Results 31 to 40 of about 20,745 (303)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Accuracy in random number generation [PDF]

open access: yesMathematics of Computation, 1985
The generation of continuous random variables on a digital computer encounters a problem of accuracy caused by approximations and discretization error. These in turn impose a bias on the simulation results. An ideal discrete approximation of a continuous distribution and a measure of error are proposed.
openaire   +2 more sources

Incremental evolution of cellular automata for random number generation

open access: yes, 2003
Cellular automata (CA) have been used in pseudorandom number generation for over a decade. Recent studies show that controllable CA (CCA) can generate better random sequences than conventional one-dimensional (1-d) CA and compete with two-dimensional (2 ...
Zhang, S.   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Noise diodes as a source of entropy for hardware random number generators

open access: yesБезопасность информационных технологий, 2023
The purpose of this article is to describe the use of digital noise generators based on semiconductor noise diodes as part of systems for generating key numerical sequences used in cryptographic security methods.
Dmitry O. Petrov   +3 more
doaj   +1 more source

Pseudorandom number generation based on controllable cellular automata

open access: yes, 2004
A novel Cellular Automata (CA) Controllable CA (CCA) is proposed in this paper. Further, CCA are applied in Pseudorandom Number Generation. Randomness test results on CCA Pseudorandom Number Generators (PRNGs) show that they are better than 1-d CA PRNGs
Zhang, S.   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Distributed random number generation [PDF]

open access: yesJournal of Functional Programming, 1992
Abstract In a functional program, a simple random number generator may generate a lazy list of random numbers. This is fine when the random numbers are consumed sequentially at a single point in the program. However, things are more complicated in a program where random numbers are used at many locations, such as in a large simulation.
F. Warren Burton, Rex L. Page
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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