Big Data in Cancer Genomics: Computational Foundations and Emerging Pathways for Precision Oncology
ABSTRACT This review aims to explore the computational foundations of big data in cancer genomics and examine emerging pathways that support precision oncology and personalized cancer care. A narrative review approach was adopted to synthesize evidence from PubMed, Scopus, Web of Science, and IEEE Xplore.
Nur Vanu +8 more
wiley +1 more source
Ergodicity and regime recoverability in finite Markov-modulated random walks. [PDF]
Pambukyan A, Saudagar AKJ, Kumar S.
europepmc +1 more source
ABSTRACT Rare cancers collectively represent 20%–25% of all malignancies yet yield fewer than 50 annotated whole‐slide images (WSIs) per subtype in publicly available archives, rendering supervised deep learning inapplicable. We present HierAnom‐Path, to the best of our knowledge, the first framework for zero‐shot rare cancer anomaly detection in ...
Noora Saleem Jumaah +5 more
wiley +1 more source
Class-adaptive oracle-free metamorphic test case prioritization framework for vision-based deep neural networks. [PDF]
Li J, Mohamad R, Ahmad J.
europepmc +1 more source
When Does Hope Drive Social Change? Empirical Insights and Their Policy Implications
ABSTRACT When and how does people's hope for change drive social transformation? This question has gained urgency amidst the profound sociopolitical crises of the 21st century, including escalating intergroup conflicts, accelerating environmental degradation, and mounting threats to democracy.
Oded Adomi Leshem, Eran Halperin
wiley +1 more source
On the equivalence between classically verifiable position verification and certified randomness. [PDF]
Kaleoglu F +6 more
europepmc +1 more source
Abstract High temperatures lead to a significant drop in rice (Oryza sativa L.) productivity worldwide, especially during the reproductive stage. This research was piloted to evaluate 10 promising rice cultivars for their ability to withstand high‐temperature stress (HS) during the reproductive phase and to assess the impact on physiology and yield ...
Summiya Faisal +9 more
wiley +1 more source
Nevermore: Target-Conditioned Protein-Ligand Representation Learning for Multi-Objective Lead Optimization with Database-Grounded Retrieval. [PDF]
Refahi MS +6 more
europepmc +1 more source
Do Androids Dream of Electric Sheep? A Psychoanalytic Inquiry Into Large Language Models
ABSTRACT Large language models produce fluent, contextually appropriate language that invites the inference that something behind the output is thinking. The psychoanalytic theory of thinking, specifically the work of Wilfred Bion and Donald Winnicott read together, allows us to specify what thinking requires, what the LLM lacks, and what occurs when a
Mustafa Selek
wiley +1 more source
Hybrid Quantum-Classical Algorithm for Robust Optimization via Stochastic-Gradient Online Learning. [PDF]
Lim D, Doriguello JF, Rebentrost P.
europepmc +1 more source

