Results 91 to 100 of about 554,533 (301)

Radiation Transport in Random Media With Large Fluctuations

open access: yesEPJ Web of Conferences, 2017
Neutral particle transport in media exhibiting large and complex material property spatial variation is modeled by representing cross sections as lognormal random functions of space and generated through a nonlinear memory-less transformation of a ...
Olson Aaron, Prinja Anil, Franke Brian
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Angularly resolved reflectance from random and aligned semi-infinite media

open access: yesAtti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2011
The angularly resolved reflectance from semi-infinite turbid media is investigated using the Monte Carlo method. Turbid media with random and aligned microstructures are considered.
A. Kienle, F. Foschum
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Media Analysis (MA 2002, Press Media II)

open access: yes, 2003
The study series "Media Analyse" is an annual, systematic survey of media usage among the German population which is conducted by "Arbeitsgemeinschaft für Media-Analyse (AGMA)“.
Arbeitsgemeinschaft Media-Analyse, Frankfurt am Main   +1 more
core   +2 more sources

Media Analysis (MA 99, Press Media I)

open access: yes, 2000
The study series "Media Analyse" is an annual, systematic survey of media usage among the German population which is conducted by "Arbeitsgemeinschaft für Media-Analyse (AGMA)“.
Arbeitsgemeinschaft Media-Analyse, Frankfurt am Main   +1 more
core   +2 more sources

Lensless imaging based on coherent backscattering in random media

open access: yesAIP Advances, 2014
We studied lensless imaging due to coherent backscattering in random media both theoretically and experimentally. The point spread function of the lensless imaging system was derived.
Lei Xu   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Fluids in Random Media and Dimensional Augmentation

open access: yesPhysical Review Letters, 2023
We propose a solution to the puzzle of dimensional reduction in the random field Ising model, inverting the question and asking: to what random problem in $D=d+2$ dimensions does a pure system in $d$ dimensions correspond? We consider two models: a continuum binary fluid, and a lattice gas which maps exactly onto an Ising model.
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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