of nodes attach in the evolving graphs are considered.
Natalia Markovich +2 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Diameter of the Minimum Spanning Tree of a Complete Graph [PDF]
Discrete Mathematics & Theoretical Computer Science, 2006 Let $X_1,\ldots,X_{n\choose 2}$ be independent identically distributed weights for the edges of $K_n$. If $X_i \neq X_j$ for$ i \neq j$, then there exists a unique minimum weight spanning tree $T$ of $K_n$ with these edge weights.
Louigi Addario-Berry +2 more
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The probability of planarity of a random graph near the critical point [PDF]
Discrete Mathematics & Theoretical Computer Science, 2013 Erdős and Rényi conjectured in 1960 that the limiting probability $p$ that a random graph with $n$ vertices and $M=n/2$ edges is planar exists. It has been shown that indeed p exists and is a constant strictly between 0 and 1.
Marc Noy +2 more
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Identify the Subject and Content of Tweets on Twitter Using Multilayer Neural Network Method and Random Graphs [PDF]
International Journal of Information and Communication Technology Research, 2023 The result of the research is a proposed model for text analysis and identifying the subject and content of texts on Twitter. In this model, two main phases are implemented for classification.
Vahid Yazdanian +2 more
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Random graphs, models and generators of scale-free graphs
Труды Института системного программирования РАН, 2018 In this paper various models of random graphs describing real networks arising in different research fields: biology, computer science, engineering, sociology are considered. Particular attention is paid to models describing social networks.
M. M. Bernovskiy, N. N. Kuzyurin
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